KEGG   Homo sapiens (human): 2560Help
Entry
2560              CDS       T01001                                 

Gene name
GABRB1
Definition
gamma-aminobutyric acid (GABA) A receptor, beta 1
Orthology
K05181  
gamma-aminobutyric acid receptor subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
Serotonergic synapse
GABAergic synapse
Morphine addiction
Nicotine addiction
Drug target
Hexobarbital: 
Thiopental: 
Propofol: 
Methylphenobarbital: 
Phenobarbital: 
Clonazepam: 
Aminobutyric acid: 
Diazepam: 
Chlordiazepoxide: 
Medazepam: 
Oxazepam: 
Potassium clorazepate: 
Lorazepam: 
Adinazolam: 
Bromazepam: 
Clobazam: 
Prazepam: 
Alprazolam: 
Nordazepam: 
Fludiazepam: 
Ethyl loflazepate: 
Etizolam: 
Clotiazepam: 
Cloxazolam: 
Tofisopam: 
Meprobamate: 
Pentobarbital: 
Amobarbital: 
Barbital: 
Secobarbital: 
Flurazepam: 
Nitrazepam: 
Flunitrazepam: 
Estazolam: 
Triazolam: 
Lormetazepam: 
Temazepam: 
Midazolam: 
Brotizolam: 
Quazepam: 
Loprazolam: 
Glutethimide: 
Zopiclone: 
Zolpidem: 
Eszopiclone: 
Methaqualone: 
Pentetrazol: 
Flumazenil: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    2560 (GABRB1)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    2560 (GABRB1)
   04726 Serotonergic synapse
    2560 (GABRB1)
   04723 Retrograde endocannabinoid signaling
    2560 (GABRB1)
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    2560 (GABRB1)
   05033 Nicotine addiction
    2560 (GABRB1)
Ion channels [BR:hsa04040]
 Cys-loop superfamily
  GABA-A
   2560 (GABRB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
4p12
AA seq 474 aa AA seqDB search
MWTVQNRESLGLLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPP
VDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPD
TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
SYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLK
RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKI
PYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQ
VDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDR
HGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH
NT seq 1425 nt NT seq  +upstreamnt  +downstreamnt
atgtggacagtacaaaatcgagagagtctggggcttctctctttccctgtgatgattacc
atggtctgttgtgcacacagcaccaatgaacccagcaacatgtcatacgtgaaagagaca
gtggacagattgctcaaaggatatgacattcgcttgcggccggacttcggagggcccccc
gtcgacgttgggatgcggatcgatgtcgccagcatagacatggtctccgaagtgaatatg
gattatacactcaccatgtatttccagcagtcttggaaagacaaaaggctttcttattct
ggaatcccactgaacctcaccctagacaatagggtagctgaccaactctgggtaccagac
acctactttctgaatgacaagaaatcatttgtgcatggggtcacagtgaaaaatcgaatg
attcgactgcatcctgatggaacagttctctatggactccgaatcacaaccacagctgca
tgtatgatggatcttcgaagatatccactggatgagcagaactgcaccctggagatcgaa
agttatggctataccactgatgacattgaattttactggaatggaggagaaggggcagtc
actggtgttaataaaatcgaacttcctcaattttcaattgttgactacaagatggtgtct
aagaaggtggagttcacaacaggagcgtatccacgactgtcactaagttttcgtctaaag
agaaacattggttacttcattttgcaaacctacatgccttctacactgattacaattctg
tcctgggtgtctttttggatcaactatgatgcatctgcagccagagtcgcactaggaatc
acgacagtgcttacaatgacaaccatcagcacccacctcagggagaccctgccaaagatc
ccttatgtcaaagcgattgatatttatctgatgggttgctttgtgtttgtgttcctggct
ctgctggagtatgcctttgtaaattacatcttctttgggaaaggccctcagaaaaaggga
gctagcaaacaagaccagagtgccaatgagaagaataaactggagatgaataaagtccag
gtcgacgcccacggtaacattctcctcagcaccctggaaatccggaatgagacgagtggc
tcggaagtgctcacgagcgtgagcgaccccaaggccaccatgtactcctatgacagcgcc
agcatccagtaccgcaagcccctgagcagccgcgaggcctacgggcgcgccctggaccgg
cacggggtacccagcaaggggcgcatccgcaggcgtgcctcccagctcaaagtcaagatc
cccgacttgactgatgtgaattccatagacaagtggtcccgaatgtttttccccatcacc
ttttctctttttaatgtcgtctattggctttactatgtacactga

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