KEGG   Homo sapiens (human): 25759Help
Entry
25759             CDS       T01001                                 

Gene name
SHC2, SCK, SHCB, SLI
Definition
SHC (Src homology 2 domain containing) transforming protein 2
Orthology
K17447  
SHC- transforming protein 2
Organism
hsa  Homo sapiens (human)
Pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
VEGF signaling pathway
Focal adhesion
Natural killer cell mediated cytotoxicity
Neurotrophin signaling pathway
Insulin signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Bacterial invasion of epithelial cells
Glioma
Chronic myeloid leukemia
Class
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:hsa04014]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:hsa04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:hsa04370]
Cellular Processes; Cell communication; Focal adhesion [PATH:hsa04510]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:hsa04650]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:hsa04062]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:hsa04910]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:hsa04915]
Organismal Systems; Endocrine system; Prolactin signaling pathway [PATH:hsa04917]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:hsa04722]
Human Diseases; Cancers; Glioma [PATH:hsa05214]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:hsa05220]
Human Diseases; Substance dependence; Alcoholism [PATH:hsa05034]
Human Diseases; Infectious diseases; Bacterial invasion of epithelial cells [PATH:hsa05100]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
UniProt: 
Position
19p13.3
AA seq 582 aa AA seqDB search
MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPGGFLGRGPAAARAAGASGGA
DPQPEPAGPGGVPALAAAVLGACEPRCAAPCPLPALSRCRGAGSRGSRGGRGAAGSGDAA
AAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTR
EAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQ
VIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFEL
RFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALT
QPCALTALDQGPSPSLRDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGL
DAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEE
QLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGV
VRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSREP
NT seq 1749 nt NT seq  +upstreamnt  +downstreamnt
atgacgcagggtccgggcgggcgcgcgcccccggcgccccccgcgccccccgagcccgag
gcgcccaccaccttctgcgcgttgctgccccgaatgccgcagtggaagttcgcggccccg
ggcggcttcctgggccgcggcccggcggcggcgcgggcggctggggcctcggggggcgcg
gacccccaacccgagccggcgggcccggggggcgtcccggcgctggcggccgccgtcctg
ggcgcctgcgagccccgctgcgccgcgccctgtcccctgcccgcgctcagccgctgtcgg
ggcgcggggtcgcgggggtcgcggggcgggcggggggcggcggggtccggggacgccgcc
gccgccgccgagtggatccggaagggcagcttcatccacaaacccgcgcacggctggcta
caccccgacgccagggtcctggggcccggggtctcctacgtcgtgcggtacatgggctgc
atcgaggttctccgctctatgcgctccctggactttaacacgcgcacgcaggtgaccagg
gaagccatcaaccggctccatgaggccgtgcctggcgtccggggatcctggaagaaaaag
gcccccaacaaggccctggcgtccgtcctgggcaagagcaaccttcgctttgccggcatg
agcatctccatccacatctccactgatggcctcagcctctccgtgcctgccacgcgccag
gtcatcgccaaccaccacatgccgtccatctccttcgcgtcaggcggagacacggacatg
acggattacgtggcctacgtcgccaaggaccccatcaaccagagagcctgccacatcctg
gagtgctgtgagggcctggcacagagcatcatcagcaccgtgggccaagctttcgagctg
cgcttcaagcagtacctgcacagcccgcccaaggtggcgctgcccccagaaaggctggca
gggccggaggagtcggcctggggggacgaggaggactctttggagcacaattactacaac
agcatcccggggaaggagccgccgctgggcgggctagtggactccaggctggccctgaca
cagccctgcgccctcacggccctcgaccagggcccatctccttctctaagagatgcctgc
agcctgccatgggacgtggggtccaccggtacagctccaccgggggacggctacgtgcag
gcggacgcccggggccccccggaccacgaggagcacctgtatgtcaacacccagggtctg
gacgcccccgagccggaggacagccccaaaaaggatctgtttgacatgcgaccctttgag
gatgccctgaagttgcatgagtgctcagtggcggcaggcgtgacagcagcccctcttccc
ttggaggaccagtggcccagcccccctacccgccgggcccctgtggcccccacggaggaa
cagctgcgtcaggagccctggtaccacggccggatgagccgccgggcggcagagaggatg
cttcgagctgacggggacttccttgtgcgagacagcgtcaccaaccccgggcagtatgtc
ctcaccggcatgcacgccgggcagcccaagcacctgctgctcgtggaccccgagggcgtg
gtacggacgaaggacgtgctgtttgagagcatcagccacctgatcgaccaccacctgcag
aacgggcagcccatcgtggccgccgagagtgagctgcacctgcgtggcgtggtctcacgg
gagccctga

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