KEGG T01001: 157

Homo sapiens (human): 157

Entry

157 CDS T01001

Gene name

ADRBK2, BARK2, GRK3

Definition

adrenergic, beta, receptor kinase 2 (EC:2.7.11.15)

Orthology

K00910

beta-adrenergic-receptor kinase [EC:2.7.11.15]

Organism

hsa Homo sapiens (human)

Pathway

hsa04062	Chemokine signaling pathway
hsa04144	Endocytosis
hsa04724	Glutamatergic synapse
hsa04740	Olfactory transduction
hsa05032	Morphine addiction

Class

Cellular Processes; Transport and catabolism; Endocytosis [PATH:hsa04144]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:hsa04062]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:hsa04724]
Organismal Systems; Sensory system; Olfactory transduction [PATH:hsa04740]
Human Diseases; Substance dependence; Morphine addiction [PATH:hsa05032]

SSDB

Motif

Pfam:

Pkinase Pkinase_Tyr RGS PH Kinase-like Kdo PH_11

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

22q12.1

AA seq 688 aa
MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN
QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC
SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE
IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE
LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK
RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL
LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR
APKFLNKPRSGTVELPKPSLCHRNSNGL

NT seq 2067 nt +upstreamnt +downstreamnt
atggcggacctggaggctgtgctggccgatgtcagttacctgatggccatggagaagagc
aaggcgaccccggccgcccgcgccagcaagaggatcgtcctgccggagcccagtatccgg
agtgtgatgcagaagtaccttgcagagagaaatgaaataacctttgacaagattttcaat
cagaaaattggtttcttgctatttaaagatttttgtttgaatgaaattaatgaagctgta
cctcaggtgaagttttatgaagagataaaggaatatgaaaaacttgataatgaggaagac
cgcctttgcagaagtcgacaaatttatgatgcctacatcatgaaggaacttctttcctgt
tcacatcctttctcaaagcaagctgtagaacacgtacaaagtcatttatccaagaaacaa
gtgacatcaactctttttcagccatacatagaagaaatttgtgaaagccttcgaggtgac
atttttcaaaaatttatggaaagtgacaagttcactagattttgtcagtggaaaaacgtt
gaattaaatatccatttgaccatgaatgagttcagtgtgcataggattattggacgagga
ggattcggggaagtttatggttgcaggaaagcagacactggaaaaatgtatgcaatgaaa
tgcttagataagaagaggatcaaaatgaaacaaggagaaacattagccttaaatgaaaga
atcatgttgtctcttgtcagcacaggagactgtcctttcattgtatgtatgacctatgcc
ttccataccccagataaactctgcttcatcctggatctgatgaacgggggcgatttgcac
taccacctttcacaacacggtgtgttctctgagaaggagatgcggttttatgccactgaa
atcattctgggtctggaacacatgcacaatcggtttgttgtctacagagatttgaagcca
gcaaatattctcttggatgaacatggacacgcaagaatatcagatcttggtcttgcctgc
gatttttccaaaaagaagcctcatgcgagtgttggcacccatgggtacatggctcccgag
gtgctgcagaaggggacggcctatgacagcagtgccgactggttctccctgggctgcatg
cttttcaaacttctgagaggtcacagccctttcagacaacataaaaccaaagacaagcat
gaaattgaccgaatgacactcaccgtgaatgtggaacttccagacaccttctctcctgaa
ctgaagtcccttttggagggcttgcttcagcgagacgttagcaagcggctgggctgtcac
ggaggcggctcacaggaagtaaaagagcacagctttttcaaaggtgttgactggcagcat
gtctacttacaaaagtacccaccacccttgattcctccccggggagaagtcaatgctgct
gatgcctttgatattggctcatttgatgaagaggataccaaagggattaagctacttgat
tgcgaccaagaactctacaagaacttccctttggtcatctctgaacgctggcagcaagaa
gtaacggaaacagtttatgaagcagtaaatgcagacacagataaaatcgaggccaggaag
agagctaaaaataagcaacttggccacgaagaagattacgctctggggaaggactgtatt
atgcacgggtacatgctgaaactgggaaacccatttctgactcagtggcagcgtcgctat
ttttacctctttccaaatagacttgaatggagaggagagggagagtcccggcaaaattta
ctgacaatggaacagattctctctgtggaagaaactcaaattaaagacaaaaaatgcatt
ttgttcagaataaaaggagggaaacaatttgtcttgcaatgtgagagtgatccagagttt
gtgcagtggaagaaagagttgaacgaaaccttcaaggaggcccagcggctattgcgtcgt
gccccgaagttcctcaacaaacctcggtcaggtactgtggagctcccaaagccatccctc
tgtcacagaaacagcaacggcctctag

All links

Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (4)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (25)   
   RefSeq(nuc) (1)   
   GenBank (12)   
   EMBL (12)   
Protein domain (7)   
   Pfam (7)   
All databases (53)   

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