KEGG   Homo sapiens (human): 1785Help
Entry
1785              CDS       T01001                                 

Gene name
DNM2, CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5
Definition
dynamin 2 (EC:3.6.5.5)
Orthology
K01528  
dynamin GTPase [EC:3.6.5.5]
Organism
hsa  Homo sapiens (human)
Pathway
Endocytosis
Fc gamma R-mediated phagocytosis
Synaptic vesicle cycle
Endocrine and other factor-regulated calcium reabsorption
Bacterial invasion of epithelial cells
Disease
H00264  
Charcot-Marie-Tooth disease (CMT)
H00700  
Centronuclear myopathy
Class
Cellular Processes; Transport and catabolism; Endocytosis [PATH:hsa04144]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:hsa04666]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:hsa04961]
Organismal Systems; Nervous system; Synaptic vesicle cycle [PATH:hsa04721]
Human Diseases; Infectious diseases; Bacterial invasion of epithelial cells [PATH:hsa05100]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
19p13.2
AA seq 870 aa AA seqDB search
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL
KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID
IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE
YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL
RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV
DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD
DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR
PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP
GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD
NT seq 2613 nt NT seq  +upstreamnt  +downstreamnt
atgggcaaccgcgggatggaagagctgatcccgctggtcaacaaactgcaggacgccttc
agctccatcggccagagctgccacctggacctgccgcagatcgctgtagtgggcggccag
agcgccggcaagagctcggtgctggagaacttcgtgggccgggacttccttccccgcggt
tcaggaatcgtcacccggcggcctctcattctgcagctcatcttctcaaaaacagaacat
gccgagtttttgcactgcaagtccaaaaagtttacagactttgatgaagtccggcaggag
attgaagcagagaccgacagggtcacggggaccaacaaaggcatctccccagtgcccatc
aaccttcgagtctactcgccacacgtgttgaacttgaccctcatcgacctcccgggtatc
accaaggtgcctgtgggcgaccagcctccagacatcgagtaccagatcaaggacatgatc
ctgcagttcatcagccgggagagcagcctcattctggctgtcacgcccgccaacatggac
ctggccaactccgacgccctcaagctggccaaggaagtcgatccccaaggcctacggacc
atcggtgtcatcaccaagcttgacctgatggacgagggcaccgacgccagggacgtcttg
gagaacaagttgctcccgttgagaagaggctacattggcgtggtgaaccgcagccagaag
gatattgagggcaagaaggacatccgtgcagcactggcagctgagaggaagttcttcctc
tcccacccggcctaccggcacatggccgaccgcatgggcacgccacatctgcagaagacg
ctgaatcagcaactgaccaaccacatccgggagtcgctgccggccctacgtagcaaacta
cagagccagctgctgtccctggagaaggaggtggaggagtacaagaactttcggcccgac
gaccccacccgcaaaaccaaagccctgctgcagatggtccagcagtttggggtggatttt
gagaagaggatcgagggctcaggagatcaggtggacactctggagctctccgggggcgcc
cgaatcaatcgcatcttccacgagcggttcccatttgagctggtgaagatggagtttgac
gagaaggacttacgacgggagatcagctatgccattaagaacatccatggagtcaggacc
gggcttttcaccccggacttggcattcgaggccattgtgaaaaagcaggtcgtcaagctg
aaagagccctgtctgaaatgtgtcgacctggttatccaggagctaatcaatacagttagg
cagtgtaccagtaagctcagttcctacccccggttgcgagaggagacagagcgaatcgtc
accacttacatccgggaacgggaggggagaacgaaggaccagattcttctgctgatcgac
attgagcagtcctacatcaacacgaaccatgaggacttcatcgggtttgccaatgcccag
cagaggagcacgcagctgaacaagaagagagccatccccaatcagggggagatcctggtg
atccgcaggggctggctgaccatcaacaacatcagcctgatgaaaggcggctccaaggag
tactggtttgtgctgactgccgagtcactgtcctggtacaaggatgaggaggagaaagag
aagaagtacatgctgcctctggacaacctcaagatccgtgatgtggagaagggcttcatg
tccaacaagcacgtcttcgccatcttcaacacggagcagagaaacgtctacaaggacctg
cggcagatcgagctggcctgtgactcccaggaagacgtggacagctggaaggcctcgttc
ctccgagctggcgtctaccccgagaaggaccaggcagaaaacgaggatggggcccaggag
aacaccttctccatggacccccaactggagcggcaggtggagaccattcgcaacctggtg
gactcatacgtggccatcatcaacaagtccatccgcgacctcatgccaaagaccatcatg
cacctcatgatcaacaatacgaaggccttcatccaccacgagctgctggcctacctatac
tcctcggcagaccagagcagcctcatggaggagtcggctgaccaggcacagcggcgggac
gacatgctgcgcatgtaccatgccctcaaggaggcgctcaacatcatcggtgacatcagc
accagcactgtgtccacgcctgtacccccgcctgtcgatgacacctggctccagagcgcc
agcagccacagccccactccacagcgccgaccggtgtccagcatacacccccctggccgg
cccccagcagtgaggggccccactccagggccccccctgattcctgttcccgtgggggca
gcagcctccttctcggcgcccccaatcccatcccggcctggaccccagagcgtgtttgcc
aacagtgacctcttcccagccccgcctcagatcccatctcggccagttcggatcccccca
gggattcccccaggagtgcccagcagaagaccccctgctgcgcccagccggcccaccatt
atccgcccagccgagccatccctgctcgactag

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