KEGG T01001: 20

Homo sapiens (human): 20

Entry

20 CDS T01001

Gene name

ABCA2, ABC2

Definition

ATP-binding cassette, sub-family A (ABC1), member 2

Orthology

K05642

ATP-binding cassette, subfamily A (ABC1), member 2

Organism

hsa Homo sapiens (human)

Pathway

hsa02010	ABC transporters
hsa04142	Lysosome

Class

Environmental Information Processing; Membrane transport; ABC transporters [PATH:hsa02010]
Cellular Processes; Transport and catabolism; Lysosome [PATH:hsa04142]

SSDB

Motif

Pfam:

ABC_tran ABC2_membrane_3 AAA_21 AAA_15 AAA_23 AAA_29

Other DBs

NCBI-GI:

45446740

NCBI-GeneID:

OMIM:

600047

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

9q34

AA seq 2436 aa
MGFLHQLQLLLWKNVTLKRRSPWVLAFEIFIPLVLFFILLGLRQKKPTISVKEVSFYTAA
PLTSAGILPVMQSLCPDGQRDEFGFLQYANSTVTQLLERLDRVVEEGNLFDPARPSLGSE
LEALRQHLEALSAGPGTSGSHLDRSTVSSFSLDSVARNPQELWRFLTQNLSLPNSTAQAL
LAARVDPPEVYHLLFGPSSALDSQSGLHKGQEPWSRLGGNPLFRMEELLLAPALLEQLTC
TPGSGELGRILTVPESQKGALQGYRDAVCSGQAAARARRFSGLSAELRNQLDVAKVSQQL
GLDAPNGSDSSPQAPPPRRLQALLGDLLDAQKVLQDVDVLSALALLLPQGACTGRTPGPP
ASGAGGAANGTGAGAVMGPNATAEEGAPSAAALATPDTLQGQCSAFVQLWAGLQPILCGN
NRTIEPEALRRGNMSSLGFTSKEQRNLGLLVHLMTSNPKILYAPAGSEVDRVILKANETF
AFVGNVTHYAQVWLNISAEIRSFLEQGRLQQHLRWLQQYVAELRLHPEALNLSLDELPPA
LRQDNFSLPSGMALLQQLDTIDNAACGWIQFMSKVSVDIFKGFPDEESIVNYTLNQAYQD
NVTVFASVIFQTRKDGSLPPHVHYKIRQNSSFTEKTNEIRRAYWRPGPNTGGRFYFLYGF
VWIQDMMERAIIDTFVGHDVVEPGSYVQMFPYPCYTRDDFLFVIEHMMPLCMVISWVYSV
AMTIQHIVAEKEHRLKEVMKTMGLNNAVHWVAWFITGFVQLSISVTALTAILKYGQVLMH
SHVVIIWLFLAVYAVATIMFCFLVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAH
DKITAFEKCIASLMSTTAFGLGSKYFALYEVAGVGIQWHTFSQSPVEGDDFNLLLAVTML
MVDAVVYGILTWYIEAVHPGMYGLPRPWYFPLQKSYWLGSGRTEAWEWSWPWARTPRLSV
MEEDQACAMESRRFEETRGMEEEPTHLPLVVCVDKLTKVYKDDKKLALNKLSLNLYENQV
VSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRL
TVEEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAIAFVG
GSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKL
KCCGSPLFLKGTYGDGYRLTLVKRPAEPGGPQEPGLASSPPGRAPLSSCSELQVSQFIRK
HVASCLLVSDTSTELSYILPSEAAKKGAFERLFQHLERSLDALHLSSFGLMDTTLEEVFL
KVSEEDQSLENSEADVKESRKDVLPGAEGPASGEGHAGNLARCSELTQSQASLQSASSVG
SARGDEGAGYTDVYGDYRPLFDNPQDPDNVSLQEVEAEALSRVGQGSRKLDGGWLKVRQF
HGLLVKRFHCARRNSKALFSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSPSQYHNYTQ
PRGNFIPYANEERREYRLRLSPDASPQQLVSTFRLPSGVGATCVLKSPANGSLGPTLNLS
SGESRLLAARFFDSMCLESFTQGLPLSNFVPPPPSPAPSDSPASPDEDLQAWNVSLPPTA
GPEMWTSAPSLPRLVREPVRCTCSAQGTGFSCPSSVGGHPPQMRVVTGDILTDITGHNVS
EYLLFTSDRFRLHRYGAITFGNVLKSIPASFGTRAPPMVRKIAVRRAAQVFYNNKGYHSM
PTYLNSLNNAILRANLPKSKGNPAAYGITVTNHPMNKTSASLSLDYLLQGTDVVIAIFII
VAMSFVPASFVVFLVAEKSTKAKHLQFVSGCNPIIYWLANYVWDMLNYLVPATCCVIILF
VFDLPAYTSPTNFPAVLSLFLLYGWSITPIMYPASFWFEVPSSAYVFLIVINLFIGITAT
VATFLLQLFEHDKDLKVVNSYLKSCFLIFPNYNLGHGLMEMAYNEYINEYYAKIGQFDKM
KSPFEWDIVTRGLVAMAVEGVVGFLLTIMCQYNFLRRPQRMPVSTKPVEDDVDVASERQR
VLRGDADNDMVKIENLTKVYKSRKIGRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKM
LTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISW
KDEARVVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPK
ARRFLWNLILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLRCLGSIQHLKNRFGDG
YMITVRTKSSQSVKDVVRFFNRNFPEAMLKERHHTKVQYQLKSEHISLAQVFSKMEQVSG
VLGIEDYSVSQTTLDNVFVNFAKKQSDNLEQQETEPPSALQSPLGCLLSLLRPRSAPTEL
RALVADEPEDLDTEDEGLISFEEERAQLSFNTDTLC

NT seq 7311 nt +upstreamnt +downstreamnt
atgggcttcctgcaccagctgcagctgctgctctggaagaacgtgacgctcaaacgccgg
agcccgtgggtcctggccttcgagatcttcatccccctggtgctgttctttatcctgctg
gggctgcgacagaagaagcccaccatctccgtgaaggaagtctccttctacacagcggcg
cccctgacgtctgccggcatcctgcctgtcatgcaatcgctgtgcccggacggccagcga
gacgagttcggcttcctgcagtacgccaactccacggtcacgcagctgcttgagcgcctg
gaccgcgtggtggaggaaggcaacctgtttgacccagcgcggcccagcctgggctcagag
ctcgaggccctacgccagcatctggaggccctcagtgcgggcccgggcacctcggggagc
cacctggacagatccacagtgtcttccttctctctggactcggtggccagaaacccgcag
gagctctggcgtttcctgacgcaaaacttgtcgctgcccaatagcacggcccaagcactc
ttggccgcccgtgtggacccgcccgaggtctaccacctgctctttggtccctcatctgcc
ctggattcacagtctggcctccacaagggtcaggagccctggagccgcctagggggcaat
cccctgttccggatggaggagctgctgctggctcctgccctcctggagcagctcacctgc
acgccgggctcgggggagctgggccggatcctcactgtgcctgagagtcagaagggagcc
ctgcagggctaccgggatgctgtctgcagtgggcaggctgctgcgcgtgccaggcgcttc
tctgggctgtctgctgagctccggaaccagctggacgtggccaaggtctcccagcagctg
ggcctggatgcccccaacggctcggactcctcgccacaggcgccacccccacggaggctg
caggcgcttctgggggacctgctggatgcccagaaggttctgcaggatgtggatgtcctg
tcggccctggccctgctactgccccagggtgcctgcactggccggacccccggaccccca
gccagtggtgcgggtggggcggccaatggcactggggcaggggcagtcatgggccccaac
gccaccgctgaggagggcgcaccctctgctgcagcactggccaccccggacacgctgcag
ggccagtgctcagccttcgtacagctctgggccggcctgcagcccatcttgtgtggcaac
aaccgcaccattgaacccgaggcgctgcggcggggcaacatgagctccctgggcttcacg
agcaaggagcagcggaacctgggcctcctcgtgcacctcatgaccagcaaccccaaaatc
ctgtacgcgcctgcgggctctgaggtcgaccgcgtcatcctcaaggccaacgagactttt
gcttttgtgggcaacgtgactcactatgcccaggtctggctcaacatctcggcggagatc
cgcagcttcctggagcagggcaggctgcagcaacacctgcgctggctgcagcagtatgta
gcagagctgcggctgcaccccgaggcactgaacctgtcactggatgagctgccgccggcc
ctgagacaggacaacttctcgctgcccagtggcatggccctcctgcagcagctggatacc
attgacaacgcggcctgcggctggatccagttcatgtccaaggtgagcgtggacatcttc
aagggcttccccgacgaggagagcattgtcaactacaccctcaaccaggcctaccaggac
aacgtcactgtttttgccagtgtgatcttccagacccggaaggacggctcgctcccgcct
cacgtgcactacaagatccgccagaactccagcttcaccgagaaaaccaacgagatccgc
cgcgcctactggcggcctgggcccaatactggcggccgcttctacttcctctacggcttc
gtctggatccaggacatgatggagcgcgccatcatcgacacttttgtggggcacgatgtg
gtggagccaggcagctacgtgcagatgttcccctacccctgctacacacgcgatgacttc
ctgtttgtcattgagcacatgatgccgctgtgcatggtgatctcctgggtctactccgtg
gccatgaccatccagcacatcgtggcggagaaggagcaccggctcaaggaggtgatgaag
accatgggcctgaacaacgcggtgcactgggtggcctggttcatcaccggctttgtgcag
ctgtccatctccgtgacagcactcaccgccatcctgaagtacggccaggtgcttatgcac
agccacgtggtcatcatctggctcttcctggcagtctacgcggtggccaccatcatgttc
tgcttcctggtgtctgtgctgtactccaaggccaagctggcctcggcctgcggtggcatc
atctacttcctgagctacgtgccctacatgtacgtggcgatccgagaggaggtggcgcat
gataagatcacggccttcgagaagtgcatcgcgtccctcatgtccacgacggcctttggt
ctgggctctaagtacttcgcgctgtatgaggtggccggcgtgggcatccagtggcacacc
ttcagccagtccccggtggagggggacgacttcaacttgctcctggctgtcaccatgctg
atggtggacgccgtggtctatggcatcctcacgtggtacattgaggctgtgcacccaggc
atgtacgggctgccccggccctggtacttcccactgcagaagtcctactggctgggcagt
gggcggacagaagcctgggagtggagctggccgtgggcacgcaccccccgcctcagtgtc
atggaggaggaccaggcctgtgccatggagagccggcgctttgaggagacccgtggcatg
gaggaggagcccacccacctgcctctggttgtctgcgtggacaaactcaccaaggtctac
aaggacgacaagaagctggccctgaacaagctgagcctgaacctctacgagaaccaggtg
gtctccttcttgggccacaacggggcgggcaagaccaccaccatgtccatcctgaccggc
ctgttccctccaacgtcgggttccgccaccatctacgggcacgacatccgcacggagatg
gatgagatccgcaagaacctgggcatgtgcccgcagcacaatgtgctctttgaccggctc
acggtggaggaacacctctggttctactcacggctcaagagcatggctcaggaggagatc
cgcagagagatggacaagatgatcgaggacctggagctctccaacaaacggcactcactg
gtgcagacattgtcgggtggcatgaagcgcaagctgtccgtggccatcgccttcgtgggc
ggctctcgcgccatcatcctggacgagcccacggcgggcgtggacccctacgcgcgccgc
gccatctgggacctcatcctgaagtacaagccaggccgcaccatccttctgtccacccac
cacatggatgaggctgacctgcttggggaccgcattgccatcatctcccatgggaagctc
aagtgctgcggctccccgctcttcctcaagggcacctatggcgacgggtaccgcctcacg
ctggtcaagcggcccgccgagccggggggcccccaagagccagggctggcatccagcccc
ccaggtcgggccccgctgagcagctgctccgagctccaggtgtcccagttcatccgcaag
catgtggcctcctgcctgctggtctcagacacaagcacggagctctcctacatcctgccc
agcgaggccgccaagaagggggctttcgagcgcctcttccagcacctggagcgcagcctg
gatgcactgcacctcagcagcttcgggctgatggacacgaccctggaggaagtgttcctc
aaggtgtcggaggaggatcagtcgctggagaacagtgaggccgatgtgaaggagtccagg
aaggatgtgctccctggggcggagggcccggcgtctggggagggtcacgctggcaatctg
gcccggtgctcggagctgacccagtcgcaggcatcgctgcagtcggcgtcatctgtgggc
tctgcccgtggcgacgagggagctggctacaccgacgtctatggcgactaccgccccctc
tttgataacccacaggacccagacaatgtcagcctgcaagaggtggaggcagaggccctg
tcgagggtcggccagggcagccgcaagctggacggcgggtggctgaaggtgcgccagttc
cacgggctgctggtcaaacgcttccactgcgcccgccgcaactccaaggcactcttctcc
cagatcttgctgccagccttcttcgtctgcgtggccatgaccgtggccctgtccgtcccg
gagattggtgatctgcccccgctggtcctgtcaccttcccagtaccacaactacacccag
ccccgtggcaatttcatcccctacgccaacgaggagcgccgcgagtaccggctgcggcta
tcgcccgacgccagcccccagcagctcgtgagcacgttccggctgccgtcgggggtgggt
gccacctgcgtgctcaagtctcccgccaacggctcgctggggcccacgttgaacctgagc
agcggggagtcgcgcctgctggcggctcggttcttcgacagcatgtgtctggagtccttc
acacaggggctgccactgtccaatttcgtgccacccccaccctcgcccgccccatctgac
tcgccagcgtccccggatgaggacctgcaggcctggaacgtctccctgccgcccaccgct
gggccagaaatgtggacgtcggcaccctccctgccgcgcctggtacgggagcccgtccgc
tgcacctgctctgcgcagggcaccggcttctcctgccccagcagtgtgggcgggcacccg
ccccagatgcgggtggtcacaggcgacatcctgaccgacatcaccggccacaatgtctct
gagtacctgctcttcacctccgaccgcttccgactgcaccggtatggggccatcaccttt
ggaaacgtcctgaagtccatcccagcctcatttggcaccagggccccacccatggtgcgg
aagatcgcggtgcgcagggctgcccaggttttctacaacaacaagggctatcacagcatg
cccacctacctcaacagcctcaacaacgccatcctgcgtgccaacctgcccaagagcaag
ggcaacccggcggcttacggcatcaccgtcaccaaccaccccatgaataagaccagcgcc
agcctctccctggattacctgctgcagggcacggatgtcgtcatcgccatcttcatcatc
gtggccatgtccttcgtgccggccagcttcgttgtcttcctcgtggccgagaagtccacc
aaggccaagcacctgcagtttgtcagcggctgcaaccccatcatctactggctggcgaac
tacgtgtgggacatgctcaactacctggtccccgctacctgctgtgtcatcatcctgttt
gtgttcgacctgccggcctacacgtcgcccaccaacttccctgccgtcctctccctcttc
ctgctctatgggtggtccatcacgcccatcatgtacccggcctccttctggttcgaggtc
cccagctccgcctacgtgttcctcattgtcatcaatctcttcatcggcatcaccgccacc
gtggccaccttcctgctacagctcttcgagcacgacaaggacctgaaggttgtcaacagt
tacctgaaaagctgcttcctcattttccccaactacaacctgggccacgggctcatggag
atggcctacaacgagtacatcaacgagtactacgccaagattggccagtttgacaagatg
aagtccccgttcgagtgggacattgtcacccgcggactggtggccatggcggttgagggc
gtcgtgggcttcctcctgaccatcatgtgccagtacaacttcctgcggcggccacagcgc
atgcctgtgtctaccaagcctgtggaggatgatgtggacgtggccagtgagcggcagcga
gtgctccggggagacgccgacaatgacatggtcaagattgagaacctgaccaaggtctac
aagtcccggaagattggccgtatcctggccgttgaccgcctgtgcctgggtgtgcgtcct
ggcgagtgcttcgggctcctgggcgtcaacggtgcgggcaagaccagcaccttcaagatg
ctgaccggcgacgagagcacgacggggggcgaggccttcgtcaatggacacagcgtgctg
aaggagctgctccaggtgcagcagagcctcggctactgcccgcagtgtgacgcgctgttc
gacgagctcacggcccgggagcacctgcagctgtacacgcggctgcgtgggatctcctgg
aaggacgaggcccgggtggtgaagtgggctctggagaagctggagctgaccaagtacgca
gacaagccggctggcacctacagcggcggcaacaagcggaagctctccacggccatcgcc
ctcattgggtacccagccttcatcttcctggacgagcccaccacaggcatggaccccaag
gcccggcgcttcctctggaacctcatccttgacctcatcaagacagggcgttcagtggtg
ctgacatcacacagcatggaggagtgcgaggcgctgtgcacgcggctggccatcatggtg
aacggtcgcctgcggtgcctgggcagcatccagcacctgaagaaccggtttggagatggc
tacatgatcacggtgcggaccaagagcagccagagtgtgaaggacgtggtgcggttcttc
aaccgcaacttcccggaagccatgctcaaggagcggcaccacacaaaggtgcagtaccag
ctcaagtcggagcacatctcgctggcccaggtgttcagcaagatggagcaggtgtctggc
gtgctgggcatcgaggactactcggtcagccagaccacactggacaatgtgttcgtgaac
tttgccaagaagcagagtgacaacctggagcagcaggagacggagccgccatccgcactg
cagtcccctctcggctgcttgctcagcctgctccggccccggtctgcccccacggagctc
cgggcacttgtggcagacgagcccgaggacctggacacggaggacgagggcctcatcagc
ttcgaggaggagcgggcccagctgtccttcaacacggacacgctctgctga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (13)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (64)   
   RefSeq(nuc) (2)   
   GenBank (31)   
   EMBL (31)   
Protein domain (6)   
   Pfam (6)   
All databases (98)   

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