| Entry |
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| Gene name |
ACSL1, ACS1, FACL1, FACL2, LACS, LACS1, LACS2
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| Definition |
acyl-CoA synthetase long-chain family member 1 (EC:6.2.1.3)
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| Orthology |
| long-chain acyl-CoA synthetase [EC: 6.2.1.3] |
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| Organism |
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| Pathway |
| Fatty acid metabolism | | Metabolic pathways | | PPAR signaling pathway | | Peroxisome | | Adipocytokine signaling pathway |
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| Module |
| beta-Oxidation, acyl-CoA synthesis |
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| Class |
Metabolism; Lipid metabolism; Fatty acid metabolism [PATH: hsa00071]
Cellular Processes; Transport and catabolism; Peroxisome [PATH: hsa04146]
Organismal Systems; Endocrine system; Adipocytokine signaling pathway [PATH: hsa04920]
Organismal Systems; Endocrine system; PPAR signaling pathway [PATH: hsa03320]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Position |
4q35
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| AA seq |
698 aa  
MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQ
SVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW
LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT
LGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQR
CGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAF
VKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQP
TVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKV
QSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHV
GAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD
IGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAI
VVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHP
ELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYSTIKV |
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| NT seq |
2097 nt  +upstreamnt +downstreamnt
atgcaagcccatgagctgttccggtattttcgaatgccagagctggttgacttccgacag
tacgtgcgtactcttccgaccaacacgcttatgggcttcggagcttttgcagcactcacc
accttctggtacgccacgagacccaaacccctgaagccgccatgcgacctctccatgcag
tcagtggaagtggcgggtagtggtggtgcacgaagatccgcactacttgacagcgacgag
cccttggtgtatttctatgatgatgtcacaacattatacgaaggtttccagaggggaata
caggtgtcaaataatggcccttgtttaggctctcggaaaccagaccaaccctatgaatgg
ctttcatataaacaggttgcagaattgtcggagtgcataggctcagcactgatccagaag
ggcttcaagactgccccagatcagttcattggcatctttgctcaaaatagacctgagtgg
gtgattattgaacaaggatgctttgcttattcgatggtgatcgttccactttatgatacc
cttggaaatgaagccatcacgtacatagtcaacaaagctgaactctctctggtttttgtt
gacaagccagagaaggccaaactcttattagagggtgtagaaaataagttaataccaggc
cttaaaatcatagttgtcatggatgcctacggcagtgaactggtggaacgaggccagagg
tgtggggtggaagtcaccagcatgaaggcgatggaggacctgggaagagccaacagacgg
aagcccaagcctccagcacctgaagatcttgcagtaatttgtttcacaagtggaactaca
ggcaaccccaaaggagcaatggtcactcaccgaaacatagtgagcgattgttcagctttt
gtgaaagcaacagagaatacagtcaatccttgcccagatgatactttgatatctttcttg
cctctcgcccatatgtttgagagagttgtagagtgtgtaatgctgtgtcatggagctaaa
atcggatttttccaaggagatatcaggctgctcatggatgacctcaaggtgcttcaaccc
actgtcttccccgtggttccaagactgctgaaccggatgtttgaccgaattttcggacaa
gcaaacaccacgctgaagcgatggctcttggactttgcctccaagaggaaagaagcagag
cttcgcagcggcatcatcagaaacaacagcctgtgggaccggctgatcttccacaaagta
cagtcgagcctgggcggaagagtccggctgatggtgacaggagccgccccggtgtctgcc
actgtgctgacgttcctcagagcagccctgggctgtcagttttatgaaggatacggacag
acagagtgcactgccgggtgctgcctgaccatgcctggagactggaccgcaggccatgtt
ggggccccgatgccgtgcaatttgataaaacttgttgatgtggaagaaatgaattacatg
gctgccgagggcgagggcgaggtgtgtgtgaaagggccaaatgtatttcagggctacttg
aaggacccagcgaaaacagcagaagctttggacaaagacggctggttacacacaggggac
attggaaaatggttaccaaatggcaccttgaaaattatcgaccggaaaaagcacatattt
aagctggcacaaggagaatacatagcccctgaaaagattgaaaatatctacatgcgaagt
gagcctgttgctcaggtgtttgtccacggagaaagcctgcaggcatttctcattgcaatt
gtggtaccagatgttgagacattatgttcctgggcccaaaagagaggatttgaagggtcg
tttgaggaactgtgcagaaataaggatgtcaaaaaagctatcctcgaagatatggtgaga
cttgggaaggattctggtctgaaaccatttgaacaggtcaaaggcatcacattgcaccct
gaattattttctatcgacaatggccttctgactccaacaatgaaggcgaaaaggccagag
ctgcggaactatttcaggtcgcagatagatgacctctattccactatcaaggtttag |
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