KEGG   Homo sapiens (human): 28227
Entry
28227             CDS       T01001                                 
Symbol
PPP2R3B, NYREN8, PPP2R3L, PPP2R3LY, PR48, PR70
Name
(RefSeq) protein phosphatase 2 regulatory subunit B''beta
  KO
K11583  serine/threonine-protein phosphatase 2A regulatory subunit B''
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04660  T cell receptor signaling pathway
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06166  Human papillomavirus (HPV)
nt06530  PI3K signaling
nt06537  TCR/BCR signaling
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
N01579  CD80/CD86-CTLA4-PP2A signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    28227 (PPP2R3B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    28227 (PPP2R3B)
   04151 PI3K-Akt signaling pathway
    28227 (PPP2R3B)
   04152 AMPK signaling pathway
    28227 (PPP2R3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    28227 (PPP2R3B)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    28227 (PPP2R3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    28227 (PPP2R3B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    28227 (PPP2R3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    28227 (PPP2R3B)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    28227 (PPP2R3B)
   03036 Chromosome and associated proteins [BR:hsa03036]
    28227 (PPP2R3B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     28227 (PPP2R3B)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Protein phosphatase 2A
     28227 (PPP2R3B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     28227 (PPP2R3B)
SSDB
Motif
Pfam: EF-hand_13 P2R3B_EF-hand EF-hand_7 EF-hand_5 EF-hand_6 EF-hand_1 EF-hand_8
Other DBs
NCBI-GeneID: 28227
NCBI-ProteinID: NP_037371
OMIM: 300339
HGNC: 13417
Ensembl: ENSG00000167393 ENSG00000292327
UniProt: Q9Y5P8
Structure
Position
X:complement(333933..386907), Y:complement(333933..386907)
AA seq 575 aa
MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPT
APLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPA
TSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACGCPLYWKG
PLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQD
VVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE
EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAV
TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQ
CRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDH
EQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDGFEAELSPVEQKLSA
LRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
NT seq 1728 nt   +upstreamnt  +downstreamnt
atgccgcccggcaaagtgctgcagccggtcctgaagatgaaggtggacgagctgttcctg
tactggctcagcgaggccagcacgcagcggatgctgcaggactgcctgcgccggatcaag
gcgcccgggcgggaccagccgaccccgggggacggggagcagcccggggcctggcccaca
gccccgctcgccgccccccggcccagcgggctcgaacccccgggaacccccgggccgggc
cctgcgctgcccctgggcgccgcctccagccccaggaacgcgccccacgttcgaggcacc
cgtagatccgcagggacgagagtagttcagacacggaaagaagagcctctgcccccggcc
acgagccaaagcattccgaccttctacttccccagaggacgcccgcaggactccgtcaac
gtggatgccgtcatcagcaagatcgagagcaccttcgcccggttcccccacgagagggcc
accatggatgacatgggcctggtggccaaggcctgcggctgccccctctactggaagggg
ccgctcttctatggcgccggcggggagcgcacgggctccgtgtccgtccacaagttcgtc
gccatgtggagaaaaatcctccagaactgccacgacgacgcggccaagttcgtccatctg
ctcatgagccccggctgcaactacctggtgcaggaggactttgtccccttcttgcaggac
gtggtgaacacgcacccggggctgtcgttcctgaaggaggcgtccgagttccactcgcgc
tacatcaccacggtcatccagcggatcttctacgccgtgaaccggtcctggtccggcagg
atcacctgcgccgagctgcggaggagctccttcctgcagaatgtggcgctgctggaggag
gaggcggacatcaaccagctgaccgaattcttctcgtacgagcatttctacgtcatctac
tgcaagttctgggagctggacacggaccacgacctgctcatcgacgcggacgacctggcg
cggcacaatgaccacgccctttctaccaagatgatagacaggatcttctcaggagcagtc
acacgaggcagaaaagtgcagaaggaagggaagatcagctatgccgactttgtctggttt
ttgatctctgaggaagacaaaaaaacaccgaccagcatcgagtactggttccgctgcatg
gacctggacggggacggcgccctgtccatgttcgagctcgagtacttctacgaggagcag
tgccgaaggctggacagcatggccatcgaggccctgcccttccaggactgcctctgccag
atgctggacctggtcaagccgaggactgaagggaagatcacgctgcaggacctgaagcgc
tgcaagctggctaacgtcttcttcgacaccttcttcaacatcgagaagtacctcgaccac
gagcagaaagagcagatctccctgctcagggacggtgacagcggcggccccgagctctcg
gactgggagaagtacgcggccgaggagtacgacatcctggtggccgaggagactgcggga
gagccctgggaggacgggttcgaggccgagctcagccctgtggagcagaagctgagtgcg
ctgcgctccccgctggcccagaggcccttcttcgaggcgccctcaccgctgggcgccgtg
gacctgtacgagtacgcatgcggggacgaggacctggagccgctgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Network (6)   
   KEGG NETWORK (6)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (2)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (41)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (39)   
DNA sequence (76)   
   RefSeq(nuc) (40)   
   GenBank (18)   
   EMBL (18)   
3D Structure (3)   
   PDB (3)   
Protein domain (7)   
   Pfam (7)   
All databases (162)   

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