KEGG   Homo sapiens (human): 2159Help
Entry
2159              CDS       T01001                                 

Gene name
F10, FX, FXA
Definition
(RefSeq) coagulation factor X (EC:3.4.21.6)
  KO
K01314  
coagulation factor X [EC:3.4.21.6]
Organism
hsa  Homo sapiens (human)
Pathway
Complement and coagulation cascades
Drug target
Rivaroxaban: 
Apixaban: 
Fondaparinux: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Immune system
   04610 Complement and coagulation cascades
    2159 (F10)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.6  coagulation factor Xa
     2159 (F10)
Peptidases [BR:hsa01002]
 Serine Peptidases
  Family S1: chymotrypsin family
   2159 (F10)
Cell adhesion molecules and their ligands [BR:hsa04516]
 2. Integrin Family
  Beta2 integrins
   CR3, Mac-1
    ITGB2; integrin beta 2 [KO:K06464]
     2159 (F10)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Coagulation and fibrinolysis (General comment) Coagulation, inflammation, complement control
   2159 (F10)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
13q34
AA seq 488 aa AA seqDB search
MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
NT seq 1467 nt NT seq  +upstreamnt  +downstreamnt
atggggcgcccactgcacctcgtcctgctcagtgcctccctggctggcctcctgctgctc
ggggaaagtctgttcatccgcagggagcaggccaacaacatcctggcgagggtcacgagg
gccaattcctttcttgaagagatgaagaaaggacacctcgaaagagagtgcatggaagag
acctgctcatacgaagaggcccgcgaggtctttgaggacagcgacaagacgaatgaattc
tggaataaatacaaagatggcgaccagtgtgagaccagtccttgccagaaccagggcaaa
tgtaaagacggcctcggggaatacacctgcacctgtttagaaggattcgaaggcaaaaac
tgtgaattattcacacggaagctctgcagcctggacaacggggactgtgaccagttctgc
cacgaggaacagaactctgtggtgtgctcctgcgcccgcgggtacaccctggctgacaac
ggcaaggcctgcattcccacagggccctacccctgtgggaaacagaccctggaacgcagg
aagaggtcagtggcccaggccaccagcagcagcggggaggcccctgacagcatcacatgg
aagccatatgatgcagccgacctggaccccaccgagaaccccttcgacctgcttgacttc
aaccagacgcagcctgagaggggcgacaacaacctcaccaggatcgtgggaggccaggaa
tgcaaggacggggagtgtccctggcaggccctgctcatcaatgaggaaaacgagggtttc
tgtggtggaaccattctgagcgagttctacatcctaacggcagcccactgtctctaccaa
gccaagagattcaaggtgagggtaggggaccggaacacggagcaggaggagggcggtgag
gcggtgcacgaggtggaggtggtcatcaagcacaaccggttcacaaaggagacctatgac
ttcgacatcgccgtgctccggctcaagacccccatcaccttccgcatgaacgtggcgcct
gcctgcctccccgagcgtgactgggccgagtccacgctgatgacgcagaagacggggatt
gtgagcggcttcgggcgcacccacgagaagggccggcagtccaccaggctcaagatgctg
gaggtgccctacgtggaccgcaacagctgcaagctgtccagcagcttcatcatcacccag
aacatgttctgtgccggctacgacaccaagcaggaggatgcctgccagggggacagcggg
ggcccgcacgtcacccgcttcaaggacacctacttcgtgacaggcatcgtcagctgggga
gagggctgtgcccgtaaggggaagtacgggatctacaccaaggtcaccgccttcctcaag
tggatcgacaggtccatgaaaaccaggggcttgcccaaggccaagagccatgccccggag
gtcataacgtcctctccattaaagtga

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