KEGG   Homo sapiens (human): 26061Help
Entry
26061             CDS       T01001                                 

Gene name
HACL1, 2-HPCL, HPCL, HPCL2, PHYH2
Definition
(RefSeq) 2-hydroxyacyl-CoA lyase 1
  KO
K12261  2-hydroxyacyl-CoA lyase 1 [EC:4.1.-.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04146  Peroxisome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Transport and catabolism
   04146 Peroxisome
    26061 (HACL1)
Enzymes [BR:hsa01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.-  Carbon-carbon lyases
    4.1.-.-  
     26061 (HACL1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: TPP_enzyme_N TPP_enzyme_M TPP_enzyme_C CO_dh PcrB
Motif
Other DBs
NCBI-GeneID: 26061
NCBI-ProteinID: NP_036392
OMIM: 604300
HGNC: 17856
Ensembl: ENSG00000131373
Vega: OTTHUMG00000129862
Pharos: Q9UJ83(Tbio)
UniProt: Q9UJ83
Position
3p25.1
AA seq 578 aa AA seqDB search
MPDSNFAERSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNE
QAACYAASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMG
AFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVNLQVN
VNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQY
KLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVK
FIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPESKWWKTLREKMKSN
EAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDA
GTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVV
NNNGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQK
SLRQSLADTTKPSLINIMIEPQATRKAQDFHWLTRSNM
NT seq 1737 nt NT seq  +upstreamnt  +downstreamnt
atgccggacagtaacttcgcagagcgcagcgaggagcaggtgtctggtgctaaagtcatc
gctcaggccctgaaaacgcaagatgtggagtacatatttggcatcgtaggcatcccagtg
accgaaatcgccattgctgcccagcagctaggcatcaagtacatcgggatgaggaatgag
caagcggcttgttatgctgcctccgcgattggatatctgacaagcaggccaggagtctgc
cttgttgtttctggcccaggtctcatccatgccttgggcggtatggcaaatgcaaacatg
aactgctggcccttgcttgtgattggtggttcctctgaaagaaaccaagaaacaatggga
gctttccaggagtttcctcaggttgaagcttgtagattatataccaagttctctgcccgc
ccaagcagcatagaagctattccttttgttattgaaaaggcagtgagaagcagtatctat
ggtcgtccaggtgcttgctatgttgacataccagcagattttgtgaaccttcaggtgaat
gtgaattctataaagtacatggaacgctgcatgtcacctcctattagcatggcagaaacc
tctgctgtgtgcacggcggcttctgttattaggaatgccaaacaaccccttcttatcatc
gggaaaggtgctgcttacgctcatgcagaagagagtatcaagaaattggtggagcaatat
aaactgccatttttgcccacccctatggggaagggtgttgtccctgacaaccatccatac
tgtgtaggtgcagccagatccagggctttgcaatttgctgatgtaattgtgttatttggt
gccagactaaattggattttacattttggactgcctccaagatatcagccagatgtgaag
tttatccaggttgatatctgtgcagaagaattggggaataatgtaaagcccgctgttact
ttgctaggaaacatacatgctgtcactaagcagcttttagaggaacttgataaaacacca
tggcagtatcctccagagagcaagtggtggaaaactctgagagaaaaaatgaagagcaat
gaagctgcatccaaggaactagcttctaaaaaatccctgcctatgaattattacacagta
ttctaccatgttcaagaacaactacctagagactgtttcgtggtaagtgaaggagcaaat
actatggacattggacggactgtgcttcagaactaccttcctcgtcacaggcttgatgct
ggtactttcggaacaatgggagttggtttgggatttgctattgcagctgccgtggtggct
aaagatagaagccctgggcaatggatcatctgtgtggaaggagacagtgcatttgggttt
tctggcatggaggtagaaaccatctgcaggtacaacttgccaatcatactgttggtagtg
aataacaatggaatttaccaaggttttgatacagatacttggaaagaaatgttaaaattt
caagatgctactgcagtggtccctccaatgtgtttgctgccaaattcacattatgagcaa
gtcatgactgcatttggaggcaaagggtattttgtacaaacaccagaagaactccaaaaa
tccctgaggcagagcctagcagacacaactaaaccttctcttatcaacatcatgattgag
ccacaagccacacggaaggcccaggattttcattggctgacccgctctaatatgtaa

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