KEGG   Homo sapiens (human): 23533Help
Entry
23533             CDS       T01001                                 

Gene name
PIK3R5, F730038I15Rik, FOAP-2, P101-PI3K, p101
Definition
phosphoinositide-3-kinase, regulatory subunit 5
Orthology
K02649  
phosphoinositide-3-kinase, regulatory subunit
Organism
hsa  Homo sapiens (human)
Pathway
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    23533 (PIK3R5)
   04015 Rap1 signaling pathway
    23533 (PIK3R5)
   04012 ErbB signaling pathway
    23533 (PIK3R5)
   04370 VEGF signaling pathway
    23533 (PIK3R5)
   04630 Jak-STAT signaling pathway
    23533 (PIK3R5)
   04668 TNF signaling pathway
    23533 (PIK3R5)
   04066 HIF-1 signaling pathway
    23533 (PIK3R5)
   04068 FoxO signaling pathway
    23533 (PIK3R5)
   04070 Phosphatidylinositol signaling system
    23533 (PIK3R5)
   04024 cAMP signaling pathway
    23533 (PIK3R5)
   04022 cGMP - PKG signaling pathway
    23533 (PIK3R5)
   04151 PI3K-Akt signaling pathway
    23533 (PIK3R5)
   04152 AMPK signaling pathway
    23533 (PIK3R5)
   04150 mTOR signaling pathway
    23533 (PIK3R5)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    23533 (PIK3R5)
  Cell growth and death
   04210 Apoptosis
    23533 (PIK3R5)
  Cellular commiunity
   04510 Focal adhesion
    23533 (PIK3R5)
 Organismal Systems
  Immune system
   04611 Platelet activation
    23533 (PIK3R5)
   04620 Toll-like receptor signaling pathway
    23533 (PIK3R5)
   04650 Natural killer cell mediated cytotoxicity
    23533 (PIK3R5)
   04660 T cell receptor signaling pathway
    23533 (PIK3R5)
   04662 B cell receptor signaling pathway
    23533 (PIK3R5)
   04664 Fc epsilon RI signaling pathway
    23533 (PIK3R5)
   04666 Fc gamma R-mediated phagocytosis
    23533 (PIK3R5)
   04670 Leukocyte transendothelial migration
    23533 (PIK3R5)
   04062 Chemokine signaling pathway
    23533 (PIK3R5)
  Endocrine system
   04910 Insulin signaling pathway
    23533 (PIK3R5)
   04915 Estrogen signaling pathway
    23533 (PIK3R5)
   04914 Progesterone-mediated oocyte maturation
    23533 (PIK3R5)
   04917 Prolactin signaling pathway
    23533 (PIK3R5)
   04921 Oxytocin signaling pathway
    23533 (PIK3R5)
   04919 Thyroid hormone signaling pathway
    23533 (PIK3R5)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    23533 (PIK3R5)
  Digestive system
   04973 Carbohydrate digestion and absorption
    23533 (PIK3R5)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    23533 (PIK3R5)
  Nervous system
   04725 Cholinergic synapse
    23533 (PIK3R5)
   04722 Neurotrophin signaling pathway
    23533 (PIK3R5)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    23533 (PIK3R5)
  Development
   04380 Osteoclast differentiation
    23533 (PIK3R5)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    23533 (PIK3R5)
   05205 Proteoglycans in cancer
    23533 (PIK3R5)
   05203 Viral carcinogenesis
    23533 (PIK3R5)
   05210 Colorectal cancer
    23533 (PIK3R5)
   05212 Pancreatic cancer
    23533 (PIK3R5)
   05214 Glioma
    23533 (PIK3R5)
   05221 Acute myeloid leukemia
    23533 (PIK3R5)
   05220 Chronic myeloid leukemia
    23533 (PIK3R5)
   05218 Melanoma
    23533 (PIK3R5)
   05211 Renal cell carcinoma
    23533 (PIK3R5)
   05215 Prostate cancer
    23533 (PIK3R5)
   05213 Endometrial cancer
    23533 (PIK3R5)
   05222 Small cell lung cancer
    23533 (PIK3R5)
   05223 Non-small cell lung cancer
    23533 (PIK3R5)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    23533 (PIK3R5)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    23533 (PIK3R5)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    23533 (PIK3R5)
   05166 HTLV-I infection
    23533 (PIK3R5)
   05162 Measles
    23533 (PIK3R5)
   05164 Influenza A
    23533 (PIK3R5)
   05161 Hepatitis B
    23533 (PIK3R5)
   05160 Hepatitis C
    23533 (PIK3R5)
   05169 Epstein-Barr virus infection
    23533 (PIK3R5)
   05146 Amoebiasis
    23533 (PIK3R5)
   05145 Toxoplasmosis
    23533 (PIK3R5)
   05142 Chagas disease (American trypanosomiasis)
    23533 (PIK3R5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
17p13.1
AA seq 880 aa AA seqDB search
MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLE
QILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYC
SICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVAN
KLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELA
SGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDI
LQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLS
LASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQK
FIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLP
QPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRR
LENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPW
EESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLL
YYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDG
DREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEV
VKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYK
PEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP
NT seq 2643 nt NT seq  +upstreamnt  +downstreamnt
atgcagccaggggccacgacatgcacggaggaccgcatccagcatgccctggaacgctgc
ctgcatggactcagcctcagccgccgctccacctcctggtcagctgggctgtgtctgaac
tgctggagcctgcaggagctggtcagcagggacccgggccacttccttatcctccttgag
cagatcctgcagaagacccgagaggtccaggagaagggcacctacgacctgctcaccccg
ctggccctgctcttctattccactgttctttgtacaccacacttcccaccagactcggat
ctccttctgaaggcagccagcacctaccaccggttcctgacctggcctgttccttactgc
agcatctgccaggagctgctcaccttcattgatgctgaactcaaggccccagggatctcc
taccagagactggtgagggctgagcagggcctgcccatcaggagtcaccgcagctccacc
gtcaccgtgctgctgctgaacccagtggaagtgcaggccgagttccttgctgtagccaat
aagctgagtacgcccggacactcgcctcacagtgcctacaccaccctgctcctgcacgcc
ttccaggccacctttggggcccactgtgacgtcccgggcctgcactgcaggctacaggcc
aagaccctggcagagcttgaggacatcttcacggagaccgcagaggcacaggagctggca
tctggcatcggggatgctgcagaggcccggcggtggctcaggaccaagctgcaggcggtg
ggagaaaaagctggcttccctggggtgttagacactgcaaaaccagggaagctccacacc
atccccatccctgtcgccaggtgctacacctacagctggagccaggacagctttgacatc
ctgcaggaaatcctgctcaaggaacaggagctactccagccagggatcctgggagatgat
gaagaggaggaagaggaggaggaggaggtggaggaggacttggaaactgacgggcactgt
gccgagagagattccctgctctccaccagctctttggcgtcccatgactccaccttgtcc
cttgcatcctcccaggcctcggggccggccctctcgcgccatctgctgacttcctttgtc
tcaggcctctctgatggcatggacagcggctacgtggaggacagcgaggagagctcctcc
gagtggccttggaggcgtggcagccaggaacgccgaggccaccgcaggcctgggcagaag
ttcatcaggatctataaactcttcaagagcaccagccagctggtactgcggagggactct
cggagcctggagggcagctcggacacggccctgcccctgaggcgggcagggagcctctgc
agccccctggacgaaccagtatcacccccttcccgggcccagcgctcccgctccctgccc
cagcccaaactcggtacccagctgcccagctggcttctggcccctgcttcacgcccccag
cgccgccgccccttcctgagtggagatgaggatcccaaggcttccacgctacgtgttgtg
gtctttggctccgatcggatttcagggaaggtggctcgggcgtacagcaaccttcggcgg
ctggagaacaatcgcccactcctcacacggttcttcaaacttcagttcttctacgtgcct
gtgaagcgaagtcatgggaccagccctggtgcctgtccaccccctcggagccagacgccc
tcacccccgacagactcccctaggcacgccagccctggagagctgggcaccaccccatgg
gaggagagcaccaatgacatctcccactacctcggcatgctggacccctggtatgagcgc
aatgtactgggcctcatgcacctgccccctgaagtcctgtgccagcagtccctgaaggct
gaagcccaggccctggagggctccccaacccagctgcccatcctggctgacatgctactc
tactactgccgctttgccgccagaccggtgctgctgcaagtctatcagaccgagctgacc
ttcatcactggggagaagacgacagagatcttcatccactccttggagctgggtcactcc
gctgccacacgtgccatcaaggcgtcaggtcctggcagcaagcggctgggcatcgatggc
gaccgggaggctgttcctctaacactacagattatttacagcaagggggccatcagtgga
cgaagtcgctggagcaacctggagaaggtctgtacctccgtgaacctcaacaaggcctgc
cggaagcaggaggagctggattccagcatggaggccctgacgctaaacctgacagaagtg
gtgaaaaggcagaactccaaatccaagaagggctttaaccagattagcacatcgcagatc
aaagtggacaaggtgcagatcatcggctccaacagctgcccctttgctgtgtgcctggac
caggatgagagaaagatcctgcagagtgtagtcagatgtgaggtctcaccgtgctacaag
ccagagaagagcgacctctcctcaccaccccagacgcctcctgacctgccggcccaggcc
gcacctgatctctgctcccttctctgcctgcccatcatgactttcagtggagctctgccc
tag

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