KEGG   Homo sapiens (human): 2561Help
Entry
2561              CDS       T01001                                 

Gene name
GABRB2
Definition
(RefSeq) gamma-aminobutyric acid type A receptor beta2 subunit
  KO
K05181  
gamma-aminobutyric acid receptor subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
Serotonergic synapse
GABAergic synapse
Morphine addiction
Nicotine addiction
Drug target
Abecarnil: 
Adinazolam (DG00911): 
Adipiplon: 
Alprazolam: 
Aminobutyric acid: 
Amobarbital (DG00916): 
Barbital: 
Bretazenil: 
Bromazepam: 
Brotizolam: 
Chlordiazepoxide (DG00908): 
Clobazam: 
Clonazepam: 
Clotiazepam: 
Cloxazolam: 
Delorazepam: 
Dextofisopam: 
Diazepam: 
Estazolam: 
Eszopiclone: 
Ethyl loflazepate: 
Etizolam: 
Fludiazepam: 
Flumazenil: 
Flunitrazepam: 
Flurazepam (DG00919): 
Flutazolam: 
Flutoprazepam: 
Gaboxadol: 
Ganaxolone: 
Glutethimide: 
Haloxazolam: 
Hexobarbital: 
Indiplon: 
Iomazenil: 
Levotofisopam: 
Loprazolam (DG00921): 
Lorazepam: 
Lormetazepam: 
Medazepam (DG00909): 
Meprobamate: 
Methaqualone: 
Methylphenobarbital: 
Mexazolam: 
Midazolam (DG00920): 
Nimetazepam: 
Nitrazepam: 
Nordazepam: 
Ocinaplon: 
Oxazepam: 
Oxazolam: 
Pagoclone: 
Pentetrazol: 
Pentobarbital (DG00915): 
Phenobarbital (DG00845): 
Potassium clorazepate (DG01218): 
Prazepam: 
Propofol (DG00797): 
Quazepam: 
Remimazolam besilate: 
Rilmazafone (DG01307): 
Sarmazenil: 
Secobarbital (DG00917): 
Temazepam: 
Thiamylal (DG01377): 
Thiopental (DG00790): 
Tofisopam: 
Triazolam: 
Zolpidem (DG00922): 
Zopiclone: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    2561 (GABRB2)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    2561 (GABRB2)
   04726 Serotonergic synapse
    2561 (GABRB2)
   04723 Retrograde endocannabinoid signaling
    2561 (GABRB2)
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    2561 (GABRB2)
   05033 Nicotine addiction
    2561 (GABRB2)
Ion channels [BR:hsa04040]
 Cys-loop superfamily
  GABA-A
   2561 (GABRB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
5q34
AA seq 512 aa AA seqDB search
MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV
AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT
YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES
YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR
NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP
YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKI
FYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEA
VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD
LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
NT seq 1539 nt NT seq  +upstreamnt  +downstreamnt
atgtggagagtgcggaaaaggggctactttgggatttggtccttccccttaataatcgcc
gctgtctgtgcgcagagtgtcaatgaccctagtaatatgtcgctggttaaagagacggtg
gatagactcctgaaaggctatgacattcgtctgagaccagattttggaggtccccccgtg
gctgtggggatgaacattgacattgccagcatcgatatggtttctgaagtcaatatggat
tataccttgacaatgtactttcaacaagcctggagagataagaggctgtcctataatgta
atacctttaaacttgactctggacaacagagtggcagaccagctctgggtgcctgatacc
tatttcctgaacgataagaagtcatttgtgcacggagtgactgttaagaaccgcatgatt
cgcctgcatcctgatggcaccgtcctttatggactcagaatcacaaccacagctgcctgc
atgatggacctaaggaggtacccactggatgaacaaaactgcaccttggaaattgagagc
tatggatacacaactgatgacattgagttttactggcgtggcgatgataatgcagtaaca
ggagtaacgaaaattgaacttccacagttctctattgtagattacaaacttatcaccaag
aaggttgttttttccacaggttcctatcccaggttatccctcagctttaagcttaagaga
aacattggctactttatcctgcaaacatacatgccttccatcctgattaccatcctctcc
tgggtctccttctggattaattacgatgcttcagctgcaagggtggcattaggaatcaca
actgtcctcacaatgaccacaatcaacacccacctccgggaaactctccctaaaatcccc
tatgtgaaggccattgacatgtacctgatggggtgctttgtcttcgttttcatggccctt
ctggaatatgccctagtcaactacatcttctttgggagggggccccaacgccaaaagaaa
gcagctgagaaggctgccagtgccaacaatgagaagatgcgcctggatgtcaacaagatt
ttttataaagatattaaacaaaatgggacccaatatcgatccttgtgggaccctactgga
aacctctccccaactagacggactaccaattacgatttctctctgtatacgatggacccc
catgagaacatcttactgagcactctcgagataaaaaatgaaatggccacatctgaggct
gtgatgggacttggagaccccagaagcacaatgctagcctatgatgcctccagcatccag
tatcggaaagctgggttgcccaggcatagttttggccgaaatgctctggaacgacatgtg
gcgcaaaagaaaagtcgcctgaggagacgcgcctcccaactgaaaatcaccatccctgac
ttgactgatgtgaatgccatagatcggtggtcccgcatattcttcccagtggttttttcc
ttcttcaacatcgtctattggctttattatgtgaactaa

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