KEGG   Homo sapiens (human): 242Help
Entry
242               CDS       T01001                                 

Gene name
ALOX12B, 12R-LOX, ARCI2
Definition
arachidonate 12-lipoxygenase, 12R type (EC:1.13.11.-)
Orthology
K08021  
arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-]
Organism
hsa  Homo sapiens (human)
Pathway
Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Disease
H00734  
Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Lipid metabolism
   00590 Arachidonic acid metabolism
    242 (ALOX12B)
 Organismal Systems
  Nervous system
   04726 Serotonergic synapse
    242 (ALOX12B)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.-  
     242 (ALOX12B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
17p13.1
AA seq 701 aa AA seqDB search
MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD
LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGKT
TADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNGY
IPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIR
KIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLGE
GTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIAIQLSQ
TPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNLPMC
HPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYDSLY
LPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQSWVQEI
FKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPNFPASMR
NPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFVEEAPRR
SIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI
NT seq 2106 nt NT seq  +upstreamnt  +downstreamnt
atggccacctacaaagtcagggtggccacaggcaccgacctcttgtcgggaacacgggac
tccatctcactgaccattgtggggacacaaggagagagccataagcagctgctgaaccac
tttgggagagactttgcaactggggcggtgggccagtacaccgtgcagtgccctcaggac
ctgggtgagctcatcatcatccgcctgcacaaagagcggtacgccttcttccccaaggac
ccttggtactgcaactatgtgcagatctgtgcccccaacggccgtatctaccacttcccc
gcctaccagtggatggatggctacgagaccctggcactccgggaggccacaggaaagaca
acagcagatgactcgctccccgtcctcctggagcacagaaaagaggagatcagagccaag
caggacttctaccactggcgagtctttcttcctggcctgcccagctatgtgcacattccc
agttaccgccctccggtgcggaggcatcgcaaccccaaccggcctgagtggaatggctat
attccgggattcccaattctcatcaactttaaggccaccaagttcctgaacttaaatctc
cgctactccttcctcaagacggcctccttcttcgtccgcctggggcccatggcactggct
ttcaaagtccgcggcctgttggactgcaaacattcgtggaagaggctgaaggacattagg
aaaattttccctggcaagaaatctgtcgtctccgagtacgtggccgagcactgggcagag
gacaccttctttgggtaccagtacctcaacggcgtcaaccccggcctgatccgccgctgc
acgcggatcccagacaagttccccgtcacagacgacatggtggctccgttcctgggcgag
ggaacgtgcttgcaagcggagctggagaaggggaacatttacctggccgactaccgcatc
atggagggcatccccaccgtggagctcagcggccggaagcagcaccactgcgcccccctc
tgcctgctgcactttggacccgagggcaagatgatgcccatcgccatccagctcagccag
acccctgggccagattgccccatcttcctgcccagtgattctgagtgggactggctgcta
gccaagacgtgggtacgctatgcggagttctacagccacgaggccatcgcccacctgctg
gagacacacctcattgctgaggccttctgcctggccttgctgaggaacctgcccatgtgc
caccccctctacaagctcctcatcccccatacccgatacaccgtccagatcaacagcatt
ggccgggccgttctcctcaatgagggggggctctctgccaagggcatgtccctgggcgtg
gaaggctttgctggggtgatggtacgggctctgtcggagctcacctatgacagcctctac
ctccccaatgactttgtggagcgtggggtccaggacctgcctggatattactaccgcgat
gacagcttggcggtgtggaatgcactggagaagtatgtgacggagatcatcacctattat
tacccgagtgacgcagccgtggagggtgatccggaattgcagtcttgggtgcaggaaata
tttaaagagtgcctcctggggcgggagagctcaggcttccctaggtgcttgcgaaccgtg
cctgagctgatccgatatgtcactatagtcatctacacctgctctgccaagcacgctgct
gtcaacacaggccagatggagttcaccgcctggatgcccaacttcccagcgtccatgcgg
aatccaccgattcagactaaggggctgaccactctggagaccttcatggacacgttgccg
gatgtgaagaccacgtgcatcacgctgctggtgctctggaccctcagccgagagcctgac
gacaggcggcccctgggacacttcccggacattcacttcgtggaggaggccccgcggagg
agcatagaggcgttccgccagcgcctgaaccagatctcacacgacatccgccagcgcaac
aagtgccttcccatcccctactactacctggacccggtgctgattgagaacagcatttct
atttag

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