KEGG   Homo sapiens (human): 27Help
Entry
27                CDS       T01001                                 

Gene name
ABL2, ABLL, ARG
Definition
ABL proto-oncogene 2, non-receptor tyrosine kinase (EC:2.7.10.2)
Orthology
K08887  
abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
ErbB signaling pathway
Ras signaling pathway
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    27 (ABL2)
   04012 ErbB signaling pathway
    27 (ABL2)
 Human Diseases
  Cardiovascular diseases
   05416 Viral myocarditis
    27 (ABL2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     27 (ABL2)
Protein kinases [BR:hsa01001]
 Tyrosine protein kinases
  Abl family
   27 (ABL2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
1q25.2
AA seq 1064 aa AA seqDB search
MVLGTVLLPPNSYGRDQDTSLCCLCTEASESALPDLTDHFASCVEDGFEGDKTGGSSPEA
LHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLR
VLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSF
LVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGL
VTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVA
VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRE
CNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT
GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY
DLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEE
LGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPGFIRGAQ
ASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREM
ENQPHKKYELTGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSE
ESAAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGAR
LGMAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKF
KLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSET
QEGGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEK
ISADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFRE
AVSKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR
NT seq 3195 nt NT seq  +upstreamnt  +downstreamnt
atggtccttgggacagttctccttccacctaatagttatggcagagatcaggacacttca
ctttgctgcctgtgcactgaggcctcagaatctgctctacccgacttaacagatcacttt
gccagctgtgtggaggatggatttgagggagacaagactggaggcagtagtccagaagct
ttgcatcgtccctatggttgtgatgttgaaccccaggcactaaatgaggctatcaggtgg
agctccaaggagaacttgctcggagccactgagagtgaccctaatctcttcgttgcactt
tatgattttgtagcaagtggtgataacacactcagcatcactaaaggtgaaaagctacga
gtccttggttacaaccagaatggtgagtggagtgaagttcgctctaagaatgggcagggc
tgggtgccaagcaactacatcaccccagtgaacagcctggaaaaacactcctggtaccat
ggacctgtgtcacgcagtgcagctgagtatctgctcagcagtctaatcaatggcagcttc
ctggtgcgagaaagtgagagtagccctgggcagctgtccatctcgctcaggtacgaggga
cgtgtgtatcactacaggatcaataccactgcagatggcaaggtgtatgtgactgctgag
agccgcttcagcaccttggcagagcttgtacaccatcactccacagtggctgatgggctg
gtgacaacattacactacccagcacccaagtgtaataagcctacagtctatggtgtgtcc
cccatccacgacaaatgggaaatggagcgaacagatattaccatgaagcacaaacttggg
ggcggtcagtatggagaggtttacgttggcgtctggaagaaatacagccttacagttgct
gtgaaaacattgaaggaagataccatggaggtagaagaattcctgaaagaagctgcagta
atgaaggaaatcaagcatcctaatctggtacaacttttaggtgtgtgtactttggagcca
ccattttacattgtgactgaatacatgccatacgggaatttgctggattacctccgagaa
tgcaaccgagaagaggtgactgcagttgtgctgctctacatggccactcagatttcttct
gcaatggagtacttagagaagaagaatttcatccatagagatcttgcagctcgtaactgc
ctagtgggagaaaaccatgtggtaaaagtggctgactttggcttaagtagattgatgact
ggagacacttatactgctcatgctggagccaaatttcctattaagtggacagcaccagag
agtcttgcctacaataccttctcaattaaatctgacgtctgggcttttggggtattgttg
tgggaaattgctacctatggaatgtcaccatatccaggtattgacctgtctcaggtctat
gacctactagaaaaaggatatcgaatggaacagcctgagggatgcccccctaaggtttat
gaacttatgagagcatgctggaagtggagccctgccgataggccctcttttgctgaaaca
caccaagcttttgaaaccatgttccatgactccagcatttctgaagaggtagctgaggag
cttgggagagccgcctcctcgtcatctgttgttccatacctgccccggctacctatactt
ccttccaagactcggacactgaagaaacaggtggagaacaaggagaacattgaaggggca
caagatgccacagaaaattctgcttccagtttagcaccagggttcatcagaggtgcacag
gcctctagtggatccccagcactgcctcgaaagcaaagagacaagtcacccagcagcctc
ttggaagatgccaaagagacatgcttcaccagggataggaaggggggcttcttcagctcc
ttcatgaagaagagaaatgctcctacaccccccaaacgcagcagctccttccgagaaatg
gagaatcagccccataagaaatacgaactcacggggcttccagagcaggataggatggca
atgacccttcccaggaactgccagaggtccaaactccagctggaaaggacagtgtccacc
tcttctcagccagaagagaatgtggacagggccaatgacatgcttccaaaaaaatcagag
gaaagtgctgctccaagcagggagagaccaaaagccaagttattgcccagaggagccaca
gctcttcctctcagaacaccctctggggatctagccattacagagaaggaccctccaggg
gtgggagtggctggagtggcagctgcccccaagggtaaagagaagaatggtggggcacga
cttgggatggctggagttccagaggatggagagcagccgggctggccttctccagccaag
gctgcccccgtcctcccaaccactcacaaccacaaagtgccagtccttatctcacccact
ctgaaacacactccagctgacgtgcagctcattggcacagactctcaggggaataaattc
aagctcttatctgagcatcaggtcacatcctctggagacaaggaccgaccccgacgggta
aaaccaaagtgtgccccacccccaccaccagtgatgagactactgcagcatccgtccatc
tgctcagaccctacagaagagccaactgccctaactgcaggacagtccacatcagaaaca
caggaaggaggaaagaaggcagctctgggcgcagtgcccatcagtgggaaagctgggagg
ccagtgatgcctccacctcaagtgcctctgcccacatcttccatctcgccagccaaaatg
gccaatggcacagcaggtactaaagtggctctgagaaaaaccaaacaggccgctgagaaa
atctcagcagacaaaatcagcaaagaggccctgctggaatgtgctgacctactgtccagt
gcactcacggaacctgtgcccaacagccagctggtagacactggacaccagctgcttgac
tactgctcaggctatgtggactgcatccctcaaactcgcaacaaatttgccttccgagag
gctgtgagcaaactggaactcagcctgcaggagctacaggtttcttcagcagctgctggt
gtgcccgggacaaaccctgtccttaataacttattgtcatgtgtacaggaaatcagtgat
gtggtgcagaggtag

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