KEGG T01001: 3651

Homo sapiens (human): 3651

Entry

3651 CDS T01001

Gene name

PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1

Definition

pancreatic and duodenal homeobox 1

Orthology

K07594

insulin promoter factor 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04911	Insulin secretion
hsa04930	Type II diabetes mellitus
hsa04950	Maturity onset diabetes of the young

Disease

H00410	Maturity onset diabetes of the young (MODY)
H00512	Permanent neonatal diabetes mellitus (PNDM)
H00861	Pancreatic agenesis

Class

Organismal Systems; Endocrine system; Insulin secretion [PATH:hsa04911]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:hsa04930]
Human Diseases; Endocrine and metabolic diseases; Maturity onset diabetes of the young [PATH:hsa04950]

SSDB

Motif

Pfam:

Homeobox

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

13q12.1

AA seq 283 aa
MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQG
SPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFP
WMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELA
VMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPP
PPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR

NT seq 852 nt +upstreamnt +downstreamnt
atgaacggcgaggagcagtactacgcggccacgcagctttacaaggacccatgcgcgttc
cagcgaggcccggcgccggagttcagcgccagcccccctgcgtgcctgtacatgggccgc
cagcccccgccgccgccgccgcacccgttccctggcgccctgggcgcgctggagcagggc
agccccccggacatctccccgtacgaggtgccccccctcgccgacgaccccgcggtggcg
caccttcaccaccacctcccggctcagctcgcgctcccccacccgcccgccgggcccttc
ccggagggagccgagccgggcgtcctggaggagcccaaccgcgtccagctgcctttccca
tggatgaagtctaccaaagctcacgcgtggaaaggccagtgggcaggcggcgcctacgct
gcggagccggaggagaacaagcggacgcgcacggcctacacgcgcgcacagctgctagag
ctggagaaggagttcctattcaacaagtacatctcacggccgcgccgggtggagctggct
gtcatgttgaacttgaccgagagacacatcaagatctggttccaaaaccgccgcatgaag
tggaaaaaggaggaggacaagaagcgcggcggcgggacagctgtcgggggtggcggggtc
gcggagcctgagcaggactgcgccgtgacctccggcgaggagcttctggcgctgccgccg
ccgccgccccccggaggtgctgtgccgcccgctgcccccgttgccgcccgagagggccgc
ctgccgcctggccttagcgcgtcgccacagccctccagcgtcgcgcctcggcggccgcag
gaaccacgatga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (7)   
   KEGG DISEASE (3)   
   OMIM (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
Protein domain (1)   
   Pfam (1)   
All databases (44)   

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