KEGG T01001: 23530

Homo sapiens (human): 23530

Entry

23530 CDS T01001

Gene name

NNT, GCCD4

Definition

nicotinamide nucleotide transhydrogenase (EC:1.6.1.2)

Orthology

K00323

NAD(P) transhydrogenase [EC:1.6.1.2]

Organism

hsa Homo sapiens (human)

Pathway

hsa00760	Nicotinate and nicotinamide metabolism
hsa01100	Metabolic pathways

Class

Metabolism; Metabolism of cofactors and vitamins; Nicotinate and nicotinamide metabolism [PATH:hsa00760]

SSDB

Motif

Pfam:

PNTB AlaDh_PNT_C AlaDh_PNT_N DUF3814 ComX Pyr_redox

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1DJL 1U31 1PT9

Position

5p12

AA seq 1086 aa
MANLLKTVVTGCSCPLLSNLGSCKGLRVKKDFLRTFYTHQELWCKAPVKPGIPYKQLTVG
VPKEIFQNEKRVALSPAGVQNLVKQGFNVVVESGAGEASKFSDDHYRVAGAQIQGAKEVL
ASDLVVKVRAPMVNPTLGVHEADLLKTSGTLISFIYPAQNPELLNKLSQRKTTVLAMDQV
PRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGL
ASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAE
MKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPG
ELYIHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFDVKDDFDFGTMG
HVIRGTVVMKDGKVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMSTASAYT
AGLTGILGLGIAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAV
GGLALMGGHLYPSTTSQGLAALAAFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLL
PAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLA
ATLGVLKPGPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIA
EYIIEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGLLKSAPLLLPGRHLL
NAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNS
YSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGG
KPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLTEQGKKVRF
GIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDP
NSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKV
RESYQK

NT seq 3261 nt +upstreamnt +downstreamnt
atggcaaacctattgaaaacagtggtgactggctgctcgtgtcctctacttagcaatttg
gggtcctgtaagggtctacgtgtgaagaaggattttttacgaacattttatactcaccaa
gaactgtggtgtaaagcgcctgtaaaaccaggaattccatataagcaactgactgttgga
gtccccaaagagatattccaaaatgagaagcgagtggcattgtctcctgctggtgttcag
aacttggtcaagcagggttttaatgttgtcgtggaatcgggtgcgggcgaagcttccaag
ttctcagatgatcactatagagtggcaggtgcccaaatccaaggggcaaaggaagtgctg
gcttctgatttggtggtcaaagtgcgagcccctatggttaatccaacattaggtgttcat
gaagctgaccttttaaagacatcaggaacgctgattagttttatttacccagcccaaaat
ccagagttgctaaataaactttcccaaagaaaaactacagttctggcaatggaccaggtt
ccaagagtcacaattgctcagggatatgatgcgctaagctccatggccaacattgcgggt
tataaggctgttgtcctagcagcaaatcattttggacgtttttttactggtcagatcaca
gctgctggaaaagttcctccagctaagattctgatagttggtggtggtgttgctgggctt
gcttctgcaggcgcagcaaagtcgatgggtgcaattgttcgaggatttgacacaagagct
gcagctttggaacagttcaagtctcttggtgctgagcccttggaggtggacttgaaggaa
tctggtgagggacaaggaggatatgcaaaagagatgtccaaagagttcattgaagctgaa
atgaaactctttgctcaacaatgcaaggaggtagacatccttatcagcacagcacttatt
ccaggtaaaaaagctccagttttatttaataaagaaatgattgagtcaatgaaggaaggt
tcagttgttgtggatttagctgctgaggctggtggaaactttgaaaccactaagccagga
gaactctacattcataagggaattactcacataggctacacagacctgcccagccgaatg
gccactcaggccagcaccctatattccaacaacatcaccaaactcctgaaggccatcagc
ccggacaaagataatttttattttgatgtgaaagatgactttgactttggtacgatgggt
catgtcattagaggaactgtagtgatgaaagatggtaaagtgattttcccagctcccaca
ccgaaaaatattcctcaaggtgccccagtaaaacagaagacagtggctgagctggaagct
gaaaaagcagctaccattacacccttcaggaagacaatgtcaacggcttctgcatataca
gcaggtctcacagggatactgggtttgggcattgcggctcccaatctagccttttctcag
atggtgaccacttttggcttggctggcattgtggggtatcataccgtctggggagtgacc
cctgctctccactcaccactgatgtctgtgacaaatgcaatctcagggctgactgcagtt
ggtgggttggcactgatgggaggacatttgtatccttccacaacttctcagggccttgct
gctcttgctgcattcatatcctctgtcaacattgcaggtggctttctggtgactcagaga
atgctggacatgttcaagcgtcccactgaccccccagaatacaactacctgtacctgctc
cctgccggcacctttgttggtggatatttagctgccctctacagtggttataacattgaa
cagatcatgtacctaggctcgggtttgtgctgtgtcggtgccttggctggcctctccacc
cagggaacagcacgtcttggcaatgcactgggcatgattggggttgctggaggactggca
gccaccctcggagtcctaaaaccgggcccagaattactagctcagatgtctggagcgatg
gctttgggtggtaccattggattgacaattgccaaacgcatccagatttctgatttacct
caattagttgctgcttttcacagtttagtgggtttggcagctgtacttacttgcatagct
gagtacattatagaatatccacattttgctacggatgcagcagcaaatctcaccaagatt
gtggcctacctcggcacttacattggtggcgtcacctttagtgggtctctcattgcctat
ggaaaattgcagggtctcctgaaatctgcccctctcctactgcctggaaggcacttactc
aatgcaggcttactggctgctagtgtgggcgggataatcccattcatggtggacccaagc
tttactactggcatcacctgtctgggttcagtgtctgctctctctgctgtcatgggtgtg
actttgacagctgctattgggggtgctgacatgcccgtcgttatcactgtgctgaacagc
tactcaggctgggccctgtgtgcagagggcttcctgctcaacaacaatctgctgaccatc
gtgggtgcactcataggctcgtctggtgctatcctgtcatacatcatgtgtgtggcaatg
aatcgctccctggctaatgtgattcttggaggctatggcaccacttcaacagctggtgga
aaacccatggaaatttctggcacacatacggaaatcaaccttgacaatgcaattgacatg
attcgagaagctaatagcattattattacaccaggctatggtctctgtgcagccaaagct
caataccccattgctgatttggtaaagatgctcactgagcaaggcaaaaaagtcaggttt
ggaattcacccagttgcaggccgaatgcctggtcagcttaatgtgctgctggctgaggct
ggtgtgccatatgacattgtgttggaaatggatgagatcaaccatgattttccagatact
gatttggtccttgtaattggagctaatgacactgttaattcagcagctcaagaagatccc
aactctattattgcaggcatgccagtccttgaggtctggaaatcaaagcaggtgattgtt
atgaagaggtctttgggtgttggctatgctgcagtggacaatccaatcttctacaaacct
aacacggccatgcttctaggtgatgccaagaaaacatgtgacgcgctccaggcgaaagtt
agagaatcctatcagaagtaa

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (2)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (11)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (30)   
   RefSeq(nuc) (2)   
   GenBank (14)   
   EMBL (14)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (72)   

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