KEGG T01001: 3059

Homo sapiens (human): 3059

Entry

3059 CDS T01001

Gene name

HCLS1, CTTNL, HS1

Definition

hematopoietic cell-specific Lyn substrate 1

Orthology

K06106

cortactin

Organism

hsa Homo sapiens (human)

Pathway

hsa04530	Tight junction
hsa05100	Bacterial invasion of epithelial cells
hsa05130	Pathogenic Escherichia coli infection
hsa05131	Shigellosis
hsa05205	Proteoglycans in cancer

Class

Cellular Processes; Cell communication; Tight junction [PATH:hsa04530]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:hsa05205]
Human Diseases; Infectious diseases; Pathogenic Escherichia coli infection [PATH:hsa05130]
Human Diseases; Infectious diseases; Shigellosis [PATH:hsa05131]
Human Diseases; Infectious diseases; Bacterial invasion of epithelial cells [PATH:hsa05100]

SSDB

Motif

Pfam:

HS1_rep SH3_1 SH3_9 SH3_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

3q13

AA seq 486 aa
MWKSVVGHDVSVSVETQGDDWDTDPDFVNDISEKEQRWGAKTIEGSGRTEHINIHQLRNK
VSEEHDVLRKKEMESGPKASHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKGF
GGKYGVERDRADKSAVGFDYKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDYKGE
TEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFNEMEAPTTAYKKTTPIEAASSGTRGLKA
KFESMAEEKRKREEEEKAQQVARRQQERKAVTKRSPEAPQPVIAMEEPAVPAPLPKKISS
EAWPPVGTPPSSESEPVRTSREHPVPLLPIRQTLPEDNEEPPALPPRTLEGLQVEEEPVY
EAEPEPEPEPEPEPENDYEDVEEMDRHEQEDEPEGDYEEVLEPEDSSFSSALAGSSGCPA
GAGAGAVALGISAVALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHGHFGLFPAN
YVKLLE

NT seq 1461 nt +upstreamnt +downstreamnt
atgtggaagtctgtagtgggccatgatgtgtctgtttccgtggagacccagggtgatgat
tgggacacagatcctgactttgtgaatgacatctctgaaaaggagcaacgatggggagcc
aagaccatcgaggggtctggacgcacagaacacatcaacatccaccagctgaggaacaaa
gtatcagaggagcatgatgttctcaggaagaaagagatggagtcagggcccaaagcatcc
catggctatggaggtcggtttggagtagaaagagaccgaatggacaagagtgcagtgggc
catgagtatgttgccgaggtggagaagcactcttctcagacggatgctgccaaaggcttt
gggggcaagtacggagttgagagggacagggcagacaagtcagcagtcggctttgattat
aaaggagaagtggagaagcacacatctcagaaagattactctcgtggctttggtggccgg
tacggggtggagaaggataaatgggacaaagcagctctgggatatgactacaagggagag
acggagaaacacgagtcccagagagattatgccaagggctttggtggccagtatggaatc
cagaaggaccgagtggataagagcgctgtcggcttcaatgaaatggaggccccgaccaca
gcttataagaagacgacgcccatagaagccgcttctagtggtacccgtgggctgaaggcg
aaatttgagtccatggctgaggagaagaggaagcgagaggaagaggagaaggcacagcag
gtggccaggaggcaacaggagcgaaaggctgtgacaaagaggagccctgaggctccacag
ccagtgatagctatggaagagccagcagtaccggccccactgcccaagaaaatctcctca
gaggcctggcctccagttgggactcctccatcatcagagtctgagcctgtgagaaccagc
agggaacacccagtgcccttgctgcccattaggcagactctcccggaggacaatgaggag
cccccagctctgccccctaggactctggaaggcctccaggtggaggaagagccagtgtac
gaagcagagcctgagcctgagcccgagcctgagcccgagcctgagaatgactatgaggac
gttgaggagatggacaggcatgagcaggaggatgaaccagagggggactatgaggaggtg
ctcgagcctgaagattcttctttttcttctgctctggctggatcatcaggctgcccggct
ggggctggggctggggctgtggctctggggatctcagctgtggctctatatgattaccaa
ggagagggaagtgatgagctttcctttgatccggacgacgtaatcactgacattgagatg
gtggacgagggctggtggcggggacgttgccatggccactttggactcttccctgcaaat
tatgtcaagcttctggagtga

All links

Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (11)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (29)   
   RefSeq(nuc) (1)   
   GenBank (14)   
   EMBL (14)   
Protein domain (4)   
   Pfam (4)   
All databases (61)   

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