KEGG T01001: 3572

Homo sapiens (human): 3572

Entry

3572 CDS T01001

Gene name

IL6ST, CD130, CDW130, GP130, IL-6RB

Definition

interleukin 6 signal transducer (gp130, oncostatin M receptor)

Orthology

K05060

interleukin 6 signal transducer

Organism

hsa Homo sapiens (human)

Pathway

hsa04060	Cytokine-cytokine receptor interaction
hsa04630	Jak-STAT signaling pathway
hsa05203	Viral carcinogenesis

Class

Environmental Information Processing; Signal transduction; Jak-STAT signaling pathway [PATH:hsa04630]
Environmental Information Processing; Signaling molecules and interaction; Cytokine-cytokine receptor interaction [PATH:hsa04060]
Human Diseases; Cancers; Viral carcinogenesis [PATH:hsa05203]

SSDB

Motif

Pfam:

Lep_receptor_Ig fn3 IL6Ra-bind EpoR_lig-bind Interfer-bind IBN_N

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3L5I 1BQU 1I1R 1PVH 3L5J 3L5H 1P9M 1BJ8

Position

5q11.2

AA seq 857 aa
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD
FQGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ
LPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK
DGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKS
HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINT
EGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSE
STQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVN
EEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGM
PKSYLPQTVRQGGYMPQ

NT seq 2574 nt +upstreamnt +downstreamnt
atgttgacgttgcagacttggctagtgcaagccttgtttattttcctcaccactgaatct
acaggtgaacttctagatccatgtggttatatcagtcctgaatctccagttgtacaactt
cattctaatttcactgcagtttgtgtgctaaaggaaaaatgtatggattattttcatgta
aatgctaattacattgtctggaaaacaaaccattttactattcctaaggagcaatatact
atcataaacagaacagcatccagtgtcacctttacagatatagcttcattaaatattcag
ctcacttgcaacattcttacattcggacagcttgaacagaatgtttatggaatcacaata
atttcaggcttgcctccagaaaaacctaaaaatttgagttgcattgtgaacgaggggaag
aaaatgaggtgtgagtgggatggtggaagggaaacacacttggagacaaacttcacttta
aaatctgaatgggcaacacacaagtttgctgattgcaaagcaaaacgtgacacccccacc
tcatgcactgttgattattctactgtgtattttgtcaacattgaagtctgggtagaagca
gagaatgcccttgggaaggttacatcagatcatatcaattttgatcctgtatataaagtg
aagcccaatccgccacataatttatcagtgatcaactcagaggaactgtctagtatctta
aaattgacatggaccaacccaagtattaagagtgttataatactaaaatataacattcaa
tataggaccaaagatgcctcaacttggagccagattcctcctgaagacacagcatccacc
cgatcttcattcactgtccaagaccttaaaccttttacagaatatgtgtttaggattcgc
tgtatgaaggaagatggtaagggatactggagtgactggagtgaagaagcaagtgggatc
acctatgaagatagaccatctaaagcaccaagtttctggtataaaatagatccatcccat
actcaaggctacagaactgtacaactcgtgtggaagacattgcctccttttgaagccaat
ggaaaaatcttggattatgaagtgactctcacaagatggaaatcacatttacaaaattac
acagttaatgccacaaaactgacagtaaatctcacaaatgatcgctatctagcaacccta
acagtaagaaatcttgttggcaaatcagatgcagctgttttaactatccctgcctgtgac
tttcaagggaacttagcagagagcaaatgctatttgataacagttactccagtatatgct
gatggaccaggaagccctgaatccataaaggcataccttaaacaagctccaccttccaaa
ggacctactgttcggacaaaaaaagtagggaaaaacgaagctgtcttagagtgggaccaa
cttcctgttgatgttcagaatggatttatcagaaattatactatattttatagaaccatc
attggaaatgaaactgctgtgaatgtggattcttcccacacagaatatacattgtcctct
ttgactagtgacacattgtacatggtacgaatggcagcatacacagatgaaggtgggaag
gatggtccagaattcacttttactaccccaaagtttgctcaaggagaaattgaagccata
gtcgtgcctgtttgcttagcattcctattgacaactcttctgggagtgctgttctgcttt
aataagcgagacctaattaaaaaacacatctggcctaatgttccagatccttcaaagagt
catattgcccagtggtcacctcacactcctccaaggcacaattttaattcaaaagatcaa
atgtattcagatggcaatttcactgatgtaagtgttgtggaaatagaagcaaatgacaaa
aagccttttccagaagatctgaaatcattggacctgttcaaaaaggaaaaaattaatact
gaaggacacagcagtggtattggggggtcttcatgcatgtcatcttctaggccaagcatt
tctagcagtgatgaaaatgaatcttcacaaaacacttcgagcactgtccagtattctacc
gtggtacacagtggctacagacaccaagttccgtcagtccaagtcttctcaagatccgag
tctacccagcccttgttagattcagaggagcggccagaagatctacaattagtagatcat
gtagatggcggtgatggtattttgcccaggcaacagtacttcaaacagaactgcagtcag
catgaatccagtccagatatttcacattttgaaaggtcaaagcaagtttcatcagtcaat
gaggaagattttgttagacttaaacagcagatttcagatcatatttcacaatcctgtgga
tctgggcaaatgaaaatgtttcaggaagtttctgcagcagatgcttttggtccaggtact
gagggacaagtagaaagatttgaaacagttggcatggaggctgcgactgatgaaggcatg
cctaaaagttacttaccacagactgtacggcaaggcggctacatgcctcagtga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (14)   
   UniGene (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (2)   
   RefSeq(pep) (3)   
DNA sequence (45)   
   RefSeq(nuc) (3)   
   GenBank (21)   
   EMBL (21)   
3D Structure (8)   
   PDB (8)   
Protein domain (6)   
   Pfam (6)   
All databases (93)   

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