KEGG T01001: 29894

Homo sapiens (human): 29894

Entry

29894 CDS T01001

Gene name

CPSF1, CPSF160, HSU37012, P/cl.18

Definition

cleavage and polyadenylation specific factor 1, 160kDa

Orthology

K14401

cleavage and polyadenylation specificity factor subunit 1

Organism

hsa Homo sapiens (human)

Pathway

hsa03015

mRNA surveillance pathway

Class

Genetic Information Processing; Translation; mRNA surveillance pathway [PATH:hsa03015]

SSDB

Motif

Pfam:

CPSF_A MMS1_N NOA36

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

8q24.23

AA seq 1443 aa
MYAVYKQAHPPTGLEFSMYCNFFNNSERNLVVAGTSQLYVYRLNRDAEALTKNDRSTEGK
AHREKLELAASFSFFGNVMSMASVQLAGAKRDALLLSFKDAKLSVVEYDPGTHDLKTLSL
HYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLVYGTRLVVLPFRRESLAEEHEGLVGEG
QRSSFLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDTCSI
VAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIGGVVVFAVNSLLYLNQSVPPYGVAL
NSLTTGTTAFPLRTQEGVRITLDCAQATFISYDKMVISLKGGEIYVLTLITDGMRSVRAF
HFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEKLQEPPASAVREAADKEEPPSK
KKRVDATAGWSAAGKSVPQDEVDEIEVYGSEAQSGTQLATYSFEVCDSILNIGPCANAAV
GEPAFLSEEFQNSPEPDLEIVVCSGHGKNGALSVLQKSIRPQVVTTFELPGCYDMWTVIA
PVRKEEEDNPKGEGTEQEPSTTPEADDDGRRHGFLILSREDSTMILQTGQEIMELDTSGF
ATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGAPIVQCAVADPYVVIMS
AEGHVTMFLLKSDSYGGRHHRLALHKPPLHHQSKVITLCLYRDLSGMFTTESRLGGARDE
LGGRSGPEAEGLGSETSPTVDDEEEMLYGDSGSLFSPSKEEARRSSQPPADRDPAPFRAE
PTHWCLLVRENGTMEIYQLPDWRLVFLVKNFPVGQRVLVDSSFGQPTTQGEARREEATRQ
GELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKVRFKKVPHNIN
FREKKPKPSKKKAEGGGAEEGAGARGRVARFRYFEDIYGYSGVFICGPSPHWLLVTGRGA
LRLHPMAIDGPVDSFAPFHNVNCPRGFLYFNRQGELRISVLPAYLSYDAPWPVRKIPLRC
TAHYVAYHVESKVYAVATSTNTPCARIPRMTGEEKEFETIERDERYIHPQQEAFSIQLIS
PVSWEAIPNARIELQEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLMQGEEVTCRGRIL
IMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQKIFLWSLRASEL
TGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLVSRDAKPLEVYSVDF
MVDNAQLGFLVSDRDRNLMVYMYLPEAKESFGGMRLLRRADFHVGAHVNTFWRTPCRGAT
EGLSKKSVVWENKHITWFATLDGGIGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPRA
FRMLHVDRRTLQNAVRNVLDGELLNRYLYLSTMERSELAKKIGTTPDIILDDLLETDRVT
AHF

NT seq 4332 nt +upstreamnt +downstreamnt
atgtacgccgtgtacaaacaggcgcatccgcccaccggtctggagttctccatgtactgc
aacttcttcaacaacagcgagcgcaacctggtagtggccgggacctcgcagctctacgtg
taccgcctcaaccgcgacgccgaggctctgaccaagaatgacaggagcacagaggggaag
gcccaccgggagaagctcgagcttgctgcctccttctccttctttggcaacgtcatgtcc
atggccagcgtgcagctggcaggagccaagcgggatgccctgctcctaagcttcaaggat
gccaagctgtctgtggtggagtacgacccgggcacccatgacctgaagaccctgtcactg
cactactttgaggagcctgagcttcgggacgggtttgtgcagaatgtacacacgccgcga
gtgcgggtggaccccgacgggcgctgtgcagccatgcttgtctacggcacgcggctggtg
gtcctgcccttccgcagggagagcctggctgaggagcacgaggggctcgtgggtgagggg
cagaggtccagcttcctgcccagctacatcatcgacgtgcgggccctagacgagaagctg
ctcaacatcatcgacctgcagttcctgcatggctactacgagcctaccctcctcatcctg
tttgagcccaaccagacctggcctgggcgcgtggccgtgcggcaggacacgtgctccatt
gtggccatctcactgaacatcacgcagaaggtgcaccccgtcatctggtccctcaccagc
ctgccctttgactgcacccaggctctggctgtgcccaagcccataggtggggtggtggtg
tttgccgtcaactcgctgttgtacctgaaccagagcgtccccccgtatggcgtggctctc
aacagcctcaccacaggaaccacggctttcccgcttcgcacccaggagggtgtgcggatc
accctggactgcgcccaggccaccttcatctcctacgacaagatggtcatctccctcaag
ggcggcgagatctacgtgctgaccctcatcaccgacggcatgcgcagtgtccgagcgttc
cactttgacaaggcggccgccagcgtcctcaccaccagcatggtcaccatggagcccggg
tacctgttcctgggttctcgcctgggcaattccctcctcctcaagtacacggagaagctg
caggagcccccggccagtgctgtccgtgaggctgccgacaaggaagagcctccctcaaag
aagaagcgagtggatgcgacggccggctggtcagctgcgggtaagtcggtgccgcaggat
gaggtggacgagattgaagtgtacggcagcgaggcccagtcgggaacacagctggccacc
tactcctttgaggtgtgtgacagcatcctgaacattggaccctgtgccaatgccgccgtg
ggcgagcctgccttcctctctgaagagtttcagaacagccccgagccggacctggagatt
gtggtttgctccggccacgggaagaacggggctttgtcggtgctgcagaagagcatccgg
ccccaggtggtgacaacctttgagcttcccggctgctatgacatgtggacagtcatcgcc
ccggtgcgtaaggaggaggaggacaatcccaagggggagggcacagagcaggaacccagc
accacccctgaagcagacgacgacggccgcagacacggattcctgattctgagccgggaa
gactccaccatgatcctgcagacggggcaggagatcatggagctggacaccagtggcttc
gccactcagggccccacggtctttgctgggaacatcggggacaaccgctacattgtccaa
gtgtcaccactgggcatccgcctgctggaaggagtgaatcagctgcacttcatccccgtg
gacctgggcgcccccatcgtgcagtgcgccgtggccgacccctatgtggtcatcatgagt
gccgagggccacgtcaccatgttcctgctgaagagtgactcctacggtggccgccaccac
cgcctggcgctgcacaagcccccgctgcaccatcagtccaaggtgattacgctgtgcctg
taccgagacctcagcggcatgttcaccactgagagccgcctgggtggggcccgtgacgag
ctcgggggccgcagtggcccggaggccgagggcctgggctcagagactagccccacagtg
gatgacgaggaggagatgctgtatggggattcgggctccctcttcagccccagcaaggag
gaggcccgaagaagcagccagccccctgctgaccgggaccctgcacccttccgggcagag
cctacccactggtgcctgctggtgcgggagaatggcaccatggagatctaccagcttccc
gactggcggctggtgttcctggtgaagaacttccctgtggggcagcgggtccttgtggac
agctcctttggacagcccactacacagggcgaggcccgcagggaggaggccacgcgccag
ggggagctgcccctcgtcaaggaggtgctgctggtggcgctgggcagccgccagagcagg
ccctacctgctggtgcatgtggaccaagagctgcttatctacgaggccttcccccacgac
tctcagctcggccagggcaatctcaaagtccgctttaagaaggtccctcacaacatcaac
ttccgtgagaagaagccaaagccatccaagaagaaagcagaaggtggcggcgcagaggag
ggggctggggcccggggccgcgtggcgcgtttccgctacttcgaggatatttatggctac
tcaggggtcttcatctgcggcccctcccctcactggctcttggtgaccggccgaggggct
ctgcggctacaccccatggccatcgacggcccggtcgactctttcgctccattccacaat
gtcaactgtccccgcggcttcctgtacttcaacagacagggcgagctgaggatcagtgtc
ctgcctgcctacctgtcctatgatgccccatggcctgtcaggaagatcccgctgcgctgc
acggcccactatgtggcttaccacgtggagtctaaggtgtatgctgtggccaccagcacc
aacacgccgtgtgcccgcatcccacgcatgactggcgaggagaaggagtttgagaccatc
gagagagatgagcggtacatccacccccagcaggaggccttctccatccagctcatctcc
ccggtcagctgggaggctattcccaatgccaggatcgagctgcaggagtgggagcatgtg
acctgcatgaagacagtgtctctgcgcagtgaggagaccgtgtcgggcctcaaaggctac
gtggccgccgggacctgcctcatgcagggggaggaggtcacgtgccgagggcggatcttg
atcatggatgtgattgaggtggtgcccgagcctggccagcccttgaccaagaacaagttc
aaagtcctttacgagaaggagcagaaggggcccgtgaccgccctgtgccactgcaatggc
cacctggtgtcggccatcggccagaagattttcctgtggagcctgcgggccagcgagctg
acgggcatggccttcatcgacacgcagctctacatacaccagatgatcagcgtcaagaac
ttcatcctggcagccgacgtcatgaagagcatttcgctgctgcgctaccaggaggaaagc
aagacgctgagcctggtgtcgcgggatgccaagcccctggaggtgtacagcgtggacttc
atggtggacaatgcccagctgggttttctggtgtctgaccgcgaccgcaacctcatggtg
tacatgtacctgcccgaagccaaggagagtttcgggggcatgcgcctgctgcgtcgggca
gacttccacgtgggtgcccacgtgaacacgttctggaggaccccgtgccggggggccact
gaagggctcagcaaaaagtcggtcgtgtgggagaataagcacatcacgtggtttgccacc
ctggacggcggcatcgggctgctgctgcccatgcaggagaagacctaccggcggctgctg
atgctgcagaacgcgctgaccaccatgctgccacaccacgccggcctcaacccccgcgcc
ttccggatgctgcacgtggaccgccgcaccctccagaatgccgtgcgcaacgtgctggat
ggggagctgctcaaccgctacctgtacctgagcaccatggagcgcagcgagctagccaag
aagatcggcaccacaccagacataatcctggacgacttgctggagacggaccgcgtcacc
gcccacttctag

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
Protein domain (3)   
   Pfam (3)   
All databases (42)   

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