KEGG   Homo sapiens (human): 155Help
Entry
155               CDS       T01001                                 

Gene name
ADRB3, BETA3AR
Definition
(RefSeq) adrenoceptor beta 3
  KO
K04143  
adrenergic receptor beta-3
Organism
hsa  Homo sapiens (human)
Pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Regulation of lipolysis in adipocytes
Renin secretion
Salivary secretion
Drug target
Epinephrine: 
Isoprenaline: 
Norepinephrine: 
Arbutamine: 
Ephedrine: 
Buphenine: 
Alprenolol: 
Oxprenolol: 
Pindolol: 
Propranolol: 
Timolol: 
Nadolol: 
Mepindolol: 
Carteolol: 
Tertatolol: 
Bopindolol: 
Bupranolol: 
Penbutolol: 
Cloranolol: 
Labetalol: 
Carvedilol: 
Mirabegron: 
Pseudoephedrine: 
Isoprenaline: 
Dipivefrine: 
Levobunolol: 
Metipranolol: 
Befunolol: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    155 (ADRB3)
   04022 cGMP - PKG signaling pathway
    155 (ADRB3)
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    155 (ADRB3)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    155 (ADRB3)
 Organismal Systems
  Endocrine system
   04923 Regulation of lipolysis in adipocyte
    155 (ADRB3)
   04924 Renin secretion
    155 (ADRB3)
  Digestive system
   04970 Salivary secretion
    155 (ADRB3)
G protein-coupled receptors [BR:hsa04030]
 Class A. Rhodopsin family
  Biogenic amine [Fig]
   Adrenaline [OT]
    155 (ADRB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
8p12
AA seq 408 aa AA seqDB search
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
NT seq 1227 nt NT seq  +upstreamnt  +downstreamnt
atggctccgtggcctcacgagaacagctctcttgccccatggccggacctccccaccctg
gcgcccaataccgccaacaccagtgggctgccaggggttccgtgggaggcggccctagcc
ggggccctgctggcgctggcggtgctggccaccgtgggaggcaacctgctggtcatcgtg
gccatcgcctggactccgagactccagaccatgaccaacgtgttcgtgacttcgctggcc
gcagccgacctggtgatgggactcctggtggtgccgccggcggccaccttggcgctgact
ggccactggccgttgggcgccactggctgcgagctgtggacctcggtggacgtgctgtgt
gtgaccgccagcatcgaaaccctgtgcgccctggccgtggaccgctacctggctgtgacc
aacccgctgcgttacggcgcactggtcaccaagcgctgcgcccggacagctgtggtcctg
gtgtgggtcgtgtcggccgcggtgtcgtttgcgcccatcatgagccagtggtggcgcgta
ggggccgacgccgaggcgcagcgctgccactccaacccgcgctgctgtgccttcgcctcc
aacatgccctacgtgctgctgtcctcctccgtctccttctaccttcctcttctcgtgatg
ctcttcgtctacgcgcgggttttcgtggtggctacgcgccagctgcgcttgctgcgcggg
gagctgggccgctttccgcccgaggagtctccgccggcgccgtcgcgctctctggccccg
gccccggtggggacgtgcgctccgcccgaaggggtgcccgcctgcggccggcggcccgcg
cgcctcctgcctctccgggaacaccgggccctgtgcaccttgggtctcatcatgggcacc
ttcactctctgctggttgcccttctttctggccaacgtgctgcgcgccctggggggcccc
tctctagtcccgggcccggctttccttgccctgaactggctaggttatgccaattctgcc
ttcaacccgctcatctactgccgcagcccggactttcgcagcgccttccgccgtcttctg
tgccgctgcggccgtcgcctgcctccggagccctgcgccgccgcccgcccggccctcttc
ccctcgggcgttcctgcggcccggagcagcccagcgcagcccaggctttgccaacggctc
gacggggcttcttggggagtttcttag

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