KEGG   Homo sapiens (human): 3452Help
Entry
3452              CDS       T01001                                 

Gene name
IFNA21, IFN-alphaI, LeIF_F, leIF-F
Definition
(RefSeq) interferon alpha 21
  KO
K05414  interferon alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04217  Necroptosis
hsa04620  Toll-like receptor signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa04623  Cytosolic DNA-sensing pathway
hsa04630  Jak-STAT signaling pathway
hsa04650  Natural killer cell mediated cytotoxicity
hsa05152  Tuberculosis
hsa05160  Hepatitis C
hsa05161  Hepatitis B
hsa05162  Measles
hsa05164  Influenza A
hsa05165  Human papillomavirus infection
hsa05167  Kaposi's sarcoma-associated herpesvirus infection
hsa05168  Herpes simplex infection
hsa05200  Pathways in cancer
hsa05320  Autoimmune thyroid disease
Network
N00148  TLR3-IRF7 signaling pathway
N00150  Type I IFN signaling pathway
N00162  KSHV vIRF3 to TLR3-IRF7 signaling pathway
N00163  KSHV KIE1/2 to TLR3-IRF7 signaling pathway
Drug target
Rontalizumab: D09662
Sifalimumab: D09668
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    3452 (IFNA21)
   04151 PI3K-Akt signaling pathway
    3452 (IFNA21)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    3452 (IFNA21)
 Cellular Processes
  Cell growth and death
   04217 Necroptosis
    3452 (IFNA21)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    3452 (IFNA21)
   04621 NOD-like receptor signaling pathway
    3452 (IFNA21)
   04622 RIG-I-like receptor signaling pathway
    3452 (IFNA21)
   04623 Cytosolic DNA-sensing pathway
    3452 (IFNA21)
   04650 Natural killer cell mediated cytotoxicity
    3452 (IFNA21)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    3452 (IFNA21)
  Immune diseases
   05320 Autoimmune thyroid disease
    3452 (IFNA21)
  Infectious diseases
   05152 Tuberculosis
    3452 (IFNA21)
   05162 Measles
    3452 (IFNA21)
   05164 Influenza A
    3452 (IFNA21)
   05161 Hepatitis B
    3452 (IFNA21)
   05160 Hepatitis C
    3452 (IFNA21)
   05168 Herpes simplex infection
    3452 (IFNA21)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    3452 (IFNA21)
   05165 Human papillomavirus infection
    3452 (IFNA21)
Cytokines and growth factors [BR:hsa04052]
 Cytokines
  Interferons
   3452 (IFNA21)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Interferon
Motif
Other DBs
NCBI-GeneID: 3452
NCBI-ProteinID: NP_002166
OMIM: 147584
HGNC: 5424
Ensembl: ENSG00000137080
Vega: OTTHUMG00000019653
Pharos: P01568(Tbio)
UniProt: P01568
Position
9p21.3
AA seq 189 aa AA seqDB search
MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
FQERLRRKE
NT seq 570 nt NT seq  +upstreamnt  +downstreamnt
atggccctgtccttttctttactgatggccgtgctggtgctcagctacaaatccatctgt
tctctgggctgtgatctgcctcagacccacagcctgggtaataggagggccttgatactc
ctggcacaaatgggaagaatctctcctttctcctgcctgaaggacagacatgactttgga
ttcccccaggaggagtttgatggcaaccagttccagaaggctcaagccatctctgtcctc
catgagatgatccagcagaccttcaatctcttcagcacaaaggactcatctgctacttgg
gaacagagcctcctagaaaaattttccactgaacttaaccagcagctgaatgacctggaa
gcctgcgtgatacaggaggttggggtggaagagactcccctgatgaatgtggactccatc
ctggctgtgaagaaatacttccaaagaatcactctttatctgacagagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccttctctttatcaaaaatt
tttcaagaaagattaaggaggaaggaatga

DBGET integrated database retrieval system