KEGG T01001: 2052

Homo sapiens (human): 2052

Entry

2052 CDS T01001

Gene name

EPHX1, EPHX, EPOX, HYL1, MEH

Definition

epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9)

Orthology

K01253

microsomal epoxide hydrolase [EC:3.3.2.9]

Organism

hsa Homo sapiens (human)

Pathway

hsa00980	Metabolism of xenobiotics by cytochrome P450
hsa04976	Bile secretion
hsa05204	Chemical carcinogenesis

Disease

H00516

Isolated orofacial clefts

Class

Metabolism; Xenobiotics biodegradation and metabolism; Metabolism of xenobiotics by cytochrome P450 [PATH:hsa00980]
Organismal Systems; Digestive system; Bile secretion [PATH:hsa04976]
Human Diseases; Cancers; Chemical carcinogenesis [PATH:hsa05204]

SSDB

Motif

Pfam:

EHN Abhydrolase_1 Abhydrolase_6

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

1q42.1

AA seq 455 aa
MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRPFKVETSDEEI
HDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKI
EGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEV
ICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVP
SHVKGLHLNMALVLSNFSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYM
HIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVML
YWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSAFPFELLHTPEKWVRFKYPKL
ISYSYMVRGGHFAAFEEPELLAQDIRKFLSVLERQ

NT seq 1368 nt +upstreamnt +downstreamnt
atgtggctagaaatcctcctcacttcagtgctgggctttgccatctactggttcatctcc
cgggacaaagaggaaactttgccacttgaagatgggtggtgggggccaggcacgaggtcc
gcagccagggaggacgacagcatccgccctttcaaggtggaaacgtcagatgaggagatc
cacgacttacaccagaggatcgataagttccgtttcaccccacctttggaggacagctgc
ttccactatggcttcaactccaactacctgaagaaagtcatctcctactggcggaatgaa
tttgactggaagaagcaggtggagattctcaacagataccctcacttcaagactaagatt
gaagggctggacatccacttcatccacgtgaagcccccccagctgcccgcaggccatacc
ccgaagcccttgctgatggtgcacggctggcccggctctttctacgagttttataagatc
atcccactcctgactgaccccaagaaccatggcctgagcgatgagcacgtttttgaagtc
atctgcccttccatccctggctatggcttctcagaggcatcctccaagaaggggttcaac
tcggtggccaccgccaggatcttttacaagctgatgctgcggctgggcttccaggaattc
tacattcaaggaggggactgggggtccctgatctgcactaatatggcccagctggtgccc
agccacgtgaaaggcctgcacttgaacatggctttggttttaagcaacttctctaccctg
accctcctcctgggacagcgtttcgggaggtttcttggcctcactgagagggatgtggag
ctgctgtaccccgtcaaggagaaggtattctacagcctgatgagggagagcggctacatg
cacatccagtgcaccaagcctgacaccgtaggctctgctctgaatgactctcctgtgggt
ctggctgcctatattctagagaagttttccacctggaccaatacggaattccgatacctg
gaggatggaggcctggaaaggaagttctccctggacgacctgctgaccaacgtcatgctc
tactggacaacaggcaccatcatctcctcccagcgcttctacaaggagaacctgggacag
ggctggatgacccagaagcatgagcggatgaaggtctatgtgcccactggcttctctgcc
ttcccttttgagctattgcacacgcctgaaaagtgggtgaggttcaagtacccaaagctc
atctcctattcctacatggttcgtgggggccactttgcggcctttgaggagccggagctg
ctcgcccaggacatccgcaagttcctgtcggtgctggagcggcaatga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (10)   
   KEGG ENZYME (1)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (14)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (32)   
   RefSeq(nuc) (2)   
   GenBank (15)   
   EMBL (15)   
Protein domain (3)   
   Pfam (3)   
All databases (97)   

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