KEGG T01001: 221823

Homo sapiens (human): 221823

Entry

221823 CDS T01001

Gene name

PRPS1L1, PRPS1, PRPS3, PRPSL, PRS-III

Definition

phosphoribosyl pyrophosphate synthetase 1-like 1 (EC:2.7.6.1)

Orthology

K00948

ribose-phosphate pyrophosphokinase [EC:2.7.6.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa00030	Pentose phosphate pathway
hsa00230	Purine metabolism
hsa01100	Metabolic pathways
hsa01230	Biosynthesis of amino acids

Module

hsa_M00005

PRPP biosynthesis, ribose 5P => PRPP

Class

Metabolism; Carbohydrate metabolism; Pentose phosphate pathway [PATH:hsa00030]
Metabolism; Nucleotide metabolism; Purine metabolism [PATH:hsa00230]

SSDB

Motif

Pfam:

Pribosyltran_N Pribosyl_synth Pribosyltran UPRTase

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

7p21.1

AA seq 318 aa
MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGC
GEINDSLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRSPISAKLVANMLSIAG
ADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTS
IADQLNVDFALIHKERKKANEVDCIVLVGDVNDRVAILVDDMADTCVTICLAADKLLSAG
ATRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISMILAEAI
RRTHNGESVSYLFSHVPL

NT seq 957 nt +upstreamnt +downstreamnt
acgccgaatatcaaaatcttcagcggcagctcccaccaggacttatcccagaaaattgct
gaccgcctgggcctggagctaggcaaggtggtgactaagaaattcagcaaccaggagacc
tgcgtggaaattgatgagagtgtgcgtggagaggatgtctacatcgttcagagtggttgt
ggcgaaatcaacgacagtctaatggagcttttgatcatgattaatgcctgcaagattgct
tcagctagccgagttactgcagtcatcccatgcttcccttatgcccgacaggataagaag
gataagagccggtccccaatctctgccaagcttgttgcaaatatgctctctatagcaggt
gcggatcatatcatcaccatggacctacatgcttctcaaattcagggcttttttgatatc
ccagtagacaacttgtatgcagagccaactgtcctgaagtggataagggagaatatccct
gagtggaagaactgcattattgtctcgccagatgctggtggagctaaaagagtgacctcc
attgcagaccagttgaatgtggactttgctttgattcataaagaacggaagaaggccaat
gaagtggactgcatagtgctagtgggagatgtgaatgatcgtgtggctatccttgtagat
gacatggcagacacttgtgttacaatctgcctcgcagctgacaaacttctctcagctgga
gcaaccagagtttatgctatcttgactcatggaatcttttctggcccagccatttctcgc
atcaacactgcatgctttgaagcagtggtagtcaccaataccatacctcaagatgagaag
atgaagcattgctccaaaatacgagtaattgacatctccatgatccttgcagaagccata
aggagaactcataatggggaatctgtttcctacctgttcagccatgttcctttataa

All links

Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (4)   
   Pfam (4)   
All databases (37)   

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