KEGG T01001: 22953

Homo sapiens (human): 22953

Entry

22953 CDS T01001

Gene name

P2RX2, P2X2

Definition

purinergic receptor P2X, ligand-gated ion channel, 2

Orthology

K05216

P2X purinoceptor 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04020	Calcium signaling pathway
hsa04080	Neuroactive ligand-receptor interaction

Drug target

Suramin sodium:

D00808

Class

Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:hsa04020]
Environmental Information Processing; Signaling molecules and interaction; Neuroactive ligand-receptor interaction [PATH:hsa04080]

SSDB

Motif

Pfam:

P2X_receptor

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

12q24.33

AA seq 399 aa
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRIHRAEKLPGERDGPRELHHHQGQ
GDHHVRAQSVGRGGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMA
PNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESF
TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGT
TTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKV
YSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPA
FPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL

NT seq 1200 nt +upstreamnt +downstreamnt
atggccgccgcccagcccaagtaccccgccggggcgaccgcccggcgcctggcccggggc
tgctggtccgccctctgggactacgagacgcccaaggtgatcgtggtacgtattcatcgt
gcagaaaagctaccaggagagcgagacgggccccgagagctccatcatcaccaaggtcaa
ggggatcaccacgtccgagcacaaagtgtgggacgtggaggagtacgtgaagccccccga
ggcctgaggactgggcgctgtgtgccctattaccaggggccctccaagacctgcgaggtg
ttcggctggtgcccggtggaagatggggcctctgtcagccaatttctgggtacgatggcc
ccaaatttcaccatcctcatcaagaacagcatccactaccccaaattccacttctccaag
ggcaacatcgccgaccgcacagacgggtacctgaagcgctgcacgttccacgaggcctcc
gacctctactgccccatcttcaagctgggctttatcgtggagaaggctggggagagcttc
acagagctcgcacacaagggtggtgtcatcggggtcattatcaactgggactgtgacctg
gacctgcctgcatcggagtgcaaccccaagtactccttccggaggcttgaccccaagcac
gtgcctgcctcgtcaggctacaacttcaggtttgccaaatactacaagatcaatggcacc
accacccgcacgctcatcaaggcctacgggatccgcattgacgtcattgtgcatggacag
gccgggaagttcagcctgattcccaccattattaatctggccacagctctgacttccgtc
ggggtgggctccttcctgtgcgactggatcttgctaacattcatgaacaaaaacaaggtc
tacagccataagaaatttgacaaggtgtgtacgccgagccacccctcaggtagctggcct
gtgacccttgcccgtgtattgggccaggcccctcccgaacccggccaccgctccgaggac
cagcaccccagccctccatcaggccaggagggccaacaaggggcagagtgtggcccagcc
ttcccgcccctgcggccttgccccatctctgccccttctgagcagatggtggacactcct
gcctccgagcctgcccaagcctccacacccacagaccccaaaggtttggctcaactctga

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (13)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (30)   
   RefSeq(nuc) (6)   
   GenBank (12)   
   EMBL (12)   
Protein domain (1)   
   Pfam (1)   
All databases (66)   

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