KEGG   Homo sapiens (human): 284086Help
Entry
284086            CDS       T01001                                 

Gene name
NEK8, JCK, NEK12A, NPHP9, RHPD2
Definition
(RefSeq) NIMA related kinase 8 (EC:2.7.11.1)
  KO
K08857  
NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Disease
H00537  
Nephronophthisis-medullary cystic kidney disease
Brite
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     284086 (NEK8)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: Other group
  NEK family
   284086 (NEK8)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     284086 (NEK8)
Chromosome [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Kinases and associated factors
    284086 (NEK8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
UniProt: 
Position
17q11.1
AA seq 692 aa AA seqDB search
MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH
PNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVH
THLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPY
NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLS
LEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRAEKSVAPSNTGSRTTSVRCRGIPR
GPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPP
LGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLTDRGIIMTFGSGSN
GCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTR
ESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVP
HQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRG
SRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQL
DETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
NT seq 2079 nt NT seq  +upstreamnt  +downstreamnt
atggagaagtacgagcggatccgagtggtggggagaggtgccttcgggattgtgcacctg
tgcctgcgaaaggctgaccagaagctggtgatcatcaagcagattccagtggaacagatg
accaaggaagagcggcaggcagcccagaatgagtgccaggtcctcaagctgctcaaccac
cccaatgtcattgagtactacgagaacttcctggaagacaaagcccttatgatcgccatg
gaatatgcaccaggcggcactctggctgagttcatccaaaagcgctgtaattccctgctg
gaggaggagaccatcctgcacttcttcgtgcagatcctgcttgcactgcatcatgtgcac
acccacctcatcctgcaccgagacctcaagacccagaacatcctgcttgacaaacaccgc
atggtcgtcaagatcggtgatttcggcatctccaagatccttagcagcaagagcaaggcc
tacacggtggtgggtaccccatgctatatctcccctgagctgtgtgagggcaagccctac
aaccagaagagtgacatctgggccctgggctgtgtcctctacgagctggccagcctcaag
agggctttcgaggctgcgaacttgccagcactggtgctgaagatcatgagtggcaccttt
gcacctatctctgaccggtacagccctgagcttcgccagctggtcctgagtctactcagc
ctggagcctgcccagcggccaccactcagccacatcatggcacagcccctctgcatccgt
gccctcctcaacctccacaccgacgtgggcagtgtccgcatgcggagggcagagaagtcc
gtggcccccagcaacacagggagcaggaccaccagtgtccgctgcagaggtatcccccgg
ggacctgtgaggccagccatcccaccaccactgtcgtcagtgtatgcctggggtggtggg
ctgggcacccccctgcggctgccaatgctcaacacagaggtggtccaggtggcagctggg
cgcacgcagaaagccggcgtcacgcgctctgggcgtctcatcctgtgggaggccccaccc
ctaggtgcaggcggaggcagtctccttcctggggcagtggagcagccacagccccagttc
atctcgcgtttcctggagggccagtcgggtgtgaccatcaagcacgtggcctgtggggac
ttcttcactgcctgcctgactgacagaggcatcatcatgacattcggcagcggcagcaat
gggtgcctaggccatggcagcctcactgacatcagccagcccaccattgtggaggctttg
ctgggctatgaaatggtgcaggtggcctgtggggcctctcacgtgctggccctgtccact
gagcgagaactatttgcctggggccgtggagacagcggcagactggggctaggcaccagg
gagtcccacagctgcccccagcaggtgcccatgcccccaggacaggaagctcagcgagtt
gtatgtggtatcgattcctccatgatcctcactgtgcctggccaagccctagcctgtggg
agcaacaggttcaacaagctgggcctggaccacctctccctgggggaggagcctgtcccc
caccagcaagtggaggaggccctgagcttcacactactaggctctgcacccctggaccag
gagcctctgctgagtatagacctgggcactgctcactcagctgctgtgactgcctcgggt
gattgctacacttttggcagcaatcagcacggacagttgggcaccaatactcgccgaggc
agtcgggcaccctgtaaggtccaaggccttgagggcatcaagatggcaatggtagcctgt
ggggatgccttcactgtagctattggggcagagagcgaagtgtactcttggggcaaaggg
gcgcgaggtcgattgggaaggagggatgaggatgccggactccctcggccagtgcagttg
gatgagacacacccttacacggtgacttccgtgtcctgttgccatggaaacaccctcctg
gctgttcgatcggtcacagatgagccggtccccccctga

DBGET integrated database retrieval system