KEGG   Homo sapiens (human): 2746Help
Entry
2746              CDS       T01001                                 

Gene name
GLUD1, GDH, GDH1, GLUD
Definition
(RefSeq) glutamate dehydrogenase 1
  KO
K00261  
glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
Organism
hsa  Homo sapiens (human)
Pathway
Arginine biosynthesis
Alanine, aspartate and glutamate metabolism
D-Glutamine and D-glutamate metabolism
Nitrogen metabolism
Metabolic pathways
Carbon metabolism
Necroptosis
Proximal tubule bicarbonate reclamation
Disease
H01267  
Familial hyperinsulinemic hypoglycemia (HHF)
H01400  
Secondary hyperammonemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Energy metabolism
   00910 Nitrogen metabolism
    2746 (GLUD1)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    2746 (GLUD1)
   00220 Arginine biosynthesis
    2746 (GLUD1)
  Metabolism of other amino acids
   00471 D-Glutamine and D-glutamate metabolism
    2746 (GLUD1)
 Cellular Processes
  Cell growth and death
   04217 Necroptosis
    2746 (GLUD1)
 Organismal Systems
  Excretory system
   04964 Proximal tubule bicarbonate reclamation
    2746 (GLUD1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.3  glutamate dehydrogenase [NAD(P)+]
     2746 (GLUD1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   2746 (GLUD1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P00367(Tbio)
UniProt: 
Structure
PDB: 

Jmol
Position
10q23.2
AA seq 558 aa AA seqDB search
MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADR
EDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSF
PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG
GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTY
ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG
DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG
FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER
NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK
HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV
NAIEKVFKVYNEAGVTFT
NT seq 1677 nt NT seq  +upstreamnt  +downstreamnt
atgtaccgctacctgggcgaagcgctgttgctgtcccgggccgggcccgctgccctgggc
tcggcgtccgccgactcggccgcgttgctgggctgggcccggggacagcccgccgccgcc
ccgcagccggggctggcattggccgcccggcgccactacagcgaggcggtggccgaccgc
gaggacgaccccaacttcttcaagatggtggagggcttcttcgatcgcggcgccagcatc
gtggaggacaagctggtggaggacctgaggacccgggagagcgaggagcagaagcggaac
cgggtgcgcggcatcctgcggatcatcaagccctgcaaccatgtgctgagtctctccttc
cccatccggcgcgacgacggctcctgggaggtcatcgaaggctaccgggcccagcacagc
cagcaccgcacgccctgcaagggaggtatccgttacagcactgatgtgagtgtagatgaa
gtaaaagctttggcttctctgatgacatacaagtgtgcagtggttgatgtgccgtttggg
ggtgctaaagctggtgttaagatcaatcccaagaactatactgataatgaattggaaaag
atcacaaggaggttcaccatggagctagcaaaaaagggctttattggtcctggcattgat
gtgcctgctccagacatgagcacaggtgagcgggagatgtcctggatcgctgatacctat
gccagcaccatagggcactatgatattaatgcacacgcctgtgttactggtaaacccatc
agccaagggggaatccatggacgcatctctgctactggccgtggtgtcttccatgggatt
gaaaatttcatcaatgaagcttcttacatgagcattttaggaatgacaccagggtttgga
gataaaacatttgttgttcagggatttggtaatgtgggcctacactctatgagatattta
catcgttttggtgctaaatgtattgctgttggtgagtctgatgggagtatatggaatcca
gatggtattgacccaaaggaactggaagacttcaaattgcaacatgggtccattctgggc
ttccccaaggcaaagccctatgaaggaagcatcttggaggccgactgtgacatactgatc
ccagctgccagtgagaagcagttgaccaaatccaacgcacccagagtcaaagccaagatc
attgctgaaggtgccaatgggccaacaactccagaagctgacaagatcttcctggagaga
aacattatggttattccagatctctacttgaatgctggaggagtgacagtatcttacttt
gagtggctgaagaatctaaatcatgtcagctatggccgtttgaccttcaaatatgaaagg
gattctaactaccacttgctcatgtctgttcaagagagtttagaaagaaaatttggaaag
catggtggaactattcccattgtacccacggcagagttccaagacaggatatcgggtgca
tctgagaaagacatcgtgcactctggcttggcatacacaatggagcgttctgccaggcaa
attatgcgcacagccatgaagtataacctgggattggacctgagaacagctgcctatgtt
aatgccattgagaaagtcttcaaagtgtacaatgaagctggtgtgaccttcacatag

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