KEGG T01001: 2946

Homo sapiens (human): 2946

Entry

2946 CDS T01001

Gene name

GSTM2, GST4, GSTM, GSTM2-2, GTHMUS

Definition

glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18)

Orthology

K00799

glutathione S-transferase [EC:2.5.1.18]

Organism

hsa Homo sapiens (human)

Pathway

hsa00480	Glutathione metabolism
hsa00980	Metabolism of xenobiotics by cytochrome P450
hsa00982	Drug metabolism - cytochrome P450
hsa05204	Chemical carcinogenesis

Class

Metabolism; Metabolism of other amino acids; Glutathione metabolism [PATH:hsa00480]
Metabolism; Xenobiotics biodegradation and metabolism; Metabolism of xenobiotics by cytochrome P450 [PATH:hsa00980]
Metabolism; Xenobiotics biodegradation and metabolism; Drug metabolism - cytochrome P450 [PATH:hsa00982]
Human Diseases; Cancers; Chemical carcinogenesis [PATH:hsa05204]

SSDB

Motif

Pfam:

GST_N GST_C GST_C_3 GST_C_2 GST_N_3 GST_N_2 DUF4414 Bromo_TP

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2C4J 1XW5 1HNA 1YKC 3GUR 2AB6 2GTU 3GTU 1HNC 1HNB

Position

1p13.3

AA seq 218 aa
MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF
EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN
LKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK

NT seq 657 nt +upstreamnt +downstreamnt
atgcccatgacactggggtactggaacatccgcgggctggcccattccatccgcctgctc
ctggaatacacagactcaagctacgaggaaaagaagtacacgatgggggacgctcctgat
tatgacagaagccagtggctgaatgaaaaattcaagctgggcctggactttcccaatctg
ccctacttgattgatgggactcacaagatcacccagagcaacgccatcctgcggtacatt
gcccgcaagcacaacctgtgcggggaatcagaaaaggagcagattcgcgaagacattttg
gagaaccagtttatggacagccgtatgcagctggccaaactctgctatgacccagatttt
gagaaactgaaaccagaatacctgcaggcactccctgaaatgctgaagctctactcacag
tttctggggaagcagccatggtttcttggggacaagatcacctttgtggatttcatcgct
tatgatgtccttgagagaaaccaagtatttgagcccagctgcctggatgccttcccaaac
ctgaaggacttcatctcccgatttgagggcttggagaagatctctgcctacatgaagtcc
agccgcttcctcccaagacctgtgttcacaaagatggctgtctggggcaacaagtag

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical substance (44)   
   KEGG COMPOUND (44)   
Chemical reaction (22)   
   KEGG ENZYME (1)   
   KEGG REACTION (21)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (22)   
   RefSeq(nuc) (2)   
   GenBank (10)   
   EMBL (10)   
3D Structure (10)   
   PDB (10)   
Protein domain (8)   
   Pfam (8)   
All databases (131)   

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