KEGG T01001: 2122

Homo sapiens (human): 2122

Entry

2122 CDS T01001

Gene name

MECOM, AML1-EVI-1, EVI1, MDS1, MDS1-EVI1, PRDM3

Definition

MDS1 and EVI1 complex locus

Orthology

K04462

ecotropic virus integration site 1 protein

Organism

hsa Homo sapiens (human)

Pathway

hsa04010	MAPK signaling pathway
hsa05200	Pathways in cancer
hsa05220	Chronic myeloid leukemia

Disease

H00004

Chronic myeloid leukemia (CML)

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:hsa04010]
Human Diseases; Cancers; Pathways in cancer [PATH:hsa05200]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:hsa05220]

SSDB

Motif

Pfam:

zf-C2H2 zf-H2C2_2 zf-C2H2_4 zf-C2H2_6 zf-C2H2_jaz zf-BED UPF0547

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

3q26.2

AA seq 1116 aa
MILDEFYNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIAPGEE
LLLFMKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEE
DFQQKLESENDLQEIHTIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKS
NLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGL
KQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKH
RRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPT
APGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILK
ALSKHPSVGDNKPVELQPERSSEERPFEKISDQSESSDLDDVSTPSGSDLETTSGSDLES
DIESDKEKFKENGKMFKDKVSPLQNLASINNKKEYSNHSIFSPSLEEQTAVSGAVNDSIK
AIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKME
PQSPGEVKKLQKGSSESPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRA
SGTKLTEPRKNHVFGGKKGSNVESRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEAL
KEKYLRPSPGFLFHPQFQLPDQRTWMSAIENMAEKLESFSALKPEASELLQSVPSMFNFR
APPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSN
LQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAI
LDDKEDAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVED
EVLLDEEDEDNDITGKTGKEPVTSNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSG
LSALDHIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSL
SDKESLHSTSHSSSNVWHSMARAAAESSAIQSISHV

NT seq 3351 nt +upstreamnt +downstreamnt
atgatcttagacgaattttacaatgtgaagttctgcatagatgccagtcaaccagatgtt
ggaagctggctcaagtacattagattcgctggctgttatgatcagcacaaccttgttgca
tgccagataaatgatcagatattctatagagtagttgcagacattgcgccgggagaggag
cttctgctgttcatgaagagcgaagactatccccatgaaactatggcgccggatatccac
gaagaacggcaatatcgctgcgaagactgtgaccagctctttgaatctaaggctgaacta
gcagatcaccaaaagtttccatgcagtactcctcactcagcattttcaatggttgaagag
gactttcagcaaaaactcgaaagcgagaatgatctccaagagatacacacgatccaggag
tgtaaggaatgtgaccaagtttttcctgatttgcaaagcctggagaaacacatgctgtca
catactgaagagagggaatacaagtgtgatcagtgtcccaaggcatttaactggaagtcc
aatttaattcgccaccagatgtcacatgacagtggaaagcactatgaatgtgaaaactgt
gccaagcaggttttcacggaccctagcaaccttcagcggcacattcgctctcagcatgtc
ggtgcccgggcccatgcatgcccggagtgtggcaaaacgtttgccacttcgtcgggcctc
aaacaacacaagcacatccacagcagtgtgaagccctttatctgtgaggtctgccataaa
tcctatactcagttttcaaacctttgccgtcataagcgcatgcatgctgattgcagaacc
caaatcaagtgcaaagactgtggacaaatgttcagcactacgtcttccttaaataaacac
aggaggttttgtgagggcaagaaccattttgcggcaggtggattttttggccaaggcatt
tcacttcctggaaccccagctatggataaaacgtccatggttaatatgagtcatgccaac
ccgggccttgctgactattttggcgccaataggcatcctgctggtcttacctttccaaca
gctcctggattttcttttagcttccctggtctgtttccttccggcttgtaccacaggcct
cctttgatacctgctagttctcctgttaaaggactatcaagtactgaacagacaaacaaa
agtcaaagtcccctcatgacacatcctcagatactgccagctacacaggatattttgaag
gcactatctaaacacccatctgtaggggacaataagccagtggagctccagcccgagagg
tcctctgaagagaggccctttgagaaaatcagtgaccagtcagagagtagtgaccttgat
gatgtcagtacaccaagtggcagtgacctggaaacaacctcgggctctgatctggaaagt
gacattgaaagtgataaagagaaatttaaagaaaatggtaaaatgttcaaagacaaagta
agccctcttcagaatctggcttcaataaataataagaaagaatacagcaatcattccatt
ttctcaccatctttagaggagcagactgcggtgtcaggagctgtgaatgattctataaag
gctattgcttctattgctgaaaaatactttggttcaacaggactggtggggctgcaagac
aaaaaagttggagctttaccttacccttccatgtttcccctcccattttttccagcattc
tctcaatcaatgtacccatttcctgatagagacttgagatcgttacctttgaaaatggaa
ccccaatcaccaggtgaagtaaagaaactgcagaagggcagctctgagtccccctttgat
ctcaccactaagcgaaaggatgagaagcccttgactccagtcccctccaagcctccagtg
acacctgccacaagccaagaccagcccctggatctaagtatgggcagtaggagtagagcc
agtgggacaaagctgactgagcctcgaaaaaaccacgtgtttgggggaaaaaaaggaagc
aacgtcgaatcaagacctgcttcagatggttccttgcagcatgcaagacccactcctttc
tttatggaccctatttacagagtagagaaaagaaaactaactgacccacttgaagcttta
aaagagaaatacttgaggccttctccaggattcttgtttcacccacaattccaactgcct
gatcagagaacttggatgtcagctattgaaaacatggcagaaaagctagagagcttcagt
gccctgaaacctgaggccagtgagctcttacagtcagtgccctctatgttcaacttcagg
gcgcctcccaatgccctgccagagaaccttctgcggaagggaaaggagcgctatacctgc
agatactgtggcaagatttttccaaggtctgcaaacctaacacggcacttgagaacccac
acaggagagcagccttacagatgcaaatactgtgacagatcatttagcatatcttctaac
ttgcaaaggcatgttcgcaacatccacaataaagagaagccatttaagtgtcacttatgt
gataggtgttttggtcaacaaaccaatttagacagacacctaaagaaacatgagaatggg
aacatgtccggtacagcaacatcgtcgcctcattctgaactggaaagtacaggtgcgatt
ctggatgacaaagaagatgcttacttcacagaaattcgaaatttcattgggaacagcaac
catggcagccaatctcccaggaatgtggaggagagaatgaatggcagtcattttaaagat
gaaaaggctttggtgaccagtcaaaattcagacttgctggatgatgaagaagttgaagat
gaggtgttgttagatgaggaggatgaagacaatgatattactggaaaaacaggaaaggaa
ccagtgacaagtaatttacatgaaggaaaccctgaggatgactatgaagaaaccagtgcc
ctggagatgagttgcaagacatccccagtgaggtataaagaggaagaatataaaagtgga
ctttctgctctagatcatataaggcacttcacagatagcctcaaaatgaggaaaatggaa
gataatcaatattctgaagctgagctgtcttcttttagtacttcccatgtgccagaggaa
cttaagcagccgttacacagaaagtccaaatcgcaggcatatgctatgatgctgtcactg
tctgacaaggagtccctccattctacatcccacagttcttccaacgtgtggcacagtatg
gccagggctgcggcggaatccagtgctatccagtccataagccacgtatga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (26)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (3)   
   RefSeq(pep) (7)   
DNA sequence (75)   
   RefSeq(nuc) (7)   
   GenBank (34)   
   EMBL (34)   
Protein domain (7)   
   Pfam (7)   
All databases (134)   

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