KEGG T01001: 2550

Homo sapiens (human): 2550

Entry

2550 CDS T01001

Gene name

GABBR1, GABABR1, GABBR1-3, GB1, GPRC3A, dJ271M21.1.1, dJ271M21.1.2

Definition

gamma-aminobutyric acid (GABA) B receptor, 1

Orthology

K04615

gamma-aminobutyric acid type B receptor

Organism

hsa Homo sapiens (human)

Pathway

hsa04080	Neuroactive ligand-receptor interaction
hsa04727	GABAergic synapse
hsa04915	Estrogen signaling pathway
hsa05032	Morphine addiction

Drug target

Baclofen:

D00241

Aminobutyric acid:

D00058

Other:

D08861 D09791

Class

Environmental Information Processing; Signaling molecules and interaction; Neuroactive ligand-receptor interaction [PATH:hsa04080]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:hsa04915]
Organismal Systems; Nervous system; GABAergic synapse [PATH:hsa04727]
Human Diseases; Substance dependence; Morphine addiction [PATH:hsa05032]

SSDB

Motif

Pfam:

ANF_receptor 7tm_3 Peripla_BP_6 Sushi Bap31 DUF2975 Orbi_VP5 IncA

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

6p21.31

AA seq 961 aa
MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD
YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP
ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG
GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI
ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL
FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR
IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE
GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA
LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE
QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS
LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP
FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM
DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL
LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA
IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK
IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY
K

NT seq 2886 nt +upstreamnt +downstreamnt
atgttgctgctgctgctactggcgccactcttcctccgccccccgggcgcgggcggggcg
cagacccccaacgccacctcagaaggttgccagatcatacacccgccctgggaagggggc
atcaggtaccggggcctgactcgggaccaggtgaaggctatcaacttcctgccagtggac
tatgagattgagtatgtgtgccggggggagcgcgaggtggtggggcccaaggtccgcaag
tgcctggccaacggctcctggacagatatggacacacccagccgctgtgtccgaatctgc
tccaagtcttatttgaccctggaaaatgggaaggttttcctgacgggtggggacctccca
gctctggacggagcccgggtggatttccggtgtgaccccgacttccatctggtgggcagc
tcccggagcatctgtagtcagggccagtggagcacccccaagccccactgccaggtgaat
cgaacgccacactcagaacggcgcgcagtgtacatcggggcactgtttcccatgagcggg
ggctggccagggggccaggcctgccagcccgcggtggagatggcgctggaggacgtgaat
agccgcagggacatcctgccggactatgagctcaagctcatccaccacgacagcaagtgt
gatccaggccaagccaccaagtacctatatgagctgctctacaacgaccctatcaagatc
atccttatgcctggctgcagctctgtctccacgctggtggctgaggctgctaggatgtgg
aacctcattgtgctttcctatggctccagctcaccagccctgtcaaaccggcagcgtttc
cccactttcttccgaacgcacccatcagccacactccacaaccctacccgcgtgaaactc
tttgaaaagtggggctggaagaagattgctaccatccagcagaccactgaggtcttcact
tcgactctggacgacctggaggaacgagtgaaggaggctggaattgagattactttccgc
cagagtttcttctcagatccagctgtgcccgtcaaaaacctgaagcgccaggatgcccga
atcatcgtgggacttttctatgagactgaagcccggaaagttttttgtgaggtgtacaag
gagcgtctctttgggaagaagtacgtctggttcctcattgggtggtatgctgacaattgg
ttcaagatctacgacccttctatcaactgcacagtggatgagatgactgaggcggtggag
ggccacatcacaactgagattgtcatgctgaatcctgccaatacccgcagcatttccaac
atgacatcccaggaatttgtggagaaactaaccaagcgactgaaaagacaccctgaggag
acaggaggcttccaggaggcaccgctggcctatgatgccatctgggccttggcactggcc
ctgaacaagacatctggaggaggcggccgttctggtgtgcgcctggaggacttcaactac
aacaaccagaccattaccgaccaaatctaccgggcaatgaactcttcgtcctttgagggt
gtctctggccatgtggtgtttgatgccagcggctctcggatggcatggacgcttatcgag
cagcttcagggtggcagctacaagaagattggctactatgacagcaccaaggatgatctt
tcctggtccaaaacagataaatggattggagggtcccccccagctgaccagaccctggtc
atcaagacattccgcttcctgtcacagaaactctttatctccgtctcagttctctccagc
ctgggcattgtcctagctgttgtctgtctgtcctttaacatctacaactcacatgtccgt
tatatccagaactcacagcccaacctgaacaacctgactgctgtgggctgctcactggct
ttagctgctgtcttccccctggggctcgatggttaccacattgggaggaaccagtttcct
ttcgtctgccaggcccgcctctggctcctgggcctgggctttagtctgggctacggttcc
atgttcaccaagatttggtgggtccacacggtcttcacaaagaaggaagaaaagaaggag
tggaggaagactctggaaccctggaagctgtatgccacagtgggcctgctggtgggcatg
gatgtcctcactctcgccatctggcagatcgtggaccctctgcaccggaccattgagaca
tttgccaaggaggaacctaaggaagatattgacgtctctattctgccccagctggagcat
tgcagctccaggaagatgaatacatggcttggcattttctatggttacaaggggctgctg
ctgctgctgggaatcttccttgcttatgagaccaagagtgtgtccactgagaagatcaat
gatcaccgggctgtgggcatggctatctacaatgtggcagtcctgtgcctcatcactgct
cctgtcaccatgattctgtccagccagcaggatgcagcctttgcctttgcctctcttgcc
atagttttctcctcctatatcactcttgttgtgctctttgtgcccaagatgcgcaggctg
atcacccgaggggaatggcagtcggaggcgcaggacaccatgaagacagggtcatcgacc
aacaacaacgaggaggagaagtcccggctgttggagaaggagaaccgtgaactggaaaag
atcattgctgagaaagaggagcgtgtctctgaactgcgccatcaactccagtctcggcag
cagctccgctcccggcgccacccaccgacacccccagaaccctctgggggcctgcccagg
ggaccccctgagccccccgaccggcttagctgtgatgggagtcgagtgcatttgctttat
aagtga

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Drug (4)   
   KEGG DRUG (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (16)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (3)   
   RefSeq(pep) (3)   
DNA sequence (42)   
   RefSeq(nuc) (4)   
   GenBank (19)   
   EMBL (19)   
Protein domain (8)   
   Pfam (8)   
All databases (94)   

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