KEGG   Homo sapiens (human): 23067Help
Entry
23067             CDS       T01001                                 

Gene name
SETD1B, KMT2G, Set1B
Definition
(RefSeq) SET domain containing 1B
  KO
K11422  
histone-lysine N-methyltransferase SETD1 [EC:2.1.1.43]
Organism
hsa  Homo sapiens (human)
Pathway
Lysine degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    23067 (SETD1B)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     23067 (SETD1B)
Chromosome [BR:hsa03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     23067 (SETD1B)
   HMT complexes
    COMPASS/SET1 complex
     23067 (SETD1B)
    COMPASS/SET1 complex (yeast)
     23067 (SETD1B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q9UPS6(Tbio)
Position
12q24.31
AA seq 1966 aa AA seqDB search
MENSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAMS
SNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLR
DMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDT
KGETRMRFYELLVTGRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSAGCGSGS
SSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLF
SQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGT
GGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAF
GARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSP
GTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQL
SPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGP
PDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM
VVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAH
PAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQ
VLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKF
DPSVPPPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKK
ERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLP
SFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVR
RRPARPLELDSGGEEDEKESLSASSSSSASSSSGSSTTSPSSSASDKEEEQESTEEEEEA
EEEEEEEVPRSQLSSSSTSSTSDKDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEE
ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEES
MASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVE
EPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP
LQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVP
ATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPS
GPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPL
PPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPV
FPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP
GPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTI
LYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAKKKKRDDGIR
EHVTGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSIPAQPHASTRAGSERRSE
QRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQN
IRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVE
SQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN
NT seq 5901 nt NT seq  +upstreamnt  +downstreamnt
atggagaacagtcaccccccccaccaccaccaccagcagcccccgccgcagcccggccct
tcgggcgagaggaggaaccaccattggagaagttacaagttgatgattgacccggctctg
aaaaaggggcatcataaactgtaccgctacgatgggcagcatttcagcctggcgatgtcc
agcaaccgcccggtggaaattgtcgaagatccccgggtcgtcgggatctggaccaaaaac
aaggagctggagctgtcggtgcccaaattcaagatcgatgagttctacgtgggcccggtg
cctccgaagcaggtgacatttgccaagctgaatgataacatccgtgaaaacttcctgagg
gacatgtgcaagaagtatggggaggtggaggaggtggagattttgtacaaccccaagacc
aagaagcacctgggcatcgccaaggtggtctttgccacggtccggggagccaaggatgcc
gttcagcacttgcacagcacttccgtcatgggcaacattatccacgtggagctggacacc
aaaggggaaacccgaatgcggttctatgaactgttggtcactggccgatacaccccccag
accctcccagtgggcgagctggacgctgtctctccaatcgtgaatgagaccctgcagctg
tcagatgccctgaagcgcctcaaggatggaggcctgtctgcaggctgtggctccggctcc
tcctctgtcacccccaatagcggtgggacacccttctcccaggacacagcttattccagc
tgccgcctggacacacccaactcctatggacagggcaccccgctcacaccgcgcctgggc
acccctttctcacaggactccagctactccagccgccagcccacaccctcatacctcttc
agccaggaccctgcagtgaccttcaaggcccggcgccacgagagcaagttcacggacgcc
tacaaccgccgccacgaacatcattatgtacacaattctcccgcggtcactgcggtggcc
ggggccacagccgctttccggggttcctcggacctcccgttcggagcagtcggcggcact
gggggcagcagcggtcccccgttcaaggctcaaccacaggattcagccacatttgcccac
actccaccacccgcccaagcaacccctgctcctggattcaagtctgctttctctccgtat
cagaccccagtggcccacttccctccacccccggaagagcccaccgccacagccgctttt
ggggcccgcgacagtggggagttccggagggcaccggcgcccccacccctgccacctgct
gagcctctggccaaggagaagccaggcacgccacccggcccgccgccccccgacaccaac
agcatggagctgggcggccggcccaccttcggctggagtcctgagccctgtgacagccct
ggcacgcccacgctggagtcgtcccctgcagggccagagaaaccccacgacagcctggac
tcgcgcatcgagatgctgctgaaggagcagcgcaccaagctgctcttcctgagggagccg
gactcggacaccgagctgcagatggagggcagccccatctcctcctcctcctcccagctc
tccccactggccccctttggcaccaactcccagccaggcttccggggccccacgcccccc
tcgtcacgcccctccagcaccggcctggaggatatcagcccaacacccctcccagactcc
gacgaggacgaggagctcgacctgggccttgggcctcggcctccacctgagccaggcccc
ccggaccctgctgggcttctgagccagacagctgaggtggccttggacctggttggagac
agaaccccgacctcagagaagatggatgagggccagcagtcctcaggcgaggacatggag
atctcggatgacgagatgccctcggcccccatcaccagcgctgactgccccaagcccatg
gtggtgaccccaggagcggcagccgtggcagccccttctgtgctagccccaaccctgccg
ctgcccccgccacctggcttccccccgctgccccccccaccaccaccacccccaccgcag
cctggcttccccatgcccccaccgctgcccccaccgccgcccccaccccctccagcccac
cctgctgtgacagtgcccccaccacccttgccagcgccgcctggagtcccgcccccaccc
atcctgccaccactgcccccctttccgccgggcctgttccctgtgatgcaggtggacatg
agccacgtgctgggtggccagtggggcggcatgcccatgtccttccagatgcaaacgcag
gtgctcagccggctgatgacgggccagggcgcctgcccctacccgcccttcatggccgct
gcggccgccgctgcctcagctgggctccagtttgtcaacctgccgccctaccggggcccc
ttctccctgagcaactccggcccaggccgcgggcagcactggccaccactgcccaagttt
gacccgtcagtgcctccaccaggctacatgccacgccaggaggacccacacaaagccacg
gtggatggcgtcctgctggtggtcctcaaagaactcaaggccatcatgaagcgtgacctg
aaccgcaagatggtggaagtggtggctttccgggcctttgacgagtggtgggacaagaag
gagcggatggccaaggcctcgctgaccccggtgaagtcgggcgagcacaaggacgaggac
aggccgaagcccaaggaccgcatcgcctcgtgcctgctggagtcatggggcaagggcgag
ggcctgggctacgagggcctgggcctgggcattgggctgcgtggggccattcgcctgccc
tccttcaaggtcaagaggaaggagccaccagacaccacctcatctggcgaccagaagcgg
ctgcggccctcgacctctgtggatgaggaagatgaagagtccgagcgagagcgagaccgg
gatatggcagacaccccctgtgagctcgccaagcgggaccccaagggcgtgggtgtgcgg
cggcggccggcgcggcctctggagctggacagtggtggggaggaggacgagaaggagtca
ttgtcggcgtcctcgtcctcatccgcgtcatcatcctcggggtcctcaaccacctcaccc
tcgtcctcggcctccgacaaggaggaggaacaggagagcaccgaggaggaagaggaggcg
gaggaggaggaggaggaggaagtccccaggagccagctctcctcctcctcaacctcatcc
acatcagataaggatgacgacgatgacgacagtgatgaccgggacgagtctgagaacgat
gacgaggacacagccctgtcagaggcgagtgagaaggacgaaggggactcggatgaagag
gagacagtgagcattgtaacctccaaggccgaagccacgtcgtccagtgagagttccgag
tcttctgagtttgagtcaagctccgagtcctcgccctcatcctcggaggatgaggaggag
gtagtggccagggaagaggaggaagaagaggaggaggaggagatggtggccgaggaaagc
atggcttctgcaggccctgaggactttgagcaggacggggaggaagcggctctggccccg
ggggcacctgcagtggactcgttgggcatggaagaggaggtggacatcgagactgaggct
gtggcccctgaggagcggccctccatgctggacgagccccccttgcctgtgggtgttgaa
gagccagcggactccagggagccgcctgaggaaccaggcctgagccaggaaggggccatg
ttgctgtctccagagccccctgccaaggaggtggaggctcgacccccattgtcccctgag
cgagctccagaacatgacctggaagtggagccggagccccctatgatgctccccttgccg
ctgcaaccaccattgccgcccccacgaccaccccggccacccagcccaccgccggagcct
gagaccacagatgcctcacacccatctgtccctccggagccccttgccgaggaccacccc
ccgcatactccaggcctctgtggcagcctggccaagtcgcagagcacagagacggtgcca
gccacaccaggcggggagcccccgctatcagggggcagcagtggcctgtccctgagctct
ccgcaagtgcccggcagccccttctcctacccagccccgtcccctagcttgagcagtggg
ggcctccctcggacacctggccgggacttcagcttcacacccaccttctccgagcccagc
gggcccttgctcctgcccgtctgcccactccccactggccgacgcgatgaacgctccggg
cccctggcctccccggtgctcctggagacgggcctgcccctccctctgccccttcccctg
cccttgcccttggcattgcccgccgtcttgcgggcccaggctcgtgcgcccaccccgctg
ccacccctgctgcccgcccccctggcctcttgccctcccccaatgaagaggaagccgggc
cggccccggcgatccccaccatctatgctctccttggatgggcccttggtccgaccacca
gcaggggccgcccttggaagggaactcctgctcctgccgggccagccacagacccccgtc
ttccccagcacccatgacccccggacggtgaccctggacttccggaacgcggggatccca
gcccctccaccaccccttcccccccagccacccccacccccacctcccccacctgtagag
cccaccaagctgccctttaaggagctagacaaccagtggccctccgaggccattcctccg
ggcccccgtgggcgcgatgaggtcactgaggaatacatggagttggccaagagccggggg
ccgtggcgccggccacctaagaagcgccatgaggacctggtgccacctgcgggctcgccc
gaactctcgccaccccagcccctcttccggccccgctcggagtttgaggagatgaccatc
ctgtatgacatctggaacggtggcatcgatgaggaggacatccgcttcctgtgtgtcacc
tacgagcgactgctacagcaggacaatggcatggactggcttaacgacacgctctgggtc
taccatccctccaccagcctctcttcagctaagaagaagaaacgggacgatggcatccgc
gagcacgtgacgggctgtgcccgcagtgagggcttctacaccatcgacaagaaggacaag
ctcagatacctcaacagcagccgtgccagcaccgatgagccccccgcagacacccagggc
atgagcatcccagcacagccccacgcctccacccgggcaggctcggagcggcgttcggag
cagcgccgcctgctgtcctccttcactggcagctgtgacagtgacctgctcaagttcaac
cagctcaagttccggaagaaaaagctcaagttctgcaagagccacattcacgactggggc
ttgttcgccatggagcccatcgcggctgacgagatggtcatcgagtacgtgggccagaat
atccgtcaggtgatcgcagacatgcgggagaagcgttatgaggacgagggcatcgggagc
agctacatgttccgggtggaccatgacaccatcatcgacgccaccaagtgcggcaacttc
gcgcgcttcatcaaccacagctgcaaccccaactgctatgccaaggtgatcacggtggag
tcacagaagaagatagtcatctactcgaagcagcacattaacgtcaatgaggagattacc
tatgactataagttccccatcgaggacgtcaagatcccctgcctctgtggctccgagaac
tgccgggggaccctcaactag

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