KEGG   Homo sapiens (human): 252969Help
Entry
252969            CDS       T01001                                 

Gene name
NEIL2, NEH2, NEI2
Definition
(RefSeq) nei like DNA glycosylase 2
  KO
K10568  endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03410  Base excision repair
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Genetic Information Processing
  Replication and repair
   03410 Base excision repair
    252969 (NEIL2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.2  Hydrolysing N-glycosyl compounds
    3.2.2.-  
     252969 (NEIL2)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.18  DNA-(apurinic or apyrimidinic site) lyase
     252969 (NEIL2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA glycosylases
     252969 (NEIL2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: H2TH zf-FPG_IleRS Fapy_DNA_glyco
Motif
Other DBs
NCBI-GeneID: 252969
NCBI-ProteinID: NP_001129218
OMIM: 608933
HGNC: 18956
Ensembl: ENSG00000154328
Vega: OTTHUMG00000090753
Pharos: Q969S2(Tbio)
UniProt: Q969S2 A0A024R361
Position
8p23.1
AA seq 332 aa AA seqDB search
MPEGPLVRKFHHLVSPFVGQQVVKTGGSSKKLQPASLQSLWLQDTQVHGKKLFLRFDLDE
EMGPPGSSPTPEPPQKEVQKEGAADPKQVGEPSGQKTLDGSSRSAELVPQGEDDSEYLER
DAPAGDAGRWLRVSFGLFGSVWVNDFSRAKKANKRGDWRDPSPRLVLHFGGGGFLAFYNC
QLSWSSSPVVTPTCDILSEKFHRGQALEALGQAQPVCYTLLDQRYFSGLGNIIKNEALYR
AGIHPLSLGSVLSASRREVLVDHVVEFSTAWLQGKFQGRPQHTQVYQKEQCPAGHQVMKE
AFGPEDGLQRLTWWCPQCQPQLSEEPEQCQFS
NT seq 999 nt NT seq  +upstreamnt  +downstreamnt
atgccagaagggccgttggtgaggaaatttcaccatttggtctccccctttgtgggtcag
caggtggtcaagacagggggcagcagtaagaagctacagcccgccagcctgcagtctctg
tggctccaggacacccaggtccatggaaagaaattattccttagatttgatctagatgaa
gaaatggggccccctggcagcagcccaacaccagagcctccacaaaaagaagtgcagaag
gaaggggctgcggacccaaagcaggtcggggagcccagcgggcagaagacccttgatgga
tcctcacggtctgcagagctcgtcccccagggcgaggatgattctgagtatttggagaga
gacgcccctgcaggagatgctgggaggtggctgcgtgtcagctttggtttgtttggcagc
gtttgggtgaacgatttctccagagccaagaaagccaacaagaggggggactggagggac
ccttccccgaggttggtcctgcactttggtggtggtggcttcctggcattttataattgt
cagttgtcttggagctcttccccagtggtcacacccacctgtgacatcctgtctgagaag
ttccatcgaggacaagccttagaagctctaggccaggctcagcctgtctgctatacactg
ctggaccagagatacttctcagggctagggaacatcattaagaatgaagccttgtacaga
gctgggatccatcccctttctctcggttcagtcctgagtgcctcgcgtcgggaggtcctg
gtggatcacgtggtggagttcagtacagcctggctgcagggcaagttccaaggcagaccg
cagcacacacaggtctaccagaaagaacagtgccctgctggccaccaggtcatgaaggag
gcgtttgggcccgaagatgggttacagaggctcacctggtggtgcccgcagtgccagccc
cagttgtcagaggagccagagcagtgccagttctcctaa

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