KEGG   Homo sapiens (human): 26249
Entry
26249             CDS       T01001                                 
Symbol
KLHL3, PHA2D
Name
(RefSeq) kelch like family member 3
  KO
K10443  kelch-like protein 2/3
Organism
hsa  Homo sapiens (human)
Disease
H00243  Hyperkalemic distal renal tubular acidosis (RTA type 4)
H02310  Renal tubular acidosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    26249 (KLHL3)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul3 complex
    Adoptor and target recognizing subunit (BTB)
     26249 (KLHL3)
SSDB
Motif
Pfam: Kelch_1 Kelch_6 BACK Kelch_3 BTB Kelch_2 Kelch_4 KLHL33-like_BTB_POZ Skp1_POZ SANBR_BTB
Other DBs
NCBI-GeneID: 26249
NCBI-ProteinID: NP_059111
OMIM: 605775
HGNC: 6354
Ensembl: ENSG00000146021
UniProt: Q9UH77
Structure
Position
5:complement(137617500..137736089)
AA seq 587 aa
MEGESVKLSSQTLIQAGDDEKNQRTITVNPAHMGKAFKVMNELRSKQLLCDVMIVAEDVE
IEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENV
QVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFP
EVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVR
LPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLP
KVMIVVGGQAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLR
VRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNE
WFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRR
SGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLY
VVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL
NT seq 1764 nt   +upstreamnt  +downstreamnt
atggagggtgaaagtgtcaagctgagctcccagactctgatacaggctggggatgatgag
aagaaccagaggacgatcactgtcaaccctgcccacatggggaaagcattcaaggttatg
aatgaactgcggagtaaacagctgttgtgtgacgtgatgattgtggcagaagatgtcgag
atagaagcccaccgtgtggtcctggcagcctgcagcccctacttctgtgcgatgttcaca
ggtgacatgtctgagagtaaagccaaaaagatagaaatcaaggacgtggatgggcagacg
ctgagtaagctgattgactacatctatactgctgaaatcgaggtgactgaagagaatgtc
caggtgctgctcccggcagccagcttgctgcagctcatggatgttcggcagaactgctgt
gacttcctgcagtctcagttgcatcccaccaattgcctgggcatccgtgcatttgcagat
gtacacacctgcactgaccttctgcagcaggccaatgcctacgcagagcagcactttcca
gaggtgatgctaggagaagaatttcttagcctgagtctggaccaggtgtgcagcttgata
tccagcgacaagctgaccgtttcttcagaagagaaggtgtttgaagctgtgatctcatgg
atcaattatgagaaagaaacccgtttagagcacatggcaaagctgatggaacatgtccga
cttcctctcttacctagggactacctagtccaaacggttgaagaagaagctttgataaag
aataacaacacctgtaaagacttcctcattgaggccatgaaataccatctcctccctctg
gatcagagactattgattaagaacccaaggaccaagcccaggactccagtcagccttccc
aaggtcatgattgtggttggcggccaggcacccaaggcaatccgcagtgtggagtgctat
gatttcgaggaggaccggtgggatcagattgctgagcttccttccagaagatgcagagca
ggtgtggtgttcatggctggccacgtgtatgccgtgggagggtttaatggctcactgcgg
gtgcggacagtggatgtgtatgacggcgtgaaggaccagtggacgtccattgccagcatg
caggagcgccggagcacactgggcgcagcggtgctcaatgacttgctctacgcagtggga
ggctttgatggcagtactggcctagcatcggtggaagcctacagctacaagaccaacgag
tggttctttgtggccccgatgaacacgcggcggagcagtgtgggtgtgggcgttgtggag
gggaagctatatgctgttgggggttatgatggagcttcccgccagtgtctgagcactgtg
gagcagtacaacccagcgaccaatgaatggatatacgtggcggacatgagcacccgccgc
agtggcgcaggggttggagtgcttagcggacagctgtacgccacaggtgggcatgatggg
cctttggtgaggaagagcgttgaggtttacgatcctggaacaaatacctggaagcaagtg
gcagacatgaacatgtgccggcgcaacgcaggggtctgtgcagtaaatgggctcctgtat
gtggttggaggggatgatggatcctgcaacttggcttcggtggagtactacaatcctgtc
actgacaaatggacgctgcttccaacgaacatgagcacggggcggagctatgcaggtgtt
gccgtgattcacaagtccttgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (27)   
   RefSeq(nuc) (3)   
   GenBank (12)   
   EMBL (12)   
3D Structure (3)   
   PDB (3)   
Protein domain (10)   
   Pfam (10)   
All databases (70)   

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