KEGG   Homo sapiens (human): 2889Help
Entry
2889              CDS       T01001                                 

Gene name
RAPGEF1, C3G, GRF2
Definition
Rap guanine nucleotide exchange factor (GEF) 1
Orthology
K06277  
Rap guanine nucleotide exchange factor 1
Organism
hsa  Homo sapiens (human)
Pathway
Rap1 signaling pathway
Focal adhesion
Neurotrophin signaling pathway
Insulin signaling pathway
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    2889 (RAPGEF1)
 Cellular Processes
  Cellular commiunity
   04510 Focal adhesion
    2889 (RAPGEF1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    2889 (RAPGEF1)
  Nervous system
   04722 Neurotrophin signaling pathway
    2889 (RAPGEF1)
 Human Diseases
  Cancers
   05211 Renal cell carcinoma
    2889 (RAPGEF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
9q34.3
AA seq 1077 aa AA seqDB search
MDTDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKIPEKPVNKEATDRFLPEG
YPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKV
LEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSE
DKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGPAELPLTDRE
VEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPPALPPKKRQSAPSPTRV
AVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKS
DEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQTAWNLSPLPESLGE
SGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRSAASQTADGSGCRVSYER
HPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVEFVGDFTAPESTGDPEKP
PPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKNKLLMEVYGFSDSFSGVD
SVQELAPPPALPPKQRQLEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSPDALESAQ
SEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFL
TTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILK
LLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARPGTLHDFH
SHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQ
EKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTL
IDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILD
SMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt
atggacacagactctcagcgttctcatctctcttccttcaccatgaagctgatggacaaa
ttccactcacccaaaatcaagagaacgccatcaaagaagggaaaaccagctgaggtgtcc
gtaaagattccagagaagcctgtgaacaaagaggcaacagacagatttctaccagagggc
taccctctccccttggatctggagcagcaggcagtagaatttatgtccaccagtgctgtg
gcttccaggtctcaaaggcagaagaacctgagctggctggaggagaaagagaaggaagtt
gtcagtgccctgcgctactttaagaccattgtggacaaaatggcaattgataagaaggta
ctggagatgcttccagggtcagccagcaaggtgctggaggccatcttacccctggtgcag
aacgatcctcgaattcagcacagctcagccctctcttcctgctatagccgagtgtaccaa
agcctcgccaacctcattcgctggtctgaccaagtgatgctggaaggcgtgaactcagaa
gacaaggagatggtgacgactgtgaagggggtcatcaaggctgtgctggatggagtgaag
gagctggtcaggctcaccatcgagaagcagggacgtccgtctccgacgagccccgtgaag
cccagttcccctgccagcaagcctgatggcccagcagagctccccctgacagaccgcgag
gtagagatcctaaacaagacgactgggatgtcacagtcaactgagctcctcccagatgcc
acggatgaagaggtcgcgccccccaagcctcctctgcctggcattcgggtggttgataat
agtcctccaccagcattgccacccaagaaaagacagtcggcgccgtcccctacccgagtg
gctgtggtggcccccatgagccgagccaccagtggctccagtttgcctgttggaatcaat
aggcaggattttgatgttgactgttacgcacagaggcgactgtcaggaggcagccactca
tatggtggagagtcgccccgcctctccccctgcagcagcataggcaagctcagcaagtca
gacgagcagctgtcctctctggacagggacagtgggcagtgctcccggaacacaagctgt
gaaacactagaccactatgatcccgactatgaattcctccagcaagacctctctaacgca
gaccagatacctcagcagacggcctggaaccttagcccgttgccagagtctttgggggag
tctgggtctccatttcttggccctcctttccagctgcctcttggcggccatccccagcca
gacggacctctggccccagggcagcagacagatacgccacctgctctccccgagaagaag
cgcaggagcgcagcctcccagacggcggacggctctggctgcagggtgtcctacgagcgg
catccctcgcagtatgacaacatctctggggaggacctgcagagcacagccccgatccca
tccgtcccctacgcgccctttgctgctattctgccctttcagcatggaggttcctcagcc
cctgtcgaatttgtgggtgattttactgctcctgagtcaaccggtgacccagaaaaacca
cctcctctaccagagaagaaaaacaaacacatgctggcctacatgcagttgctggaggac
tactcggagccgcagccctctatgttctaccagacgccacagaacgagcacatctaccag
cagaagaacaagctcctcatggaggtatacggcttcagcgactccttcagtggggtggac
tccgtgcaggagctggccccgccgcccgccctaccccccaagcagcggcagctggagcca
ccggctgggaaagacggacatcccagagatccctcagcggtcagcggcgtccctgggaag
gacagcagagacggcagtgagagggccccaaagtcaccagatgctctggagtcggctcag
tcggaggaggaagtggacgagctgtccctcattgaccacaacgaaattatgtccaggctg
acgctcaagcaggagggtgatgacgggccggacgtccgcggaggatctggggacatctta
ctggtccatgctactgagactgacaggaaagatttggtgttgtactgcgaggcattcctg
accacctacaggaccttcatctccccagaggagctcatcaagaagctgcagtacagatat
gagaaattctctccctttgccgacacattcaagaagcgcgtcagcaagaacacgttcttc
gtgctggtacgggtggtggatgagctctgcctggtggagttgacagaagagatcctgaag
ctgctgatggaactggtcttccgcctggtgtgcaatggggagctgagcctggcccgtgtg
ctccggaagaacatcctggacaaggtggaccagaagaagctactcaggtgtgccacctcc
agccagcccctggcagcccggggggtagcagccaggccggggaccttgcacgactttcac
agccatgagatagcggagcagctaacgctgctggatgctgagctcttctataaaatagag
attcctgaggttttgctttgggcaaaagagcagaatgaggagaagagccccaacttgacc
cagttcacggagcacttcaacaacatgtcctactgggtccggtccataatcatgttacag
gaaaaggcccaggacagggaacggctgctcttgaagttcatcaagatcatgaagcacttg
cggaagctgaataacttcaactcctacttggccatcctctctgccctggactcggcgccc
atccgcaggctggagtggcagaagcagacttcagagggcctggccgagtactgcacactg
atcgacagctcgtcctccttccgagcctaccgggccgccctctcggaggtggaaccgccg
tgcatcccgtacctggggctgatcctgcaggacctgaccttcgttcacctgggaaaccca
gactacatcgacgggaaagtgaacttctccaagcggtggcagcagttcaacatcctcgac
agcatgcgctgcttccagcaggcgcactatgacatgcggaggaacgacgacattataaac
ttcttcaatgacttcagtgaccacctggctgaggaggccctatgggaactgtctctgaaa
attaaacccaggaacataacaaggagaaaaacagaccgggaagagaagacctag

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