KEGG   Homo sapiens (human): 2065Help
Entry
2065              CDS       T01001                                 

Gene name
ERBB3, ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3
Definition
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1)
Orthology
K05084  
receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
ErbB signaling pathway
Calcium signaling pathway
Endocytosis
Proteoglycans in cancer
MicroRNAs in cancer
Disease
H00408  
Type I diabetes mellitus
H00865  
Lethal congenital contractural syndrome (LCCS)
Drug target
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    2065 (ERBB3)
   04020 Calcium signaling pathway
    2065 (ERBB3)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    2065 (ERBB3)
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    2065 (ERBB3)
   05205 Proteoglycans in cancer
    2065 (ERBB3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2065 (ERBB3)
Protein kinases [BR:hsa01001]
 Tyrosine protein kinases
  EGFR family [OT]
   2065 (ERBB3)
Enzyme-linked receptors [BR:hsa01020]
 Receptor tyrosine kinases
  RTK class I (EGF receptor family)
   2065 (ERBB3)
Cytokine receptors [BR:hsa04050]
 Receptor tyrosine kinase
  RTK class I (EGF receptor family)
   2065 (ERBB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
12q13
AA seq 183 aa AA seqDB search
MRANDALQVLGLLFSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRLTQLTGQFPMVPSGLTPQPAQDWYLLDDDPRLLTLSASSKVPVTL
AAV
NT seq 552 nt NT seq  +upstreamnt  +downstreamnt
atgagggcgaacgacgctctgcaggtgctgggcttgcttttcagcctggcccggggctcc
gaggtgggcaactctcaggcagtgtgtcctgggactctgaatggcctgagtgtgaccggc
gatgctgagaaccaataccagacactgtacaagctctacgagaggtgtgaggtggtgatg
gggaaccttgagattgtgctcacgggacacaatgccgacctctccttcctgcagtggatt
cgagaagtgacaggctatgtcctcgtggccatgaatgaattctctactctaccattgccc
aacctccgcgtggtgcgagggacccaggtctacgatgggaagtttgccatcttcgtcatg
ttgaactataacaccaactccagccacgctctgcgccagctccgcttgactcagctcacc
ggtcagttcccgatggttccttctggcctcacccctcagccagcccaagactggtacctc
cttgatgatgacccaagactgctcactctaagtgcctcttccaaggtgcctgtcaccttg
gccgctgtctaa

DBGET integrated database retrieval system