| Entry |
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| Gene name |
IFNA14, IFN-alphaH, LEIF2H
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| Definition |
(RefSeq) interferon alpha 14
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| KO |
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| Organism |
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| Pathway |
| Cytokine-cytokine receptor interaction | | PI3K-Akt signaling pathway | | Necroptosis | | Toll-like receptor signaling pathway | | NOD-like receptor signaling pathway | | RIG-I-like receptor signaling pathway | | Cytosolic DNA-sensing pathway | | Jak-STAT signaling pathway | | Natural killer cell mediated cytotoxicity | | Tuberculosis | | Hepatitis C | | Hepatitis B | | Measles | | Influenza A | | Human papillomavirus infection | | Kaposi's sarcoma-associated herpesvirus infection | | Herpes simplex infection | | Pathways in cancer | | Autoimmune thyroid disease |
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| Network |
| TLR3-IRF7 signaling pathway | | Type I IFN signaling pathway | | KSHV vIRF3 to TLR3-IRF7 signaling pathway | | KSHV KIE1/2 to TLR3-IRF7 signaling pathway |
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| Drug target |
Rontalizumab: Sifalimumab: |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
Environmental Information Processing
Signal transduction
04630 Jak-STAT signaling pathway
3448 (IFNA14)
04151 PI3K-Akt signaling pathway
3448 (IFNA14)
Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
3448 (IFNA14)
Cellular Processes
Cell growth and death
04217 Necroptosis
3448 (IFNA14)
Organismal Systems
Immune system
04620 Toll-like receptor signaling pathway
3448 (IFNA14)
04621 NOD-like receptor signaling pathway
3448 (IFNA14)
04622 RIG-I-like receptor signaling pathway
3448 (IFNA14)
04623 Cytosolic DNA-sensing pathway
3448 (IFNA14)
04650 Natural killer cell mediated cytotoxicity
3448 (IFNA14)
Human Diseases
Cancers
05200 Pathways in cancer
3448 (IFNA14)
Immune diseases
05320 Autoimmune thyroid disease
3448 (IFNA14)
Infectious diseases
05152 Tuberculosis
3448 (IFNA14)
05162 Measles
3448 (IFNA14)
05164 Influenza A
3448 (IFNA14)
05161 Hepatitis B
3448 (IFNA14)
05160 Hepatitis C
3448 (IFNA14)
05168 Herpes simplex infection
3448 (IFNA14)
05167 Kaposi's sarcoma-associated herpesvirus infection
3448 (IFNA14)
05165 Human papillomavirus infection
3448 (IFNA14)
Cytokines [BR:hsa04052]
Class II cytokines (interferon/IL-10 family)
Type I interferons
3448 (IFNA14)
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GeneID: NCBI-ProteinID: OMIM: HGNC: Ensembl: Vega: Pharos: UniProt: |
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| Position |
9p21.3
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| AA seq |
189 aa  
MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
LQKRLRRKD |
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| NT seq |
570 nt  +upstreamnt +downstreamnt
atggcattgccctttgctttaatgatggccctggtggtgctcagctgcaagtcaagctgc
tctctgggctgtaatctgtctcaaacccacagcctgaataacaggaggactttgatgctc
atggcacaaatgaggagaatctctcctttctcctgcctgaaggacagacatgactttgaa
tttccccaggaggaatttgatggcaaccagttccagaaagctcaagccatctctgtcctc
catgagatgatgcagcagaccttcaatctcttcagcacaaagaactcatctgctgcttgg
gatgagaccctcctagaaaaattctacattgaacttttccagcaaatgaatgacctggaa
gcctgtgtgatacaggaggttggggtggaagagactcccctgatgaatgaggactccatc
ctggctgtgaagaaatacttccaaagaatcactctttatctgatggagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccctctctttttcaacaaac
ttgcaaaaaagattaaggaggaaggattga |
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