KEGG   Homo sapiens (human): 155Help
Entry
155               CDS       T01001                                 

Gene name
ADRB3, BETA3AR
Definition
(RefSeq) adrenoceptor beta 3
  KO
K04143  
adrenergic receptor beta-3
Organism
hsa  Homo sapiens (human)
Pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Regulation of lipolysis in adipocytes
Renin secretion
Salivary secretion
Drug target
Alprenolol (DG00303): 
Amibegron (DG01237): 
Befunolol (DG01138): 
Beradilol monoethyl maleate: 
Bopindolol (DG00310): 
Bufetolol (DG02507): 
Bupranolol (DG00311): 
Carteolol (DG00308): 
Cloranolol: 
Deterenol hydrochloride: 
Dilevalol hydrochloride: 
Dipivefrine (DG01129): 
Droxidopa: 
Ephedrine (DG00227): 
Epinephrine (DG00013): 
Epinephryl borate: 
Etilefrine (DG00210): 
Isoprenaline (DG00211): 
Levobunolol (DG01136): 
Medroxalol (DG01317): 
Mephentermine (DG00220): 
Mepindolol: 
Methylephedrine (DG01229): 
Metipranolol (DG01137): 
Metizoline: 
Mirabegron: 
Nipradilol (DG02533): 
Norepinephrine (DG00212): 
Octodrine: 
Oxprenolol (DG00304): 
Penbutolol (DG00312): 
Phenylpropanolamine (DG01041): 
Pindolol: 
Propranolol (DG00305): 
Pseudoephedrine (DG01042): 
Racephedrine Hydrochloride: 
Tazolol hydrochloride: 
Tertatolol (DG00309): 
Tilisolol (DG01322): 
Tiprenolol hydrochloride: 
Tolamolol: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    155 (ADRB3)
   04022 cGMP - PKG signaling pathway
    155 (ADRB3)
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    155 (ADRB3)
 Organismal Systems
  Endocrine system
   04923 Regulation of lipolysis in adipocyte
    155 (ADRB3)
   04924 Renin secretion
    155 (ADRB3)
  Digestive system
   04970 Salivary secretion
    155 (ADRB3)
G protein-coupled receptors [BR:hsa04030]
 Class A. Rhodopsin family
  Biogenic amine [Fig]
   Adrenaline [OT]
    155 (ADRB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P13945(Tclin)
UniProt: 
Position
8p11.23
AA seq 408 aa AA seqDB search
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
NT seq 1227 nt NT seq  +upstreamnt  +downstreamnt
atggctccgtggcctcacgagaacagctctcttgccccatggccggacctccccaccctg
gcgcccaataccgccaacaccagtgggctgccaggggttccgtgggaggcggccctagcc
ggggccctgctggcgctggcggtgctggccaccgtgggaggcaacctgctggtcatcgtg
gccatcgcctggactccgagactccagaccatgaccaacgtgttcgtgacttcgctggcc
gcagccgacctggtgatgggactcctggtggtgccgccggcggccaccttggcgctgact
ggccactggccgttgggcgccactggctgcgagctgtggacctcggtggacgtgctgtgt
gtgaccgccagcatcgaaaccctgtgcgccctggccgtggaccgctacctggctgtgacc
aacccgctgcgttacggcgcactggtcaccaagcgctgcgcccggacagctgtggtcctg
gtgtgggtcgtgtcggccgcggtgtcgtttgcgcccatcatgagccagtggtggcgcgta
ggggccgacgccgaggcgcagcgctgccactccaacccgcgctgctgtgccttcgcctcc
aacatgccctacgtgctgctgtcctcctccgtctccttctaccttcctcttctcgtgatg
ctcttcgtctacgcgcgggttttcgtggtggctacgcgccagctgcgcttgctgcgcggg
gagctgggccgctttccgcccgaggagtctccgccggcgccgtcgcgctctctggccccg
gccccggtggggacgtgcgctccgcccgaaggggtgcccgcctgcggccggcggcccgcg
cgcctcctgcctctccgggaacaccgggccctgtgcaccttgggtctcatcatgggcacc
ttcactctctgctggttgcccttctttctggccaacgtgctgcgcgccctggggggcccc
tctctagtcccgggcccggctttccttgccctgaactggctaggttatgccaattctgcc
ttcaacccgctcatctactgccgcagcccggactttcgcagcgccttccgccgtcttctg
tgccgctgcggccgtcgcctgcctccggagccctgcgccgccgcccgcccggccctcttc
ccctcgggcgttcctgcggcccggagcagcccagcgcagcccaggctttgccaacggctc
gacggggcttcttggggagtttcttag

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