KEGG   Homo sapiens (human): 2969
Entry
2969              CDS       T01001                                 
Symbol
GTF2I, BAP135, BTKAP1, DIWS, GTFII-I, IB291, SPIN, TFII-I, WBS, WBSCR6
Name
(RefSeq) general transcription factor IIi
  KO
K03121  transcription initiation factor TFII-I
Organism
hsa  Homo sapiens (human)
Pathway
hsa03022  Basal transcription factors
hsa04022  cGMP-PKG signaling pathway
Disease
H01439  Williams-Beuren syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    2969 (GTF2I)
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    2969 (GTF2I)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    2969 (GTF2I)
   03036 Chromosome and associated proteins [BR:hsa03036]
    2969 (GTF2I)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Others
     2969 (GTF2I)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HDAC complexes
    BRAF-HDAC complex
     2969 (GTF2I)
SSDB
Motif
Pfam: GTF2I
Other DBs
NCBI-GeneID: 2969
NCBI-ProteinID: NP_127492
OMIM: 601679
HGNC: 4659
Ensembl: ENSG00000263001
UniProt: P78347 X5DR09 Q499G6 A8K9W7
Structure
Position
7:74657718..74760692
AA seq 998 aa
MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP
SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD
LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE
RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE
ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR
PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF
ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK
INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE
FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF
RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG
VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN
PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE
GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW
NT seq 2997 nt   +upstreamnt  +downstreamnt
atggcccaagttgcaatgtccaccctccccgttgaagatgaggagtcctcggagagcagg
atggtggtgacattcctcatgtcagctctcgagtccatgtgtaaagaactggccaagtcc
aaagccgaagtggcctgcattgcagtgtatgaaacagacgtgtttgtcgtcggaactgaa
agaggacgtgcttttgtcaataccagaaaggattttcaaaaagattttgtaaaatattgt
gttgaagaagaagaaaaagctgcagagatgcataaaatgaaatctacaacccaggcaaat
cggatgagtgtagatgctgtagaaattgaaacactcagaaaaacagttgaggactatttc
tgcttttgctatgggaaagctttaggcaaatccacagtggtacctgtaccatatgagaag
atgctgcgagaccagtcggctgtggtagtgcaggggcttccggaaggtgttgcctttaaa
caccccgagaactatgatcttgcaaccctgaaatggattttggagaacaaagcagggatt
tcattcatcattaagagaccttttttagagccaaagaagcatgtaggtggtcgtgtgatg
gtaacagatgctgacaggtcaatactatctccaggtggaagttgtggccccatcaaagtg
aaaactgaacccacagaagattctggcatttccctggaaatggcagctgtgacagtaaag
gaagaatcagaagatcctgattattatcaatataacattcaagcaggcccttctgaaact
gatgatgttgatgaaaaacagcccctatcgaagcctttgcaaggaagccaccattcttca
gagggcaatgaaggcacagaaatggaagtaccagcagaagattctactcaacatgtccct
tcagaaacaagtgaggaccctgaagttgaggtgactattgaagatgatgattattctcca
ccgtctaagagaccaaaggccaatgagctaccgcagccaccagtcccggaacccgccaat
gctgggaagcggaaagtgagggagttcaacttcgagaaatggaatgctcgcatcactgat
ctacgtaaacaagttgaagaattgtttgaaaggaaatatgctcaagccataaaagccaaa
ggtccggtgacgatcccgtaccctcttttccagtctcatgttgaagatctttatgtagaa
ggacttcctgaaggaattccttttagaaggccatctacttacggaattcctcgcctggag
aggatattacttgcaaaggaaaggattcgttttgtgattaagaaacatgagcttctgaat
tcaacacgtgaagatttacagcttgataagccagcttcaggagtaaaggaagaatggtat
gccagaatcactaaattaagaaagatggtggatcagcttttctgcaaaaaatttgcggaa
gccttggggagcactgaagccaaggctgtaccgtaccaaaaatttgaggcacacccgaat
gatctgtacgtggaaggactgccagaaaacattcctttccgaagtccctcatggtatgga
atcccaaggctggaaaaaatcattcaagtgggcaatcgaattaaatttgttattaaaaga
ccagaacttctgactcacagtaccactgaagttactcagccaagaacgaatacaccagtc
aaagaagattggaatgtcagaattaccaagctacggaagcaagtggaagagatttttaat
ttgaaatttgctcaagctcttggactcaccgaggcagtaaaagtaccatatcctgtgttt
gaatcaaacccggagttcttgtatgtggaaggcttgccagaggggattcccttccgaagc
cctacctggtttggaattccacgacttgaaaggatcgtccgcgggagtaataaaatcaag
ttcgttgttaaaaaacctgaactagttatttcctacttgcctcctgggatggctagtaaa
ataaacactaaagctttgcagtcccccaaaagaccacgaagtcctgggagtaattcaaag
gttcctgaaattgaggtcaccgtggaaggccctaataacaacaatcctcaaacctcagct
gttcgaaccccgacccagactaacggttctaacgttcccttcaagccacgagggagagag
ttttcctttgaggcctggaatgccaaaatcacggacctaaaacagaaagttgaaaatctc
ttcaatgagaaatgtggggaagctcttggccttaaacaagctgtgaaggtgccgttcgcg
ttatttgagtctttcccggaagacttttatgtggaaggcttacctgagggtgtgccattc
cgaagaccatcgacttttggcattccgaggctggagaagatactcagaaacaaagccaaa
attaagttcatcattaaaaagcccgaaatgtttgagacggcgattaaggagagcacctcc
tctaagagccctcccagaaaaataaattcatcacccaatgttaatactactgcatcaggt
gttgaagaccttaacatcattcaggtgacaattccagatgatgataatgaaagactctcg
aaagttgaaaaagctagacagctaagagaacaagtgaatgacctctttagtcggaaattt
ggtgaagctattggtatgggttttcctgtgaaagttccctacaggaaaatcacaattaac
cctggctgtgtggtagttgatggcatgcccccgggggtgtccttcaaagcccccagctac
ctggaaatcagctccatgagaaggatcttagactctgccgagtttatcaaattcacggtc
attagaccatttccaggacttgtgattaataaccagctggttgatcagagtgagtcagaa
ggccccgtgatacaagaatcagctgaaccaagccagttggaagttccagccacagaagaa
ataaaagagactgatggaagctctcagatcaagcaagaaccagaccccacgtggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (4)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (58)   
   RefSeq(nuc) (6)   
   GenBank (26)   
   EMBL (26)   
3D Structure (4)   
   PDB (4)   
Protein domain (1)   
   Pfam (1)   
All databases (111)   

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