| Entry |
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| Gene name |
ADSL, AMPS, ASASE, ASL
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| Definition |
adenylosuccinate lyase (EC:4.3.2.2)
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| Orthology |
| adenylosuccinate lyase [EC: 4.3.2.2] |
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| Organism |
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| Pathway |
| Purine metabolism | | Alanine, aspartate and glutamate metabolism | | Metabolic pathways |
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| Module |
| Inosine monophosphate biosynthesis, PRPP + glutamine => IMP | | Adenine ribonucleotide biosynthesis, IMP => ADP,ATP |
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| Disease |
| Adenylosuccinate lyase deficiency |
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| Class |
Metabolism; Nucleotide metabolism; Purine metabolism [PATH: hsa00230]
Metabolism; Amino acid metabolism; Alanine, aspartate and glutamate metabolism [PATH: hsa00250]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: UniProt: |
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| Structure |
PDB: |
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| Position |
22q13.2
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| AA seq |
484 aa  
MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDE
QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTD
LIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC
MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG
QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMR
SERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE
GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGD
NDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKA
ELCL |
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| NT seq |
1455 nt  +upstreamnt +downstreamnt
atggcggctggaggcgatcatggttcgcccgacagctaccgctcacctcttgcctcccgc
tatgccagcccggagatgtgcttcgtgtttagcgacaggtataaattccggacatggcgg
cagctgtggctgtggctggcggaggccgagcagacattgggtttgcctatcacagatgaa
caaatccaggagatgaaatcaaacctggagaacatcgacttcaagatggcagctgaggaa
gagaaacgtttacgacatgatgtgatggctcacgtgcacacatttggccactgctgtcca
aaagctgcaggcattattcaccttggtgctacttcttgctatgttggagacaatactgac
ttgattattcttagaaatgcacttgacctgcttttgccaaagcttgccagagtgatctct
cggcttgccgactttgctaaggaacgagccagtctacccacattaggtttcacacatttc
cagcctgcacagctgaccacagttgggaaacgttgctgtctttggattcaggatctttgc
atggatctccagaacttgaagcgtgtccgagatgacctgcgcttccggggagtaaagggt
accactggcactcaggccagtttcctgcagctctttgagggagatgaccataaggtagag
cagcttgacaagatggtgacagaaaaggcaggatttaagagagctttcatcatcacaggg
cagacatatacacgaaaagtggatattgaagtactgtctgtgctggctagcttgggggca
tcagtgcacaagatttgcaccgacatacgcctcctggcaaacctcaaggagatggaggaa
ccctttgaaaaacagcagattggctcaagtgcgatgccatataagcggaatcccatgcgt
tcagaacgttgctgcagtcttgcccgccacctgatgacccttgtcatggacccgctacag
acagcatctgtccagtggtttgaacgcacactggatgatagtgccaaccgacggatctgt
ttggccgaggcatttcttaccgcagatactatattgaatacgctgcagaacatttctgaa
ggattggtcgtgtaccccaaagtaattgaacggcgcattcggcaagagctgcctttcatg
gccacagagaacatcatcatggccatggtcaaagctggaggtagccgccaggattgccat
gagaaaatcagagtgctttctcagcaggcagcttctgtggttaagcaggaagggggtgac
aatgacctcatagagcgtatccaggttgatgcctacttcagtcccattcactcccagttg
gatcatttactggatccttcttctttcactggtcgtgcctcccagcaggtgcagagattc
ttagaagaggaggtgtatcccctgttaaaaccatatgaaagcgtgatgaaggtgaaagca
gaattatgtctgtag |
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