| Entry |
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| Gene name |
ACADM, ACAD1, MCAD, MCADH
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| Definition |
acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7)
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| Orthology |
| acyl-CoA dehydrogenase [EC: 1.3.8.7] |
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| Organism |
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| Pathway |
| Fatty acid metabolism | | Valine, leucine and isoleucine degradation | | beta-Alanine metabolism | | Propanoate metabolism | | Metabolic pathways | | PPAR signaling pathway |
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| Module |
| Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA | | Leucine degradation, leucine => acetoacetate + acetyl-CoA | | beta-Oxidation |
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| Disease |
| Disorders of fatty-acid oxidation |
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| Class |
Metabolism; Carbohydrate metabolism; Propanoate metabolism [PATH: hsa00640]
Metabolism; Lipid metabolism; Fatty acid metabolism [PATH: hsa00071]
Metabolism; Amino acid metabolism; Valine, leucine and isoleucine degradation [PATH: hsa00280]
Metabolism; Metabolism of other amino acids; beta-Alanine metabolism [PATH: hsa00410]
Organismal Systems; Endocrine system; PPAR signaling pathway [PATH: hsa03320]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Structure |
PDB: |
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| Position |
1p31
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| AA seq |
421 aa  
MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEI
IPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQ
TAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKG
DEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNM
GQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEAT
KYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAF
AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK
N |
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| NT seq |
1266 nt  +upstreamnt +downstreamnt
atggcagcggggttcgggcgatgctgcagggtcctgagaagtatttctcgttttcattgg
agatcacagcatacaaaagccaatcgacaacgtgaaccaggattaggatttagttttgag
ttcaccgaacagcagaaagaatttcaagctactgctcgtaaatttgccagagaggaaatc
atcccagtggctgcagaatatgataaaactggtgaatatccagtccccctaattagaaga
gcctgggaacttggtttaatgaacacacacattccagagaactgtggaggtcttggactt
ggaacttttgatgcttgtttaattagtgaagaattggcttatggatgtacaggggttcag
actgctattgaaggaaattctttggggcaaatgcctattattattgctggaaatgatcaa
caaaagaagaagtatttggggagaatgactgaggagccattgatgtgtgcttattgtgta
acagaacctggagcaggctctgatgtagctggtataaagaccaaagcagaaaagaaagga
gatgagtatattattaatggtcagaagatgtggataaccaacggaggaaaagctaattgg
tattttttattggcacgttctgatccagatcctaaagctcctgctaataaagcctttact
ggattcattgtggaagcagataccccaggaattcagattgggagaaaggaattaaacatg
ggccagcgatgttcagatactagaggaattgtcttcgaagatgtgaaagtgcctaaagaa
aatgttttaattggtgacggagctggtttcaaagttgcaatgggagcttttgataaaacc
agacctgtagtagctgctggtgctgttggattagcacaaagagctttggatgaagctacc
aagtatgccctggaaaggaaaactttcggaaagctacttgtagagcaccaagcaatatca
tttatgctggctgaaatggcaatgaaagttgaactagctagaatgagttaccagagagca
gcttgggaggttgattctggtcgtcgaaatacctattatgcttctattgcaaaggcattt
gctggagatattgcaaatcagttagctactgatgctgtgcagatacttggaggcaatgga
tttaatacagaatatcctgtagaaaaactaatgagggatgccaaaatctatcagatttat
gaaggtacttcacaaattcaaagacttattgtagcccgtgaacacattgacaagtacaaa
aattaa |
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