KEGG   Homo sapiens (human): 27165Help
Entry
27165             CDS       T01001                                 

Gene name
GLS2, GA, GLS, LGA, hLGA
Definition
glutaminase 2 (liver, mitochondrial) (EC:3.5.1.2)
Orthology
K01425  
glutaminase [EC:3.5.1.2]
Organism
hsa  Homo sapiens (human)
Pathway
Alanine, aspartate and glutamate metabolism
Arginine and proline metabolism
D-Glutamine and D-glutamate metabolism
Metabolic pathways
Glutamatergic synapse
GABAergic synapse
Proximal tubule bicarbonate reclamation
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    27165 (GLS2)
   00330 Arginine and proline metabolism
    27165 (GLS2)
  Metabolism of other amino acids
   00471 D-Glutamine and D-glutamate metabolism
    27165 (GLS2)
 Organismal Systems
  Excretory system
   04964 Proximal tubule bicarbonate reclamation
    27165 (GLS2)
  Nervous system
   04724 Glutamatergic synapse
    27165 (GLS2)
   04727 GABAergic synapse
    27165 (GLS2)
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    27165 (GLS2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.2  glutaminase
     27165 (GLS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
12q13.3
AA seq 326 aa AA seqDB search
MNTWVSAMPRKVIFPLLPTPTPPTSSTKLGVCFRFQSEKETGDRNYAIGYYLKEKKCFPK
GVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSC
GMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSHRGTSFCQKLVS
LFNFHNYDNLRHCARKLDPRREGAEIRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKD
YDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLLQDYQ
DSYTLSETQAEAAAEALSKENLESMV
NT seq 981 nt NT seq  +upstreamnt  +downstreamnt
atgaatacatgggtttcagcaatgccacggaaggtaatttttccccttctcccaacaccc
actcctccaacttcaagtactaaattgggtgtttgcttcagattccagtcagagaaggaa
acaggggatcggaattatgccatcggctattatctcaaggaaaagaagtgctttcctaag
ggggtggacatgatggctgcccttgatctctacttccagctgtgttctgtggaggtcact
tgtgaatcaggcagtgtcatggcagccaccctcgccaacggtgggatctgccccatcaca
ggcgagagtgtgctgagtgctgaagcagtgcgcaacaccctcagcctcatgcattcctgc
ggcatgtatgacttctctggccagtttgccttccacgtgggcctgccagccaagtcagct
gtatcaggagccatcctcctggtggtacccaatgtcatgggaatgatgtgcctgtcaccc
ccattggacaagctggggaacagccatagggggaccagcttctgccagaagttggtgtct
ctcttcaatttccacaactatgacaacctgaggcactgtgctcggaagttagacccacgg
cgtgaaggggcagaaattcggaacaagactgtggtcaacctgttatttgctgcctatagt
ggcgatgtctcagctcttcgaaggtttgccttgtcagccatggatatggaacagaaagac
tatgactcgcgcacagctctgcatgttgctgcagctgaaggacacatcgaagttgttaaa
ttcctgatcgaggcttgcaaagtgaatccttttgccaaggacaggtggggcaacattccc
ctggatgatgctgtgcagttcaaccatctggaggtggtcaaactgcttcaagattaccag
gactcctacacactctctgaaactcaggctgaggcagcagctgaggccctgtccaaagag
aacttagaaagcatggtatga

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