KEGG T01001: 28964

Homo sapiens (human): 28964

Entry

28964 CDS T01001

Gene name

GIT1

Definition

G protein-coupled receptor kinase interacting ArfGAP 1

Orthology

K05737

G protein-coupled receptor kinase interactor 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04144	Endocytosis
hsa04810	Regulation of actin cytoskeleton
hsa05120	Epithelial cell signaling in Helicobacter pylori infection

Class

Cellular Processes; Transport and catabolism; Endocytosis [PATH:hsa04144]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:hsa04810]
Human Diseases; Infectious diseases; Epithelial cell signaling in Helicobacter pylori infection [PATH:hsa05120]

SSDB

Motif

Pfam:

GIT1_C GIT_SHD ArfGap Ank_2 Ank Ank_4 Ank_5 DUF904 Shugoshin_N DUF972 DUF4319

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

17p11.2

AA seq 770 aa
MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTL
LQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKL
PCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQT
LQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPD
HKNGHYIIPQMADRSRQKCMSQSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRE
NDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEA
KRRQQGKSLSSPTDNLELSLRSQSDLDDQHDYDSVASDEDTDQEPLRSTGATRSNRARSM
DSSDLSDGAVTLQEYLELKKALATSEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQL
RQPPGPVPTPPLPSERAEHTPMAPGGSTHRRDRQAFSMYEPGSALKPFGGPPGDELTTRL
QPFHSTELEDDAIYSVHVPAGLYRIRKGVSASAVPFTPSSPLLSCSQEGSRHTSKLSRHG
SGADSDYENTQSGDPLLGLEGKRFLELGKEEDFHPELESLDGDLDPGLPSTEDVILKTEQ
VTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRSSLRLLNASAYR
LQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ

NT seq 2313 nt +upstreamnt +downstreamnt
atgtcccgaaaggggccgcgagcggaggtgtgtgcggactgcagcgccccggaccctggc
tgggcatccatcagcaggggtgtgctggtgtgtgacgagtgctgcagcgtgcaccggagc
ctgggacgccacatctccattgtcaagcaccttcgccacagcgcctggcctcccacgctg
ctgcagatggtgcacacgcttgccagcaacggggccaactccatctgggagcactccctg
ctggaccccgcacaagtgcagagcggccggcgtaaagccaacccccaagacaaagtccac
cccatcaagtcagagttcatcagggccaagtaccagatgctggcatttgtgcacaagctt
ccctgccgggacgatgatggagtcaccgccaaagacctcagcaagcaactacactcgagc
gtgcggacaggcaacctggagacatgtctgcgcctgctctccctgggtgcccaggccaac
ttcttccacccagagaagggcaccacacctctgcacgtggctgccaaggcaggacagaca
ctgcaggccgagctgcttgtagtgtatggggctgaccctggctcccctgatgttaatggc
cgcacacccattgactatgccaggcaggcggggcaccatgagctggcggaaaggctggtt
gagtgccaatatgagctcactgaccggctggccttctacctctgtggacgcaagccggat
cacaagaatgggcattacatcatcccacagatggctgacagatctcggcaaaagtgcatg
tctcagagccttgacttatccgaattggccaaagctgctaagaagaagctgcaggcgctc
agcaaccggctttttgaggaactcgccatggacgtgtatgacgaggtggatcgaagagaa
aatgatgcagtgtggctggctacccaaaaccacagcactctggtgacagagcgcagtgcc
gtgcccttcctgcctgttaacccggaatactcagccacgcggaatcaggggcgacaaaag
ctggcccgctttaatgcccgagagtttgccaccttgatcatcgacattctcagtgaggcc
aagcggagacagcagggcaagagcctgagcagccccacagacaacctcgagctgtctctg
cggagccagagtgacctcgacgaccaacacgactacgacagcgtggcctctgacgaggac
acagaccaggagcccctgcgcagcaccggcgccactcggagcaaccgggcccggagcatg
gactcctcggacttgtctgacggggctgtgacgctgcaggagtacctggagctgaagaag
gccctggctacatcggaggcaaaggtgcagcagctcatgaaggtcaacagtagcctgagc
gacgagctccggaggctgcagcgagagatccacaagctgcaggcggagaacctgcagctc
cggcagcctccagggccggtgcccacacctccactccccagtgaacgggcggaacacaca
cccatggcgccaggcgggagcacacaccgcagggatcgccaggccttttccatgtatgaa
cctggctctgccctgaagccctttgggggcccccctggggacgagctcactacgcggctg
cagcctttccacagcactgagctagaggacgacgccatctattcagtgcacgtccctgct
ggcctttaccggatccggaaaggggtgtctgcctcagctgtgcccttcactccctcctcc
ccgctgctgtcctgctcccaggagggaagccgccacacgagcaagctttcccgccacggc
agtggagccgacagtgactatgagaacacgcaaagtggggacccactgctggggctggaa
gggaagaggtttctagagctgggcaaagaggaagacttccacccagagctggaaagcctg
gatggagacctagatcctgggcttcccagcacagaggatgtcatcttgaagacagagcag
gtcaccaagaacattcaggaactgttgcgggcagcccaggagttcaagcatgacagcttc
gtgccctgctcagagaagatccatttggctgtgaccgagatggcctccctcttcccaaag
aggccagccctggagccagtgcggagctcactgcggctgctcaacgccagcgcctaccgg
ctgcagagtgagtgccggaagacagtgcccccagagcccggcgccccagtggacttccag
ctgctgactcagcaggtgatccagtgcgcctatgacatcgccaaggctgccaagcagctg
gtcaccatcaccacccgagagaagaagcagtga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (13)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (46)   
   RefSeq(nuc) (2)   
   GenBank (22)   
   EMBL (22)   
Protein domain (11)   
   Pfam (11)   
All databases (87)   

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