KEGG T01001: 27

Homo sapiens (human): 27

Entry

27 CDS T01001

Gene name

ABL2, ABLL, ARG

Definition

v-abl Abelson murine leukemia viral oncogene homolog 2 (EC:2.7.10.2)

Orthology

K08887

abelson tyrosine-protein kinase 2 [EC:2.7.10.2]

Organism

hsa Homo sapiens (human)

Pathway

hsa04012	ErbB signaling pathway
hsa05416	Viral myocarditis

Class

Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:hsa04012]
Human Diseases; Cardiovascular diseases; Viral myocarditis [PATH:hsa05416]

SSDB

Motif

Pfam:

Pkinase_Tyr Pkinase F_actin_bind SH2 SH3_1 SH3_9 SH3_2 SH3_3 Kinase-like SH3_6

Other DBs

NCBI-GI:

209862772

NCBI-GeneID:

OMIM:

164690

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

4EIH 3HMI 3GVU 2XYN 2KK1 2ECD

Position

1q25.2

AA seq 1064 aa
MVLGTVLLPPNSYGRDQDTSLCCLCTEASESALPDLTDHFASCVEDGFEGDKTGGSSPEA
LHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLR
VLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSF
LVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGL
VTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVA
VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRE
CNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT
GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY
DLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEE
LGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPGFIRGAQ
ASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREM
ENQPHKKYELTGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSE
ESAAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGAR
LGMAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKF
KLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSET
QEGGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEK
ISADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFRE
AVSKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR

NT seq 3195 nt +upstreamnt +downstreamnt
atggtccttgggacagttctccttccacctaatagttatggcagagatcaggacacttca
ctttgctgcctgtgcactgaggcctcagaatctgctctacccgacttaacagatcacttt
gccagctgtgtggaggatggatttgagggagacaagactggaggcagtagtccagaagct
ttgcatcgtccctatggttgtgatgttgaaccccaggcactaaatgaggctatcaggtgg
agctccaaggagaacttgctcggagccactgagagtgaccctaatctcttcgttgcactt
tatgattttgtagcaagtggtgataacacactcagcatcactaaaggtgaaaagctacga
gtccttggttacaaccagaatggtgagtggagtgaagttcgctctaagaatgggcagggc
tgggtgccaagcaactacatcaccccagtgaacagcctggaaaaacactcctggtaccat
ggacctgtgtcacgcagtgcagctgagtatctgctcagcagtctaatcaatggcagcttc
ctggtgcgagaaagtgagagtagccctgggcagctgtccatctcgctcaggtacgaggga
cgtgtgtatcactacaggatcaataccactgcagatggcaaggtgtatgtgactgctgag
agccgcttcagcaccttggcagagcttgtacaccatcactccacagtggctgatgggctg
gtgacaacattacactacccagcacccaagtgtaataagcctacagtctatggtgtgtcc
cccatccacgacaaatgggaaatggagcgaacagatattaccatgaagcacaaacttggg
ggcggtcagtatggagaggtttacgttggcgtctggaagaaatacagccttacagttgct
gtgaaaacattgaaggaagataccatggaggtagaagaattcctgaaagaagctgcagta
atgaaggaaatcaagcatcctaatctggtacaacttttaggtgtgtgtactttggagcca
ccattttacattgtgactgaatacatgccatacgggaatttgctggattacctccgagaa
tgcaaccgagaagaggtgactgcagttgtgctgctctacatggccactcagatttcttct
gcaatggagtacttagagaagaagaatttcatccatagagatcttgcagctcgtaactgc
ctagtgggagaaaaccatgtggtaaaagtggctgactttggcttaagtagattgatgact
ggagacacttatactgctcatgctggagccaaatttcctattaagtggacagcaccagag
agtcttgcctacaataccttctcaattaaatctgacgtctgggcttttggggtattgttg
tgggaaattgctacctatggaatgtcaccatatccaggtattgacctgtctcaggtctat
gacctactagaaaaaggatatcgaatggaacagcctgagggatgcccccctaaggtttat
gaacttatgagagcatgctggaagtggagccctgccgataggccctcttttgctgaaaca
caccaagcttttgaaaccatgttccatgactccagcatttctgaagaggtagctgaggag
cttgggagagccgcctcctcgtcatctgttgttccatacctgccccggctacctatactt
ccttccaagactcggacactgaagaaacaggtggagaacaaggagaacattgaaggggca
caagatgccacagaaaattctgcttccagtttagcaccagggttcatcagaggtgcacag
gcctctagtggatccccagcactgcctcgaaagcaaagagacaagtcacccagcagcctc
ttggaagatgccaaagagacatgcttcaccagggataggaaggggggcttcttcagctcc
ttcatgaagaagagaaatgctcctacaccccccaaacgcagcagctccttccgagaaatg
gagaatcagccccataagaaatacgaactcacggggcttccagagcaggataggatggca
atgacccttcccaggaactgccagaggtccaaactccagctggaaaggacagtgtccacc
tcttctcagccagaagagaatgtggacagggccaatgacatgcttccaaaaaaatcagag
gaaagtgctgctccaagcagggagagaccaaaagccaagttattgcccagaggagccaca
gctcttcctctcagaacaccctctggggatctagccattacagagaaggaccctccaggg
gtgggagtggctggagtggcagctgcccccaagggtaaagagaagaatggtggggcacga
cttgggatggctggagttccagaggatggagagcagccgggctggccttctccagccaag
gctgcccccgtcctcccaaccactcacaaccacaaagtgccagtccttatctcacccact
ctgaaacacactccagctgacgtgcagctcattggcacagactctcaggggaataaattc
aagctcttatctgagcatcaggtcacatcctctggagacaaggaccgaccccgacgggta
aaaccaaagtgtgccccacccccaccaccagtgatgagactactgcagcatccgtccatc
tgctcagaccctacagaagagccaactgccctaactgcaggacagtccacatcagaaaca
caggaaggaggaaagaaggcagctctgggcgcagtgcccatcagtgggaaagctgggagg
ccagtgatgcctccacctcaagtgcctctgcccacatcttccatctcgccagccaaaatg
gccaatggcacagcaggtactaaagtggctctgagaaaaaccaaacaggccgctgagaaa
atctcagcagacaaaatcagcaaagaggccctgctggaatgtgctgacctactgtccagt
gcactcacggaacctgtgcccaacagccagctggtagacactggacaccagctgcttgac
tactgctcaggctatgtggactgcatccctcaaactcgcaacaaatttgccttccgagag
gctgtgagcaaactggaactcagcctgcaggagctacaggtttcttcagcagctgctggt
gtgcccgggacaaaccctgtccttaataacttattgtcatgtgtacaggaaatcagtgat
gtggtgcagaggtag

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (9)   
   UniProt (1)   
   RefSeq(pep) (8)   
DNA sequence (38)   
   RefSeq(nuc) (8)   
   GenBank (15)   
   EMBL (15)   
3D Structure (6)   
   PDB (6)   
Protein domain (10)   
   Pfam (10)   
All databases (84)   

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