KEGG   Homo sapiens (human): 2182Help
Entry
2182              CDS       T01001                                 

Gene name
ACSL4, ACS4, FACL4, LACS4, MRX63, MRX68
Definition
acyl-CoA synthetase long-chain family member 4 (EC:6.2.1.3)
Orthology
K01897  
long-chain acyl-CoA synthetase [EC:6.2.1.3]
Organism
hsa  Homo sapiens (human)
Pathway
Fatty acid biosynthesis
Fatty acid degradation
Metabolic pathways
Fatty acid metabolism
PPAR signaling pathway
Peroxisome
Adipocytokine signaling pathway
Module
beta-Oxidation, acyl-CoA synthesis
Disease
H00480  
Non-syndromic X-linked mental retardation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01212 Fatty acid metabolism
    2182 (ACSL4)
  Lipid metabolism
   00061 Fatty acid biosynthesis
    2182 (ACSL4)
   00071 Fatty acid degradation
    2182 (ACSL4)
 Cellular Processes
  Transport and catabolism
   04146 Peroxisome
    2182 (ACSL4)
 Organismal Systems
  Endocrine system
   04920 Adipocytokine signaling pathway
    2182 (ACSL4)
   03320 PPAR signaling pathway
    2182 (ACSL4)
Enzymes [BR:hsa01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.3  long-chain-fatty-acid---CoA ligase
     2182 (ACSL4)
Lipid biosynthesis proteins [BR:hsa01004]
 Acyl-CoA synthetase
  Long/very long chain acyl-CoA synthetase
   2182 (ACSL4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   2182 (ACSL4)
  Exosomal proteins of breast cancer cells
   2182 (ACSL4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
Xq22.3-q23
AA seq 670 aa AA seqDB search
MAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREI
LSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRA
EWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISC
VKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGS
TGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIG
YSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFK
IGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCP
IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVI
GGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE
YVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICN
NPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYL
KDIERMYGGK
NT seq 2013 nt NT seq  +upstreamnt  +downstreamnt
atggcaaagagaataaaagctaagcccacttcagacaaacctggaagtccatatcgctct
gtcacacacttcgactcactagctgtaatagacatccctggagcagatactctggataaa
ttatttgaccatgctgtatccaagtttgggaagaaggacagccttgggaccagggaaatc
ctaagtgaagaaaatgaaatgcagccaaatggaaaagtttttaagaagttaattcttggg
aattataaatggatgaactatcttgaagtgaatcgcagagtgaataactttggtagtgga
ctcactgcactgggactaaaaccaaagaacaccattgccatcttctgtgagaccagggcc
gaatggatgattgcagcacagacctgctttaagtacaactttcctcttgtgactttatat
gccacacttggcaaagaagcagtagttcatgggctaaatgaatctgaggcttcctatctg
attaccagtgttgaacttctggaaagtaaacttaagactgcattgttagatatcagttgt
gttaaacatatcatttatgtggacaataaggctatcaataaagcagagtaccctgaagga
tttgagattcacagcatgcaatcagtagaagagttgggatctaacccagaaaacttgggc
attcctccaagtagaccaacgccttcagacatggccattgttatgtatactagtggttct
actggccgacctaagggagtgatgatgcatcatagcaatttgatagctggaatgacaggc
cagtgtgaaagaatacctggactgggaccgaaggacacatatattggctacttgcctttg
gctcatgtgctagaactgacagcagagatatcttgctttacctatggctgcaggattgga
tattcttctccgcttacactctctgaccagtccagcaaaattaaaaaaggaagcaaagga
gactgtactgtactgaagcccacacttatggctgctgttccggaaatcatggatagaatt
tataagaatgttatgagcaaagtccaagagatgaattatattcagaaaactctgttcaag
atagggtatgattacaaattggaacagatcaaaaagggatatgatgcacctctttgcaat
ctgttactgtttaaaaaggtcaaggccctgctgggagggaatgtccgcatgatgctgtct
ggaggggccccgctatctcctcagacacaccgattcatgaatgtctgcttctgctgccca
attggccagggttatggactgacagaatcatgtggtgctgggacagttactgaagtaact
gactatactactggcagagttggagcacctcttatttgctgtgaaattaagctaaaagac
tggcaagaaggcggttatacaattaatgacaagccaaaccccagaggtgaaatcgtaatt
ggtggacagaacatctccatgggatattttaaaaatgaagagaaaacagcagaagattat
tctgtggatgaaaatggacaaaggtggttttgcactggtgatattggagaattccatccc
gatggatgtttacagattatagatcgtaagaaagatctagtgaagttacaagcaggagag
tatgtatctcttgggaaagtagaagctgcactgaagaattgtccacttattgacaacatc
tgtgcttttgccaaaagtgatcagtcctatgtgatcagttttgtggttcctaaccagaaa
aggttgacacttttggcacaacagaaaggggtagaaggaacttgggttgatatctgcaat
aatcctgctatggaagctgaaatactgaaagaaattcgagaagctgcaaatgccatgaaa
ttggagcgatttgaaattccaatcaaggttcgattaagcccagagccatggacccctgaa
actggtttggtaactgatgctttcaaactgaaaaggaaggagctgaggaaccattacctc
aaagacattgaacgaatgtatgggggcaaataa

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