KEGG T01001: 2531

Homo sapiens (human): 2531

Entry

2531 CDS T01001

Gene name

KDSR, DHSR, FVT1, SDR35C1

Definition

3-ketodihydrosphingosine reductase (EC:1.1.1.102)

Orthology

K04708

3-dehydrosphinganine reductase [EC:1.1.1.102]

Organism

hsa Homo sapiens (human)

Pathway

hsa00600	Sphingolipid metabolism
hsa01100	Metabolic pathways

Module

hsa_M00094	Ceramide biosynthesis
hsa_M00099	Sphingosine biosynthesis

Class

Metabolism; Lipid metabolism; Sphingolipid metabolism [PATH:hsa00600]

SSDB

Motif

Pfam:

adh_short KR adh_short_C2 NAD_binding_10 Polysacc_synt_2 Epimerase THF_DHG_CYH_C ATP_bind_2 7kD_coat

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

18q21.3

AA seq 332 aa
MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
TTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLF
RTIALFYLGSFDSIVRRCMMQREKSENADKTA

NT seq 999 nt +upstreamnt +downstreamnt
atgctgctgctggctgccgccttcctcgtggccttcgtgctgctgctgtacatggtgtct
ccgctcatcagccccaagcccctcgccctgcccggggcgcatgtggtggttacaggaggt
tccagtggcatcgggaagtgcattgctatcgagtgctataaacaaggagcttttataact
ctggttgcacgaaatgaggataagctgctgcaggcaaagaaagaaattgaaatgcactct
attaatgacaaacaggtggtgctttgcatatcagttgatgtatctcaagactataaccaa
gtagagaatgtcataaaacaagcacaggagaaactgggtccagtggacatgctggtaaat
tgtgcaggaatggcagtgtcaggaaaatttgaagatcttgaagttagtacctttgaaagg
ttaatgagcatcaattacctgggcagcgtgtaccccagccgggccgtgatcaccaccatg
aaggagcgccgggtgggcaggatcgtgtttgtgtcctcccaggcaggacagttgggatta
ttcggtttcacagcctactctgcatccaagtttgccataaggggattggcagaagctttg
cagatggaggtgaagccatataatgtctacatcacagttgcttacccaccagacacagac
acacctggctttgccgaagaaaacagaacaaagcctttggagactcgacttatttcagag
accacatctgtgtgcaaaccagaacaggtggccaaacaaattgttaaagatgccatacaa
ggaaatttcaacagttcccttggctcagatgggtacatgctctcggccctgacctgtggg
atggctccagtaacttctattactgaggggctccagcaggtggtcaccatgggccttttc
cgcactattgctttgttttaccttggaagttttgacagcatagttcgtcgctgcatgatg
cagagagaaaaatctgaaaatgcagacaaaactgcctaa

All links

Pathway (4)   
   KEGG PATHWAY (2)   
   KEGG MODULE (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (9)   
   Pfam (9)   
All databases (59)   

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