KEGG T01001: 29958

Homo sapiens (human): 29958

Entry

29958 CDS T01001

Gene name

DMGDH, DMGDHD, ME2GLYDH

Definition

dimethylglycine dehydrogenase (EC:1.5.8.4)

Orthology

K00315

dimethylglycine dehydrogenase [EC:1.5.8.4]

Organism

hsa Homo sapiens (human)

Pathway

hsa00260	Glycine, serine and threonine metabolism
hsa01100	Metabolic pathways

Disease

H01003

Dimethylglycine dehydrogenase deficiency (DMGDHD)

Class

Metabolism; Amino acid metabolism; Glycine, serine and threonine metabolism [PATH:hsa00260]

SSDB

Motif

Pfam:

DAO GCV_T GCV_T_C SoxG Pyr_redox_3 NAD_binding_8 FAD_binding_2 FAD_binding_3 Thi4 Pyr_redox_2 Pyr_redox ApbA NAD_binding_9 Shikimate_DH Lycopene_cycl NAD_binding_7

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

5q14.1

AA seq 866 aa
MLRPGAQLLRGLLLRSCPLQGSPGRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCV
GVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLE
EETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNK
VLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMR
ANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYL
RQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLK
KADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEP
PFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYQRLES
KCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKF
NIKGQDSIRLLDHLFANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSE
LHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTK
SLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRL
EKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATD
DVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPA
VIIQEPLVLTEPTRNRLQKKGGKDKT

NT seq 2601 nt +upstreamnt +downstreamnt
atgctccgtcccggcgcgcagctgctgcggggcctcctgctgcggagctgcccgctgcag
ggctcccccgggcgcccgcgctctgtctgcggccgggaaggagaggaaaaaccaccctta
tctgcagaaacacaatggaaagacagagcagaaacagtgataattggaggtggctgtgtt
ggtgtgagtctggcttatcacctggccaaagcagggatgaaagatgtggtcctgctggag
aaatcagagctcacggctggatctacctggcacgcagcaggtttaacaacttactttcat
cctggaataaacttgaagaaaatacattatgatagcatcaaactttatgagaaactggaa
gaagaaactggtcaggtggtgggattccatcagccaggtagtatcagacttgctaccacc
cctgtaagggtagatgaatttaaatatcaaatgactcggactggctggcatgcaacagaa
cagtatctcattgaacctgaaaaaattcaagagatgttccctttactcaacatgaataag
gttttagctggattgtataatcctggagatggtcacattgatccttattctctaactatg
gcactggctgctggggctaggaaatgtggtgcccttttaaaatatcctgcaccagtaact
tctctgaaagccaggtcagatggaacatgggacgttgaaacaccacaggggtctatgaga
gcaaatagaattgtgaatgctgcaggattttgggctcgtgaagtaggtaaaatgattgga
ctagaacatcctctcattccggttcaacatcaatatgttgttacatcgactatatctgaa
gtgaaagctttgaaacgagaactgcctgtgctccgtgacctggaaggatcatattatctc
cgacaggaaagggatgggcttttgtttggtccatatgaaagtcaagagaaaatgaaagtt
caggactcctgggtcaccaatggagttcctccaggttttggaaaggaactctttgagtct
gatctagatcgaatcatggaacacatcaaagctgccatggaaatggttcctgtcttgaaa
aaggctgacatcatcaatgttgtcaatggtcctatcacgtattctcctgacattctgcct
atggtggggccccatcagggggtcagaaactactgggtggctataggctttggatatggc
ataatccacgctggtggggtagggaaatatctcagtgactggatcctgcatggagaacct
ccttttgatctgatagaattggatcctaatcgctatggcaaatggacaacaacccagtac
actgaggccaaagcaagagaatcatatggattcaacaatattgttggttatcctaaagaa
gaacggtttgctgggaggccgactcaacgagtcagtgggctctatcaaaggctggagtct
aagtgttccatggggttccatgctggctgggagcagccgcactggttctacaaaccaggc
caggacactcagtacaggccaagttttcgccgcacaaactggtttgagcctgtgggctcg
gagtataaacaggttatgcaaagagtagcggtaactgacctatcaccatttggcaagttt
aacatcaaaggccaagattccattagactactggaccatctctttgcaaatgtcattcca
aaggtgggttttacaaatataagtcacatgttaacacccaagggtcgagtgtatgctgag
ctgactgtttctcaccaatctcctggggagtttcttttaattactggctctggatcagaa
cttcatgatcttagatggattgaagaagaagcagtcaaaggtggatatgatgttgaaatt
aaaaacataactgatgagcttggagttcttggagttgctgggccacaggcaagaaaggtc
cttcagaaactgacctctgaagatcttagtgatgatgttttcaagtttcttcaaaccaag
tccttaaaggtttccaacattcctgtcactgctattaggatatcttatactggtgagctg
ggttgggagctgtatcacagaagagaagattctgtggcgctgtatgacgctatcatgaat
gcaggccaggaggagggaatcgacaattttggaacctatgccatgaatgccttacgcctg
gagaaagccttcagagcctgggggttagagatgaactgtgatacaaatcctttggaagct
ggactggaatattttgtgaagttaaataagccagcagacttcataggaaagcaagcactg
aaacagattaaagccaaggggctgaaacgaagactggtctgcctcaccttggcaacggat
gatgttgatccagagggaaatgaaagcatctggtacaatggcaaggtggttggcaacacg
acatctggaagctatagctacagcatccagaagagtctggctttcgcatatgtccctgta
caactaagtgaagtgggacagcaagtggaagttgaactattaggcaaaaattacccagca
gtcatcatacaagaacctttggtattgaccgaaccaaccagaaaccggcttcagaaaaaa
ggtggaaaggacaaaacttga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
Protein domain (16)   
   Pfam (16)   
All databases (70)   

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