| Entry |
|
|---|
| Gene name |
ALAS1, ALAS, ALAS3, ALASH, MIG4
|
|---|
| Definition |
aminolevulinate, delta-, synthase 1 (EC:2.3.1.37)
|
|---|
| Orthology |
| 5-aminolevulinate synthase [EC: 2.3.1.37] |
|
|---|
| Organism |
|
|---|
| Pathway |
| Glycine, serine and threonine metabolism | | Porphyrin and chlorophyll metabolism | | Metabolic pathways |
|
|---|
| Class |
Metabolism; Amino acid metabolism; Glycine, serine and threonine metabolism [PATH: hsa00260]
Metabolism; Metabolism of cofactors and vitamins; Porphyrin and chlorophyll metabolism [PATH: hsa00860]
 |
|---|
| SSDB |
   |
|---|
| Motif |
 |
|---|
| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
|---|
| Position |
3p21.1
|
|---|
| AA seq |
640 aa  
MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKE
TPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGS
SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPE
RVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLI
TKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADL
HGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHND
VSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYG
ARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPM
LLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKN
TEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLE
LKPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA |
|---|
| NT seq |
1923 nt  +upstreamnt +downstreamnt
atggagagtgttgttcgccgctgcccattcttatcccgagtcccccaggcctttctgcag
aaagcaggcaaatctctgttgttctatgcccaaaactgccccaagatgatggaagttggg
gccaagccagcccctcgggcattgtccactgcagcagtacactaccaacagatcaaagaa
acccctccggccagtgagaaagacaaaactgctaaggccaaggtccaacagactcctgat
ggatcccagcagagtccagatggcacacagcttccgtctggacaccccttgcctgccaca
agccagggcactgcaagcaaatgccctttcctggcagcacagatgaatcagagaggcagc
agtgtcttctgcaaagccagtcttgagcttcaggaggatgtgcaggaaatgaatgccgtg
aggaaagaggttgctgaaacctcagcaggccccagtgtggttagtgtgaaaaccgatgga
ggggatcccagtggactgctgaagaacttccaggacatcatgcaaaagcaaagaccagaa
agagtgtctcatcttcttcaagataacttgccaaaatctgtttccacttttcagtatgat
cgtttctttgagaaaaaaattgatgagaaaaagaatgaccacacctatcgagtttttaaa
actgtgaaccggcgagcacacatcttccccatggcagatgactattcagactccctcatc
accaaaaagcaagtgtcagtctggtgcagtaatgactacctaggaatgagtcgccaccca
cgggtgtgtggggcagttatggacactttgaaacaacatggtgctggggcaggtggtact
agaaatatttctggaactagtaaattccatgtggacttagagcgggagctggcagacctc
catgggaaagatgccgcactcttgttttcctcgtgctttgtggccaatgactcaaccctc
ttcaccctggctaagatgatgccaggctgtgagatttactctgattctgggaaccatgcc
tccatgatccaagggattcgaaacagccgagtgccaaagtacatcttccgccacaatgat
gtcagccacctcagagaactgctgcaaagatctgacccctcagtccccaagattgtggca
tttgaaactgtccattcaatggatggggcggtgtgcccactggaagagctgtgtgatgtg
gcccatgagtttggagcaatcaccttcgtggatgaggtccacgcagtggggctttatggg
gctcgaggcggagggattggggatcgggatggagtcatgccaaaaatggacatcatttct
ggaacacttggcaaagcctttggttgtgttggagggtacatcgccagcacgagttctctg
attgacaccgtacggtcctatgctgctggcttcatcttcaccacctctctgccacccatg
ctgctggctggagccctggagtctgtgcggatcctgaagagcgctgagggacgggtgctt
cgccgccagcaccagcgcaacgtcaaactcatgagacagatgctaatggatgccggcctc
cctgttgtccactgccccagccacatcatccctgtgcgggttgcagatgctgctaaaaac
acagaagtctgtgatgaactaatgagcagacataacatctacgtgcaagcaatcaattac
cctacggtgccccggggagaagagctcctacggattgcccccacccctcaccacacaccc
cagatgatgaactacttccttgagaatctgctagtcacatggaagcaagtggggctggaa
ctgaagcctcattcctcagctgagtgcaacttctgcaggaggccactgcattttgaagtg
atgagtgaaagagagaagtcctatttctcaggcttgagcaagttggtatctgctcaggcc
tga |
|---|
