KEGG   Homo sapiens (human): 1832Help
Entry
1832              CDS       T01001                                 

Gene name
DSP, DP, DPI, DPII
Definition
desmoplakin
Orthology
K10381  
desmoplakin
Organism
hsa  Homo sapiens (human)
Pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Disease
H00293  
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
H00584  
Epidermolysis bullosa simplex
H00669  
Naxos disease and Carvajal syndrome
H00717  
Striate palmoplantar keratoderma
H00893  
Skin fragility-woolly hair syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Human Diseases
  Cardiovascular diseases
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    1832 (DSP)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   1832 (DSP)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
6p24
AA seq 2272 aa AA seqDB search
MSCNGGSHPRINTLGRMIRAESGPDLRYEVTSGGGGTSRMYYSRRGVITDQNSDGYCQTG
TMSRHQNQNTIQELLQNCSDCLMRAELIVQPELKYGDGIQLTRSRELDECFAQANDQMEI
LDSLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGW
DEFTKHVTSECLGWMRQQRAEMDMVAWGVDLASVEQHINSHRGIHNSIGDYRWQLDKIKA
DLREKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSD
KNTNIAQKQEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSW
ILQITKCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKE
LEKEREKILEYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGD
ECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQL
YINMKSLVSWHYCMIDIEKIRAMTIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMF
GDDDKRKIQSQFTDAQKHYQTLVIQLPGYPQHQTVTTTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELKSVQNDSQAIA
EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAILQT
EDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQIHS
QTSQQYPLYDLDLGKFGEKVTQLTDRWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCK
WLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAELCANSIKD
YELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDYYRFLSEM
LKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLE
ELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYD
QLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKASNRIQ
ESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQ
IQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLED
STRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQ
LYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKL
ISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGFDDP
FSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRDLY
RSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTV
TELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMK
IGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGY
NDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNE
ELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKN
TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQECEWEEITITGSDGSTRVVL
VDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMISLKNGVGTSSSMGSGVSD
DVFSSSRHESVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIER
GIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFE
GVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGR
AAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNM
SSAPGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYSYSYSFSSSSIGH
NT seq 6819 nt NT seq  +upstreamnt  +downstreamnt
atgagctgcaacggaggctcccacccgcggatcaacactctgggccgcatgatccgcgcc
gagtctggcccggacctgcgctacgaggtgaccagcggcggcgggggcaccagcaggatg
tactattctcggcgcggcgtgatcaccgaccagaactcggacggctactgtcaaaccggc
acgatgtccaggcaccagaaccagaacaccatccaggagctgctgcagaactgctccgac
tgcttgatgcgagcagagctcatcgtgcagcctgaattgaagtatggagatggaatacaa
ctgactcggagtcgagaattggatgagtgttttgcccaggccaatgaccaaatggaaatc
ctcgacagcttgatcagagagatgcggcagatgggccagccctgtgatgcttaccagaaa
aggcttcttcagctccaagagcaaatgcgagccctttataaagccatcagtgtccctcga
gtccgcagggccagctccaagggtggtggaggctacacttgtcagagtggctctggctgg
gatgagttcaccaaacatgtcaccagtgaatgtttggggtggatgaggcagcaaagggcg
gagatggacatggtggcctggggtgtggacctggcctcagtggagcagcacattaacagc
caccggggcatccacaactccatcggcgactatcgctggcagctggacaaaatcaaagcc
gacctgcgcgagaaatctgcgatctaccagttggaggaggagtatgaaaacctgctgaaa
gcgtcctttgagaggatggatcacctgcgacagctgcagaacatcattcaggccacgtcc
agggagatcatgtggatcaatgactgcgaggaggaggagctgctgtacgactggagcgac
aagaacaccaacatcgctcagaaacaggaggccttctccatacgcatgagtcaactggaa
gttaaagaaaaagagctcaataagctgaaacaagaaagtgaccaacttgtcctcaatcag
catccagcttcagacaaaattgaggcctatatggacactctgcagacgcagtggagttgg
attcttcagatcaccaagtgcattgatgttcatctgaaagaaaatgctgcctactttcag
ttttttgaagaggcgcagtctactgaagcatacctgaaggggctccaggactccatcagg
aagaagtacccctgcgacaagaacatgcccctgcagcacctgctggaacagatcaaggag
ctggagaaagaacgagagaaaatccttgaatacaagcgtcaggtgcagaacttggtaaac
aagtctaagaagattgtacagctgaagcctcgtaacccagactacagaagcaataaaccc
attattctcagagctctctgtgactacaaacaagatcagaaaatcgtgcataagggggat
gagtgtatcctgaaggacaacaacgagcgcagcaagtggtacgtgacgggcccgggaggc
gttgacatgcttgttccctctgtggggctgatcatccctcctccgaacccactggccgtg
gacctctcttgcaagattgagcagtactacgaagccatcttggctctgtggaaccagctc
tacatcaacatgaagagcctggtgtcctggcactactgcatgattgacatagagaagatc
agggccatgacaatcgccaagctgaaaacaatgcggcaggaagattacatgaagacgata
gccgaccttgagttacattaccaagagttcatcagaaatagccaaggctcagagatgttt
ggagatgatgacaagcggaaaatacagtctcagttcaccgatgcccagaagcattaccag
accctggtcattcagctccctggctatccccagcaccagacagtgaccacaactgaaatc
actcatcatggaacctgccaagatgtcaaccataataaagtaattgaaaccaacagagaa
aatgacaagcaagaaacatggatgctgatggagctgcagaagattcgcaggcagatagag
cactgcgagggcaggatgactctcaaaaacctccctctagcagaccaggggtcttctcac
cacatcacagtgaaaattaacgagcttaagagtgtgcagaatgattcacaagcaattgct
gaggttctcaaccagcttaaagatatgcttgccaacttcagaggttctgaaaagtactgc
tatttacagaatgaagtatttggactatttcagaaactggaaaatatcaatggtgttaca
gatggctacttaaatagcttatgcacagtaagggcactgctccaggctattctccaaaca
gaagacatgttaaaggtttatgaagccaggctcactgaggaggaaactgtctgcctggac
ctggataaagtggaagcttaccgctgtggactgaagaaaataaaaaatgacttgaacttg
aagaagtcgttgttggccactatgaagacagaactacagaaagcccagcagatccactct
cagacttcacagcagtatccactttatgatctggacttgggcaagttcggtgaaaaagtc
acacagctgacagaccgctggcaaaggatagataaacagatcgactttaggttatgggac
ctggagaaacaaatcaagcaattgaggaattatcgtgataactatcaggctttctgcaag
tggctctatgatgctaaacgccgccaggattccttagaatccatgaaatttggagattcc
aacacagtcatgcggtttttgaatgagcagaagaacttgcacagtgaaatatctggcaaa
cgagacaaatcagaggaagtacaaaaaattgctgaactttgcgccaattcaattaaggat
tatgagctccagctggcctcatacacctcaggactggaaactctgctgaacatacctatc
aagaggaccatgattcagtccccttctggggtgattctgcaagaggctgcagatgttcat
gctcggtacattgaactacttacaagatctggagactattacaggttcttaagtgagatg
ctgaagagtttggaagatctgaagctgaaaaataccaagatcgaagttttggaagaggag
ctcagactggcccgagatgccaactcggaaaactgtaataagaacaaattcctggatcag
aacctgcagaaataccaggcagagtgttcccagttcaaagcgaagcttgcgagcctggag
gagctgaagagacaggctgagctggatgggaagtcggctaagcaaaatctagacaagtgc
tacggccaaataaaagaactcaatgagaagatcacccgactgacttatgagattgaagat
gaaaagagaagaagaaaatctgtggaagacagatttgaccaacagaagaatgactatgac
caactgcagaaagcaaggcaatgtgaaaaggagaaccttggttggcagaaattagagtct
gagaaagccatcaaggagaaggagtacgagattgaaaggttgagggttctactgcaggaa
gaaggcacccggaagagagaatatgaaaatgagctggcaaaggcatctaataggattcag
gaatcaaagaatcagtgtactcaggtggtacaggaaagagagagccttctggtgaaaatc
aaagtcctggagcaagacaaggcaaggctgcagaggctggaggatgagctgaatcgtgca
aaatcaactctagaggcagaaaccagggtgaaacagcgcctggagtgtgagaaacagcaa
attcagaatgacctgaatcagtggaagactcaatattcccgcaaggaggaggctattagg
aagatagaatcggaaagagaaaagagtgagagagagaagaacagtcttaggagtgagatc
gaaagactccaagcagagatcaagagaattgaagagaggtgcaggcgtaagctggaggat
tctaccagggagacacagtcacagttagaaacagaacgctcccgatatcagagggagatt
gataaactcagacagcgcccatatgggtcccatcgagagacccagactgagtgtgagtgg
accgttgacacctccaagctggtgtttgatgggctgaggaagaaggtgacagcaatgcag
ctctatgagtgtcagctgatcgacaaaacaaccttggacaaactattgaaggggaagaag
tcagtggaagaagttgcttctgaaatccagccattccttcggggtgcaggatctatcgct
ggagcatctgcttctcctaaggaaaaatactctttggtagaggccaagagaaagaaatta
atcagcccagaatccacagtcatgcttctggaggcccaggcagctacaggtggtataatt
gatccccatcggaatgagaagctgactgtcgacagtgccatagctcgggacctcattgac
ttcgatgaccgtcagcagatatatgcagcagaaaaagctatcactggttttgatgatcca
ttttcaggcaagacagtatctgtttcagaagccatcaagaaaaatttgattgatagagaa
accggaatgcgcctgctggaagcccagattgcttcagggggtgtagtagaccctgtgaac
agtgtctttttgccaaaagatgtcgccttggcccgggggctgattgatagagatttgtat
cgatccctgaatgatccccgagatagtcagaaaaactttgtggatccagtcaccaaaaag
aaggtcagttacgtgcagctgaaggaacggtgcagaatcgaaccacatactggtctgctc
ttgctttcagtacagaagagaagcatgtccttccaaggaatcagacaacctgtgaccgtc
actgagctagtagattctggtatattgagaccgtccactgtcaatgaactggaatctggt
cagatttcttatgacgaggttggtgagagaattaaggacttcctccagggttcaagctgc
atagcaggcatatacaatgagaccacaaaacagaagcttggcatttatgaggccatgaaa
attggcttagtccgacctggtactgctctggagttgctggaagcccaagcagctactggc
tttatagtggatcctgttagcaacttgaggttaccagtggaggaagcctacaagagaggt
ctggtgggcattgagttcaaagagaagctcctgtctgcagaacgagctgtcactgggtat
aatgatcctgaaacaggaaacatcatctctttgttccaagccatgaataaggaactcatc
gaaaagggccacggtattcgcttattagaagcacagatcgcaaccggggggatcattgac
ccaaaggagagccatcgtttaccagttgacatagcatataagaggggctatttcaatgag
gaactcagtgagattctctcagatccaagtgatgataccaaaggattttttgaccccaac
actgaagaaaatcttacctatctgcaactaaaagaaagatgcattaaggatgaggaaaca
gggctctgtcttctgcctctgaaagaaaagaagaaacaggtgcagacatcacaaaagaat
accctcaggaagcgtagagtggtcatagttgacccagaaaccaataaagaaatgtctgtt
caggaggcctacaagaagggcctaattgattatgaaaccttcaaagaactgtgtgagcag
gaatgtgaatgggaagaaataaccatcacgggatcagatggctccaccagggtggtcctg
gtagatagaaagacaggcagtcagtatgatattcaagatgctattgacaagggccttgtt
gacaggaagttctttgatcagtaccgatccggcagcctcagcctcactcaatttgctgac
atgatctccttgaaaaatggtgtcggcaccagcagcagcatgggcagtggtgtcagcgat
gatgtttttagcagctcccgacatgaatcagtaagtaagatttccaccatatccagcgtc
aggaatttaaccataaggagcagctctttttcagacaccctggaagaatcgagccccatt
gcagccatctttgacacagaaaacctggagaaaatctccattacagaaggtatagagcgg
ggcatcgttgacagcatcacgggtcagaggcttctggaggctcaggcctgcacaggtggc
atcatccacccaaccacgggccagaagctgtcacttcaggacgcagtctcccagggtgtg
attgaccaagacatggccaccaggctgaagcctgctcagaaagccttcataggcttcgag
ggtgtgaagggaaagaagaagatgtcagcagcagaggcagtgaaagaaaaatggctcccg
tatgaggctggccagcgcttcctggagttccagtacctcacgggaggtcttgttgacccg
gaagtgcatgggaggataagcaccgaagaagccatccggaaggggttcatagatggccgc
gccgcacagaggctgcaagacaccagcagctatgccaaaatcctgacctgccccaaaacc
aaattaaaaatatcctataaggatgccataaatcgctccatggtagaagatatcactggg
ctgcgccttctggaagccgcctccgtgtcgtccaagggcttacccagcccttacaacatg
tcttcggctccggggtcccgctccggctcccgctcgggatctcgctccggatctcgctcc
gggtcccgcagtgggtcccggagaggaagctttgacgccacagggaattcttcctactct
tattcctactcatttagcagtagttctattgggcactag

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