| Entry |
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| Gene name |
GLUD1, GDH, GDH1, GLUD
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| Definition |
glutamate dehydrogenase 1 (EC:1.4.1.3)
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| Orthology |
| glutamate dehydrogenase (NAD(P)+) [EC: 1.4.1.3] |
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| Organism |
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| Pathway |
| Alanine, aspartate and glutamate metabolism | | Arginine and proline metabolism | | D-Glutamine and D-glutamate metabolism | | Metabolic pathways | | Proximal tubule bicarbonate reclamation |
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| Disease |
| Familial hyperinsulinemic hypoglycemia (HHF) |
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| Class |
Metabolism; Amino acid metabolism; Alanine, aspartate and glutamate metabolism [PATH: hsa00250]
Metabolism; Amino acid metabolism; Arginine and proline metabolism [PATH: hsa00330]
Metabolism; Metabolism of other amino acids; D-Glutamine and D-glutamate metabolism [PATH: hsa00471]
Organismal Systems; Excretory system; Proximal tubule bicarbonate reclamation [PATH: hsa04964]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Structure |
PDB: |
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| Position |
10q23.3
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| AA seq |
558 aa  
MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADR
EDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSF
PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG
GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTY
ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG
DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG
FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER
NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK
HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV
NAIEKVFKVYNEAGVTFT |
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| NT seq |
1677 nt  +upstreamnt +downstreamnt
atgtaccgctacctgggcgaagcgctgttgctgtcccgggccgggcccgctgccctgggc
tcggcgtccgccgactcggccgcgttgctgggctgggcccggggacagcccgccgccgcc
ccgcagccggggctggcattggccgcccggcgccactacagcgaggcggtggccgaccgc
gaggacgaccccaacttcttcaagatggtggagggcttcttcgatcgcggcgccagcatc
gtggaggacaagctggtggaggacctgaggacccgggagagcgaggagcagaagcggaac
cgggtgcgcggcatcctgcggatcatcaagccctgcaaccatgtgctgagtctctccttc
cccatccggcgcgacgacggctcctgggaggtcatcgaaggctaccgggcccagcacagc
cagcaccgcacgccctgcaagggaggtatccgttacagcactgatgtgagtgtagatgaa
gtaaaagctttggcttctctgatgacatacaagtgtgcagtggttgatgtgccgtttggg
ggtgctaaagctggtgttaagatcaatcccaagaactatactgataatgaattggaaaag
atcacaaggaggttcaccatggagctagcaaaaaagggctttattggtcctggcattgat
gtgcctgctccagacatgagcacaggtgagcgggagatgtcctggatcgctgatacctat
gccagcaccatagggcactatgatattaatgcacacgcctgtgttactggtaaacccatc
agccaagggggaatccatggacgcatctctgctactggccgtggtgtcttccatgggatt
gaaaatttcatcaatgaagcttcttacatgagcattttaggaatgacaccagggtttgga
gataaaacatttgttgttcagggatttggtaatgtgggcctacactctatgagatattta
catcgttttggtgctaaatgtattgctgttggtgagtctgatgggagtatatggaatcca
gatggtattgacccaaaggaactggaagacttcaaattgcaacatgggtccattctgggc
ttccccaaggcaaagccctatgaaggaagcatcttggaggccgactgtgacatactgatc
ccagctgccagtgagaagcagttgaccaaatccaacgcacccagagtcaaagccaagatc
attgctgaaggtgccaatgggccaacaactccagaagctgacaagatcttcctggagaga
aacattatggttattccagatctctacttgaatgctggaggagtgacagtatcttacttt
gagtggctgaagaatctaaatcatgtcagctatggccgtttgaccttcaaatatgaaagg
gattctaactaccacttgctcatgtctgttcaagagagtttagaaagaaaatttggaaag
catggtggaactattcccattgtacccacggcagagttccaagacaggatatcgggtgca
tctgagaaagacatcgtgcactctggcttggcatacacaatggagcgttctgccaggcaa
attatgcgcacagccatgaagtataacctgggattggacctgagaacagctgcctatgtt
aatgccattgagaaagtcttcaaagtgtacaatgaagctggtgtgaccttcacatag |
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