KEGG T01001: 2160

Homo sapiens (human): 2160

Entry

2160 CDS T01001

Gene name

F11, FXI

Definition

coagulation factor XI (EC:3.4.21.27)

Orthology

K01323

coagulation factor XI [EC:3.4.21.27]

Organism

hsa Homo sapiens (human)

Pathway

hsa04610

Complement and coagulation cascades

Disease

H00938

Factor XI deficiency

Class

Organismal Systems; Immune system; Complement and coagulation cascades [PATH:hsa04610]

SSDB

Motif

Pfam:

Trypsin PAN_1 PAN_4 DUF1986 Trypsin_2 PAN_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

UniProt:

Structure

PDB:

3BG8 1ZHR 3SOR 1ZSJ 1ZSK 1ZHM 2FDA 1ZMJ 1ZTJ 1ZSL 1ZMN 1ZPB 1XX9 1ZOM 1ZML 1ZRK 1ZTK 1ZPZ 1ZLR 3SOS 1ZTL 1ZPC 1ZJD 1XXF 1ZHP 2F83 1XXD 2J8J 2J8L

Position

4q35

AA seq 625 aa
MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFT
FTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDM
KGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITK
LDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFT
FFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTD
FLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKIL
HGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSI
IGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYD
IALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLV
TNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCA
QRERPGVYTNVVEYVDWILEKTQAV

NT seq 1878 nt +upstreamnt +downstreamnt
atgattttcttatatcaagtggtacatttcattttatttacttcagtttctggtgaatgt
gtgactcagttgttgaaggacacctgctttgaaggaggggacattactacggtcttcaca
ccaagcgccaagtactgccaggtagtctgcacttaccacccaagatgtttactcttcact
ttcacggcggaatcaccatctgaggatcccacccgatggtttacttgtgtcctgaaagac
agtgttacagaaacactgccaagagtgaataggacagcagcgatttctgggtattctttc
aagcaatgctcacaccaaataagcgcttgcaacaaagacatttatgtggacctagacatg
aagggcataaactataacagctcagttgccaagagtgctcaagaatgccaagaaagatgc
acggatgacgtccactgccactttttcacgtacgccacaaggcagtttcccagcctggag
catcgtaacatttgtctactgaagcacacccaaacagggacaccaaccagaataacgaag
ctcgataaagtggtgtctggattttcactgaaatcctgtgcactttctaatctggcttgt
attagggacattttccctaatacggtgtttgcagacagcaacatcgacagtgtcatggct
cccgatgcttttgtctgtggccgaatctgcactcatcatcccggttgcttgttttttacc
ttcttttcccaggaatggcccaaagaatctcaaagaaatctttgtctccttaaaacatct
gagagtggattgcccagtacacgcattaaaaagagcaaagctctttctggtttcagtcta
caaagctgcaggcacagcatcccagtgttctgccattcttcattttaccatgacactgat
ttcttgggagaagaactggatattgttgctgcaaaaagtcacgaggcctgccagaaactg
tgcaccaatgccgtccgctgccagttttttacctataccccagcccaagcatcctgcaac
gaagggaagggcaagtgttacttaaagctttcttcaaacggatctccaactaaaatactt
cacgggagaggaggcatctctggatacacattaaggttgtgtaaaatggataatgagtgt
accaccaaaatcaagcccaggatcgttggaggaactgcgtctgttcgtggtgagtggccg
tggcaggtgaccctgcacacaacctcacccactcagagacacctgtgtggaggctccatc
attggaaaccagtggatattaacagccgctcactgtttctatggggtagagtcacctaag
attttgcgtgtctacagtggcattttaaatcaatctgaaataaaagaggacacatctttc
tttggggttcaagaaataataatccatgatcagtataaaatggcagaaagcgggtatgat
attgccttgttgaaactggaaaccacagtgaattacacagattctcaacgacccatatgc
ctgccttccaaaggagatagaaatgtaatatacactgattgctgggtgactggatggggg
tacagaaaactaagagacaaaatacaaaatactctccagaaagccaagatacccttagtg
accaacgaagagtgccagaagagatacagaggacataaaataacccataagatgatctgt
gccggctacagggaaggagggaaggacgcttgcaagggagattcgggaggccctctgtcc
tgcaaacacaatgaggtctggcatctggtaggcatcacgagctggggcgaaggctgtgct
caaagggagcggccaggtgtttacaccaacgtggtcgagtacgtggactggattctggag
aaaactcaagcagtgtga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (18)   
   RefSeq(nuc) (2)   
   GenBank (8)   
   EMBL (8)   
3D Structure (29)   
   PDB (29)   
Protein domain (6)   
   Pfam (6)   
All databases (74)   

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