KEGG   Homo sapiens (human): 30837Help
Entry
30837             CDS       T01001                                 

Gene name
SOCS7, NAP4, NCKAP4
Definition
(RefSeq) suppressor of cytokine signaling 7
  KO
K04699  suppressor of cytokine signaling 6/7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04630  Jak-STAT signaling pathway
hsa04917  Prolactin signaling pathway
Module
hsa_M00388  ECS complex
hsa_M00684  JAK-STAT signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    30837 (SOCS7)
 Organismal Systems
  Endocrine system
   04917 Prolactin signaling pathway
    30837 (SOCS7)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   ECS complex
    Target recognizing subunit (SOCS box)
     30837 (SOCS7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SOCS_box SH2
Motif
Other DBs
NCBI-GeneID: 30837
NCBI-ProteinID: NP_055413
OMIM: 608788
HGNC: 29846
Ensembl: ENSG00000274211
Vega: OTTHUMG00000188546
Pharos: O14512(Tbio)
UniProt: O14512
Position
17q12
AA seq 581 aa AA seqDB search
MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQL
AALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGL
ESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ
QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGE
LAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGL
TSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA
PIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDG
SFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIM
HSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPL
PKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST
NT seq 1746 nt NT seq  +upstreamnt  +downstreamnt
atggtgttccgcaacgtgggtcggccgccggaggaggaggacgtggaggcggccccggag
ccgggaccctcggaactgctgtgtccccggcaccgctgtgccctggaccccaaggccctg
ccgccgggcttggcgctcgagcggacctggggcccggcggctggactagaggcgcagttg
gcggctctggggctcgggcagccggcggggccgggggtcaagacagtcggtgggggttgc
tgcccgtgtccgtgtcctcctcagccgccccctccgcagccccagccgcctgctgccgcc
ccgcaggccggggaggaccccacggaaacgagcgacgcgctgctggtcctggagggcttg
gaatcggaggccgagagcctggagactaacagctgctcggaagaggagctcagcagcccg
ggtcgcggaggaggagggggcggccggcttctgctgcagcccccaggccctgaattacct
ccggtgcccttcccgctgcaggacttggtccctctggggcgcctgagtagaggggagcag
cagcagcagcagcagcagcaacctcccccgcccccgcctcctcccgggcccctccggcca
ctcgcgggtccttctcggaagggctccttcaaaatccgcctcagtcgcctctttcgcacc
aagagctgcaacggtggctccggcggtggggatgggaccggcaagaggccttctggagag
ctggctgcttcagctgcgagcctgacagacatgggaggctctgcgggccgggagctggac
gcggggaggaaacccaagttgacaagaactcaaagtgccttttctccggtctccttcagc
cccctgttcacaggtgaaactgtgtcgcttgtggatgtggacatttctcagcggggcctg
acctctccacaccctccaactccccctcctcctccgagaagaagcctcagcctcctagat
gatatcagtgggacgctgcctacatctgtccttgtggctccgatggggtcttccttgcag
tctttccccctacctccgcctcctccaccccatgccccagatgcatttccccggattgct
cccatccgagcagctgaatccctgcacagccaacccccacagcacctccagtgtcccctc
taccggcctgactcgagcagctttgcagccagccttcgagagttggagaagtgtggttgg
tattgggggccaatgaattgggaagatgcagagatgaagctgaaagggaaaccagatggt
tctttcctggtacgagacagttctgatcctcgttacatcctgagcctcagtttccgatca
cagggtatcacccaccacactagaatggagcactacagaggaaccttcagcctgtggtgt
catcccaagtttgaggaccgctgtcaatctgttgtagagtttattaagagagccattatg
cactccaagaatggaaagtttctctatttcttaagatccagggttccaggactgccacca
actcctgtccagctgctctatccagtgtcccgattcagcaatgtcaaatccctccagcac
ctttgcagattccggatacgacagctcgtcaggatagatcacatcccagatctcccactg
cctaaacctctgatctcttatatccgaaagttctactactatgatcctcaggaagaggta
tacctgtctctaaaggaagcgcagctcatttccaaacagaagcaagaggtggaaccctcc
acgtag

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