KEGG T01001: 3482

Homo sapiens (human): 3482

Entry

3482 CDS T01001

Gene name

IGF2R, CD222, CIMPR, M6P-R, MPR1, MPRI

Definition

insulin-like growth factor 2 receptor

Orthology

K06564

insulin-like growth factor 2 receptor

Organism

hsa Homo sapiens (human)

Pathway

hsa04142

Lysosome

Disease

H00048

Hepatocellular carcinoma

Class

Cellular Processes; Transport and catabolism; Lysosome [PATH:hsa04142]

SSDB

Motif

Pfam:

CIMR fn2 DUF3792

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1E6F 1GP3 2V5O 2V5N 2V5P 2L29 2L2A 2CNJ 1GQB 1GP0

Position

6q26

AA seq 2491 aa
MGAAAGRSPHLGPAPARRPQRSLLLLQLLLLVAAPGSTQAQAAPFPELCSYTWEAVDTKN
NVLYKINICGSVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLRSATRSLLEFNTTVSCDQQ
GTNHRVQSSIAFLCGKTLGTPEFVTATECVHYFEWRTTAACKKDIFKANKEVPCYVFDEE
LRKHDLNPLIKLSGAYLVDDSDPDTSLFINVCRDIDTLRDPGSQLRACPPGTAACLVRGH
QAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCDGHSPAVTITFVCPSERREGTIPKL
TAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGSSYISDGKEYL
FYLNVCGETEIQFCNKKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDEC
SSGFQRMSVINFECNKTAGNDGKGTPVFTGEVDCTYFFTWDTEYACVKEKEDLLCGATDG
KKRYDLSALVRHAEPEQNWEAVDGSQTETEKKHFFINICHRVLQEGKARGCPEDAAVCAV
DKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTS
GEGGCFYEFEWHTAAACVLSKTEGENCTVFDSQAGFSFDLSPLTKKNGAYKVETKKYDFY
INVCGPVSVSPCQPDSGACQVAKSDEKTWNLGLSNAKLSYYDGMIQLNYRGGTPYNNERH
TPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECVVTDPSTLEQYDL
SSLAKSEGGLGGNWYAMDNSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGS
FTEVVSISNLGMAKTGPVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNS
HPIFSLNWECVVSFLWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSG
IGKIFMFNVCGTMPVCGTILGKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFIT
LTYKGPLSAKGTADAFIVRFVCNDDVYSGPLKFLHQDIDSGQGIRNTYFEFETALACVPS
PVDCQVTDLAGNEYDLTGLSTVRKPWTAVDTSVDGRKRTFYLSVCNPLPYIPGCQGSAVG
SCLVSEGNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFECAQISGSPAFQ
LQDGCEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFR
VCGKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCH
KVYQRSTAIFFYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDLTECSFKDGAGNSFD
LSSLSRYSDNWEAITGTGDPEHYLINVCKSLAPQAGTEPCPPEAAACLLGGSKPVNLGRV
RDGPQWRDGIIVLKYVDGDLCPDGIRKKSTTIRFTCSESQVNSRPMFISAVEDCEYTFAW
PTATACPMKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCP
PGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEAGP
TNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIHRTGGYEAYDESE
DDASDTNPDFYINICQPLNPMHGVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEI
YLNFESSTPCLADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCPDEVR
MDGCTLTDEQLLYSFNLSSLSTSTFKVTRDSRTYSVGVCTFAVGPEQGGCKDGGVCLLSG
TKGASFGRLQSMKLDYRHQDEAVVLSYVNGDRCPPETDDGVPCVFPFIFNGKSYEECIIE
SRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCDEDEDIGRPQVFSEVRGCDVTFE
WKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWSLVHNGVSYYINLCQKIYKGPLGCS
ERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVVTYSKGYPCGGNKTASSVIELTCTKTV
GRPAFKRFDIDSCTYYFSWDSRAACAVKPQEVQMVNGTITNPINGKSFSLGDIYFKLFRA
SGDMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDQHFSRKVGTSDKTKYYLQDG
DLDVVFASSSKCGKDKTKSVSSTIFFHCDPLVEDGIPEFSHETADCQYLFSWYTSAVCPL
GVGFDSENPGDDGQMHKGLSERSQAVGAVLSLLLVALTCCLLALLLYKKERRETVISKLT
TCCRRSSNVSYKYSKVNKEEETDENETEWLMEEIQLPPPRQGKEGQENGHITTKSVKALS
SLHGDDQDSEDEVLTIPEVKVHSGRGAGAESSHPVRNAQSNALQEREDDRVGLVRGEKAR
KGKSSSAQQKTVSSTKLVSFHDDSDEDLLHI

NT seq 7476 nt +upstreamnt +downstreamnt
atgggggccgccgccggccggagcccccacctggggcccgcgcccgcccgccgcccgcag
cgctctctgctcctgctgcagctgctgctgctcgtcgctgccccggggtccacgcaggcc
caggccgccccgttccccgagctgtgcagttatacatgggaagctgttgataccaaaaat
aatgtactttataaaatcaacatctgtggaagtgtggatattgtccagtgcgggccatca
agtgctgtttgtatgcacgacttgaagacacgcacttatcattcagtgggtgactctgtt
ttgagaagtgcaaccagatctctcctggaattcaacacaacagtgagctgtgaccagcaa
ggcacaaatcacagagtccagagcagcattgccttcctgtgtgggaaaaccctgggaact
cctgaatttgtaactgcaacagaatgtgtgcactactttgagtggaggaccactgcagcc
tgcaagaaagacatatttaaagcaaataaggaggtgccatgctatgtgtttgatgaagag
ttgaggaagcatgatctcaatcctctgatcaagcttagtggtgcctacttggtggatgac
tccgatccggacacttctctattcatcaatgtttgtagagacatagacacactacgagac
ccaggttcacagctgcgggcctgtccccccggcactgccgcctgcctggtaagaggacac
caggcgtttgatgttggccagccccgggacggactgaagctggtgcgcaaggacaggctt
gtcctgagttacgtgagggaagaggcaggaaagctagacttttgtgatggtcacagccct
gcggtgactattacatttgtttgcccgtcggagcggagagagggcaccattcccaaactc
acagctaaatccaactgccgctatgaaattgagtggattactgagtatgcctgccacaga
gattacctggaaagtaaaacttgttctctgagcggcgagcagcaggatgtctccatagac
ctcacaccacttgcccagagcggaggttcatcctatatttcagatggaaaagaatatttg
ttttatttgaatgtctgtggagaaactgaaatacagttctgtaataaaaaacaagctgca
gtttgccaagtgaaaaagagcgatacctctcaagtcaaagcagcaggaagataccacaat
cagaccctccgatattcggatggagacctcaccttgatatattttggaggtgatgaatgc
agctcagggtttcagcggatgagcgtcataaactttgagtgcaataaaaccgcaggtaac
gatgggaaaggaactcctgtattcacaggggaggttgactgcacctacttcttcacatgg
gacacggaatacgcctgtgttaaggagaaggaagacctcctctgcggtgccaccgacggg
aagaagcgctatgacctgtccgcgctggtccgccatgcagaaccagagcagaattgggaa
gctgtggatggcagtcagacggaaacagagaagaagcattttttcattaatatttgtcac
agagtgctgcaggaaggcaaggcacgagggtgtcccgaggacgcggcagtgtgtgcagtg
gataaaaatggaagtaaaaatctgggaaaatttatttcctctcccatgaaagagaaagga
aacattcaactctcttattcagatggtgatgattgtggtcatggcaagaaaattaaaact
aatatcacacttgtatgcaagccaggtgatctggaaagtgcaccagtgttgagaacttct
ggggaaggcggttgcttttatgagtttgagtggcacacagctgcggcctgtgtgctgtct
aagacagaaggggagaactgcacggtctttgactcccaggcagggttttcttttgactta
tcacctctcacaaagaaaaatggtgcctataaagttgagacaaagaagtatgacttttat
ataaatgtgtgtggcccggtgtctgtgagcccctgtcagccagactcaggagcctgccag
gtggcaaaaagtgatgagaagacttggaacttgggtctgagtaatgcgaagctttcatat
tatgatgggatgatccaactgaactacagaggcggcacaccctataacaatgaaagacac
acaccgagagctacgctcatcacctttctctgtgatcgagacgcgggagtgggcttccct
gaatatcaggaagaggataactccacctacaacttccggtggtacaccagctatgcctgc
ccggaggagcccctggaatgcgtagtgaccgacccctccacgctggagcagtacgacctc
tccagtctggcaaaatctgaaggtggccttggaggaaactggtatgccatggacaactca
ggggaacatgtcacgtggaggaaatactacattaacgtgtgtcggcctctgaatccagtg
ccgggctgcaaccgatatgcatcggcttgccagatgaagtatgaaaaagatcagggctcc
ttcactgaagtggtttccatcagtaacttgggaatggcaaagaccggcccggtggttgag
gacagcggcagcctccttctggaatacgtgaatgggtcggcctgcaccaccagcgatggc
agacagaccacatataccacgaggatccatctcgtctgctccaggggcaggctgaacagc
caccccatcttttctctcaactgggagtgtgtggtcagtttcctgtggaacacagaggct
gcctgtcccattcagacaacgacggatacagaccaggcttgctctataagggatcccaac
agtggatttgtgtttaatcttaatccgctaaacagttcgcaaggatataacgtctctggc
attgggaagatttttatgtttaatgtctgcggcacaatgcctgtctgtgggaccatcctg
ggaaaacctgcttctggctgtgaggcagaaacccaaactgaagagctcaagaattggaag
ccagcaaggccagtcggaattgagaaaagcctccagctgtccacagagggcttcatcact
ctgacctacaaagggcctctctctgccaaaggtaccgctgatgcttttatcgtccgcttt
gtttgcaatgatgatgtttactcagggcccctcaaattcctgcatcaagatatcgactct
gggcaagggatccgaaacacttactttgagtttgaaaccgcgttggcctgtgttccttct
ccagtggactgccaagtcaccgacctggctggaaatgagtacgacctgactggcctaagc
acagtcaggaaaccttggacggctgttgacacctctgtcgatgggagaaagaggactttc
tatttgagcgtttgcaatcctctcccttacattcctggatgccagggcagcgcagtgggg
tcttgcttagtgtcagaaggcaatagctggaatctgggtgtggtgcagatgagtccccaa
gccgcggcgaatggatctttgagcatcatgtatgtcaacggtgacaagtgtgggaaccag
cgcttctccaccaggatcacgtttgagtgtgctcagatatcgggctcaccagcatttcag
cttcaggatggttgtgagtacgtgtttatctggagaactgtggaagcctgtcccgttgtc
agagtggaaggggacaactgtgaggtgaaagacccaaggcatggcaacttgtatgacctg
aagcccctgggcctcaacgacaccatcgtgagcgctggcgaatacacttattacttccgg
gtctgtgggaagctttcctcagacgtctgccccacaagtgacaagtccaaggtggtctcc
tcatgtcaggaaaagcgggaaccgcagggatttcacaaagtggcaggtctcctgactcag
aagctaacttatgaaaatggcttgttaaaaatgaacttcacggggggggacacttgccat
aaggtttatcagcgctccacagccatcttcttctactgtgaccgcggcacccagcggcca
gtatttctaaaggagacttcagattgttcctacttgtttgagtggcgaacgcagtatgcc
tgcccacctttcgatctgactgaatgttcattcaaagatggggctggcaactccttcgac
ctctcgtccctgtcaaggtacagtgacaactgggaagccatcactgggacgggggacccg
gagcactacctcatcaatgtctgcaagtctctggccccgcaggctggcactgagccgtgc
cctccagaagcagccgcgtgtctgctgggtggctccaagcccgtgaacctcggcagggta
agggacggacctcagtggagagatggcataattgtcctgaaatacgttgatggcgactta
tgtccagatgggattcggaaaaagtcaaccaccatccgattcacctgcagcgagagccaa
gtgaactccaggcccatgttcatcagcgccgtggaggactgtgagtacacctttgcctgg
cccacagccacagcctgtcccatgaagagcaacgagcatgatgactgccaggtcaccaac
ccaagcacaggacacctgtttgatctgagctccttaagtggcagggcgggattcacagct
gcttacagcgagaaggggttggtttacatgagcatctgtggggagaatgaaaactgccct
cctggcgtgggggcctgctttggacagaccaggattagcgtgggcaaggccaacaagagg
ctgagatacgtggaccaggtcctgcagctggtgtacaaggatgggtccccttgtccctcc
aaatccggcctgagctataagagtgtgatcagtttcgtgtgcaggcctgaggccgggcca
accaataggcccatgctcatctccctggacaagcagacatgcactctcttcttctcctgg
cacacgccgctggcctgcgagcaagcgaccgaatgttccgtgaggaatggaagctctatt
gttgacttgtctccccttattcatcgcactggtggttatgaggcttatgatgagagtgag
gatgatgcctccgataccaaccctgatttctacatcaatatttgtcagccactaaatccc
atgcacggagtgccctgtcctgccggagccgctgtgtgcaaagttcctattgatggtccc
cccatagatatcggccgggtagcaggaccaccaatactcaatccaatagcaaatgagatt
tacttgaattttgaaagcagtactccttgcttagcggacaagcatttcaactacacctcg
ctcatcgcgtttcactgtaagagaggtgtgagcatgggaacgcctaagctgttaaggacc
agcgagtgcgactttgtgttcgaatgggagactcctgtcgtctgtcctgatgaagtgagg
atggatggctgtaccctgacagatgagcagctcctctacagcttcaacttgtccagcctt
tccacgagcacctttaaggtgactcgcgactcgcgcacctacagcgttggggtgtgcacc
tttgcagtcgggccagaacaaggaggctgtaaggacggaggagtctgtctgctctcaggc
accaagggggcatcctttggacggctgcaatcaatgaaactggattacaggcaccaggat
gaagcggtcgttttaagttacgtgaatggtgatcgttgccctccagaaaccgatgacggc
gtcccctgtgtcttccccttcatattcaatgggaagagctacgaggagtgcatcatagag
agcagggcgaagctgtggtgtagcacaactgcggactacgacagagaccacgagtggggc
ttctgcagacactcaaacagctaccggacatccagcatcatatttaagtgtgatgaagat
gaggacattgggaggccacaagtcttcagtgaagtgcgtgggtgtgatgtgacatttgag
tggaaaacaaaagttgtctgccctccaaagaagttggagtgcaaattcgtccagaaacac
aaaacctacgacctgcggctgctctcctctctcaccgggtcctggtccctggtccacaac
ggagtctcgtactatataaatctgtgccagaaaatatataaagggcccctgggctgctct
gaaagggccagcatttgcagaaggaccacaactggtgacgtccaggtcctgggactcgtt
cacacgcagaagctgggtgtcataggtgacaaagttgttgtcacgtactccaaaggttat
ccgtgtggtggaaataagaccgcatcctccgtgatagaattgacctgtacaaagacggtg
ggcagacctgcattcaagaggtttgatatcgacagctgcacttactacttcagctgggac
tcccgggctgcctgcgccgtgaagcctcaggaggtgcagatggtgaatgggaccatcacc
aaccctataaatggcaagagcttcagcctcggagatatttattttaagctgttcagagcc
tctggggacatgaggaccaatggggacaactacctgtatgagatccaactttcctccatc
acaagctccagaaacccggcgtgctctggagccaacatatgccaggtgaagcccaacgat
cagcacttcagtcggaaagttggaacctctgacaagaccaagtactaccttcaagacggc
gatctcgatgtcgtgtttgcctcttcctctaagtgcggaaaggataagaccaagtctgtt
tcttccaccatcttcttccactgtgaccctctggtggaggacgggatccccgagttcagt
cacgagactgccgactgccagtacctcttctcttggtacacctcagccgtgtgtcctctg
ggggtgggctttgacagcgagaatcccggggacgacgggcagatgcacaaggggctgtca
gaacggagccaggcagtcggcgcggtgctcagcctgctgctggtggcgctcacctgctgc
ctgctggccctgttgctctacaagaaggagaggagggaaacagtgataagtaagctgacc
acttgctgtaggagaagttccaacgtgtcctacaaatactcaaaggtgaataaggaagaa
gagacagatgagaatgaaacagagtggctgatggaagagatccagctgcctcctccacgg
cagggaaaggaagggcaggagaacggccatattaccaccaagtcagtgaaagccctcagc
tccctgcatggggatgaccaggacagtgaggatgaggttctgaccatcccagaggtgaaa
gttcactcgggcaggggagctggggcagagagctcccacccagtgagaaacgcacagagc
aatgcccttcaggagcgtgaggacgatagggtggggctggtcaggggtgagaaggcgagg
aaagggaagtccagctctgcacagcagaagacagtgagctccaccaagctggtgtccttc
catgacgacagcgacgaggacctcttacacatctga

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
3D Structure (10)   
   PDB (10)   
Protein domain (3)   
   Pfam (3)   
All databases (46)   

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