| Entry |
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| Gene name |
IARS, IARS1, ILERS, ILRS, IRS, PRO0785
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| Definition |
isoleucyl-tRNA synthetase (EC:6.1.1.5)
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| Orthology |
| isoleucyl-tRNA synthetase [EC: 6.1.1.5] |
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| Organism |
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| Pathway |
| Aminoacyl-tRNA biosynthesis |
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| Module |
| Aminoacyl-tRNA biosynthesis, eukaryotes |
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| Class |
Genetic Information Processing; Translation; Aminoacyl-tRNA biosynthesis [PATH: hsa00970]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Position |
9q21
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| AA seq |
1262 aa  
MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHIL
AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQC
RAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMP
FSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNP
EMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFDYFLKCK
ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTT
EVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVE
NMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVC
IGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHY
PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQK
MSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY
RFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV
PRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELM
YQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKT
IPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMV
LGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQ
FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGT
YLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSSLPGPAC
AYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQN
QTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPL
GQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTA
DF |
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| NT seq |
3789 nt  +upstreamnt +downstreamnt
atgcttcaacaagttccagaaaacataaattttcctgctgaagaagagaaaatcttggag
ttttggactgaatttaattgttttcaggaatgcttaaagcaatcaaaacataaaccaaaa
tttaccttctatgatggtcctccttttgcaactggactgcctcactatggacatatactt
gcgggtacaattaaagatatagttacaagatatgctcaccagagtgggtttcatgttgac
agaagatttggatgggattgccatggcttacctgtggaatatgaaattgataagacactg
ggaatcagaggaccagaggatgtggccaaaatggggattacagagtataacaatcagtgc
cgagcaattgtgatgagatattctgctgagtggaagtctactgttagcagacttggccga
tggattgactttgacaatgactataaaactctgtatccacaattcatggaatcagtctgg
tgggtcttcaaacaactctatgataaaggccttgtttatagaggtgtgaaagtcatgccc
ttctctacggcatgtaacactccactttccaacttcgagtcacaccagaattataaggat
gttcaagatccttcagtatttgtaactttccctttggaagaagatgaaactgtatcttta
gttgcttggacaaccactccctggactctacctagtaaccttgctgtgtgtgttaatcca
gaaatgcaatatgtgaaaattaaagatgttgccagaggacgattactcattttaatggaa
gccagattgtcagccctctataaattggagagtgactatgagatccttgaaagatttcct
ggtgcctatcttaaaggcaagaagtacaggcccctgtttgactatttcctgaagtgtaaa
gagaatggcgctttcactgtgcttgttgacaactatgtgaaggaagaagaaggcacaggg
gttgtccaccaagctccttacttcggtgctgaggactatcgggtctgtatggactttaac
attattcggaaagactcactccctgtttgccctgtggatgcttcaggctgcttcacaacg
gaggtgacagatttcgcaggacagtatgtgaaggatgctgacaaaagtatcatcaggact
ttgaaggaacaaggccgacttctggttgccaccaccttcactcacagctaccctttttgc
tggagatcagacactcctctaatttacaaagcagtgcccagctggtttgtgcgagtggag
aacatggtggaccagctcctaaggaacaatgacctgtgctactgggtcccagagttggta
cgagaaaaacgatttggaaattggctgaaagatgcacgtgactggacaatttccagaaac
agatactggggcacccccatcccactgtgggtcagcgatgactttgaggaggtggtatgc
attgggtcagtggcggaacttgaagaactgtcaggagcaaagatctcagatctccacaga
gagagtgttgaccacctgaccattccttcacgctgtgggaagggatccttgcaccgcatc
tctgaagtgtttgactgttggtttgagagtggcagcatgccctatgctcaggttcattac
ccgtttgaaaacaagagggagtttgaggatgcttttcctgcagatttcattgccgagggc
atcgaccaaaccagaggatggttttataccctgctggtgctggccacggccctctttgga
caaccgcctttcaagaacgtaattgtgaatgggcttgtcctggcaagtgatggccaaaaa
atgagcaaacggaaaaagaattatccagatccagtttccatcatccagaagtatggtgct
gatgccctcagattatatctgattaactcccctgtggtgagagcagaaaacctccgcttt
aaagaagagggtgtgcgggacgtccttaaggatgtactgctcccatggtacaatgcctat
cgcttcttaatccagaacgttctgaggctccagaaggaggaagaaatagaatttctctac
aatgagaacacggttagagaaagccccaacattacagaccggtggatcctgtccttcatg
cagtctctcattggcttctttgagactgaaatggcagcttataggctttatactgtggtg
cctcgcctggtcaagtttgtagatattctgaccaattggtatgttagaatgaaccgcaga
agattaaagggtgaaaatgggatggaggattgtgtcatggccctagaaaccttgtttagt
gttctgctttctctttgcagacttatggctccctacacaccttttctcactgaattgatg
taccagaatctaaaggtgctgattgaccctgtttctgttcaggacaaggacacactcagc
attcactacctcatgctgccccgtgttcgagaagaattgattgacaagaaaacagagagt
gcagtatctcagatgcagtctgtgattgaacttggaagagtgatcagagaccgaaaaact
attcccataaagtatcctttgaaagaaattgtggttatccatcaagatccagaagctctt
aaagatatcaagtctttggagaagtatatcattgaggaactcaatgttcgaaaagttaca
ctgtctacagataaaaacaagtatggcattcggctaagggcagaaccagatcacatggtc
ctggggaagcgtctgaagggagcctttaaggcagtgatgacgtccatcaagcagttgagc
agtgaggagctggagcagttccagaagactgggaccattgttgtggaaggccatgaattg
cacgatgaagacatccgcctcatgtacacctttgatcaggccacaggtgggactgcgcaa
tttgaagcacactcagatgctcaggctttggtcctcttagatgtcactcctgaccagtca
atggtagatgaaggaatggctcgggaagtcatcaatcgcatacagaaacttcgcaaaaag
tgcaatctggttccaactgatgaaatcacagtgtactataaagcaaagtctgaaggaaca
tatctgaatagtgttattgaaagccacacagagttcatatttaccaccataaaggctccc
ttgaaaccatatccagtttctccatcggataaagtccttattcaagaaaaaacacagttg
aagggatctgaactggaaattacactcaccagaggatcttcccttcctggtcctgcttgt
gcatatgtcaatcttaacatttgtgcaaatggcagtgaacaaggtggagtattgctcctg
gaaaatccaaaaggtgacaataggttggaccttttaaagctgaagagtgttgtcactagc
atttttggtgtgaaaaatacagagctggctgtcttccatgatgaaacagaaatacaaaac
caaactgacttactgagtcttagtggaaaaacactttgtgtgactgcaggatcggctccc
tctctgatcaacagttctagtactcttctttgtcagtatatcaacctacagctcctgaat
gcaaagccacaagagtgtttaatggggacagtgggcactctcctgcttgaaaacccactt
gggcagaatggactcacccaccaaggtcttctgtatgaagcagccaaggtgtttggcctt
cggagcaggaagctaaagctgtttctgaatgagacccaaacgcaggaaattacagaagac
atccccgtgaagactttgaatatgaagactgtgtatgtttctgtgttaccaacaacagca
gacttctag |
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