KEGG   Homo sapiens (human): 2987Help
Entry
2987              CDS       T01001                                 

Gene name
GUK1, GMK
Definition
(RefSeq) guanylate kinase 1
  KO
K00942  guanylate kinase [EC:2.7.4.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa01100  Metabolic pathways
Module
hsa_M00050  Guanine ribonucleotide biosynthesis IMP => GDP,GTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    2987 (GUK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.8  guanylate kinase
     2987 (GUK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Guanylate_kin AAA_33 AAA_18 AAA_16 MMR_HSR1 RsgA_GTPase ABC_tran AAA_22 NACHT cobW AAA_24 AAA_29 AAA_30 AAA_28 dNK DUF2075 NTPase_1 AAA_14 RNA_helicase AAA_17 AAA_5 AAA Zeta_toxin ATPase_2 Dynamin_N Roc Rad17 Viral_helicase1 AAA_23
Motif
Other DBs
NCBI-GeneID: 2987
NCBI-ProteinID: NP_000849
OMIM: 139270
HGNC: 4693
Ensembl: ENSG00000143774
Vega: OTTHUMG00000039503
Pharos: Q16774(Tbio)
UniProt: Q16774 Q6IBG8
Position
1q42.13
AA seq 197 aa AA seqDB search
MSGPRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREV
MQRDIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYI
SVQPPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAE
LKEALSEEIKKAQRTGA
NT seq 594 nt NT seq  +upstreamnt  +downstreamnt
atgtcgggccccaggcctgtggtgctgagcgggccttcgggagctgggaagagcaccctg
ctgaagaggctgctccaggagcacagcggcatctttggcttcagcgtgtcccataccacg
aggaacccgaggcccggcgaggagaacggcaaagattactactttgtaaccagggaggtg
atgcagcgtgacatagcagccggcgacttcatcgagcatgccgagttctcggggaacctg
tatggcacgagcaaggtggcggtgcaggccgtgcaggccatgaaccgcatctgtgtgctg
gacgtggacctgcagggtgtgcggaacatcaaggccaccgatctgcggcccatctacatc
tctgtgcagccgccttcactgcacgtgctggagcagcggctgcggcagcgcaacactgaa
accgaggagagcctggtgaagcggctggctgctgcccaggccgacatggagagcagcaag
gagcccggcctgtttgatgtggtcatcattaacgacagcctggaccaggcctacgcagag
ctgaaggaggcgctctctgaggaaatcaagaaagctcaaaggaccggcgcctga

DBGET integrated database retrieval system