KEGG T01001: 3768

Homo sapiens (human): 3768

Entry

3768 CDS T01001

Gene name

KCNJ12, IRK-2, IRK2, KCNJN1, Kir2.2, Kir2.2v, hIRK, hIRK1, hkir2.2x, kcnj12x

Definition

potassium inwardly-rectifying channel, subfamily J, member 12

Orthology

K05005

potassium inwardly-rectifying channel subfamily J member 12

Organism

hsa Homo sapiens (human)

Pathway

hsa04725

Cholinergic synapse

Drug target

Amiodarone:

D00636 D02910

Bepridil:

D00631 D07520

Other:

D01856 D09757

Class

Organismal Systems; Nervous system; Cholinergic synapse [PATH:hsa04725]

SSDB

Motif

Pfam:

IRK IRK_N Ion_trans_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

17p11.2

AA seq 433 aa
MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
VLEQRPYRRESEI

NT seq 1302 nt +upstreamnt +downstreamnt
atgaccgcggccagccgggccaacccctacagcatcgtgtcatcggaggaggacgggctg
cacctggtcaccatgtcgggcgccaacggcttcggcaacggcaaggtgcacacgcggcgc
aggtgccgcaaccgcttcgtcaagaagaatggccagtgcaacattgagttcgccaacatg
gacgagaagtcacagcgctacctggctgacatgttcaccacctgtgtggacatccgctgg
cggtacatgctgctcatcttctcgctggccttccttgcctcctggctgctgttcggcatc
atcttctgggtcatcgcggtggcacacggtgacctggagccggctgagggccggggccgc
acaccctgtgtgatgcaggtgcacggcttcatggcggccttcctcttctccatcgagacg
cagaccaccatcggctacgggctgcgctgtgtgacggaggagtgcccggtggccgtcttc
atggtggtggcccagtccatcgtgggctgcatcatcgactccttcatgattggtgccatc
atggccaagatggcaaggcccaagaagcgggcacagacgctgctgttcagccacaacgcc
gtggtggccctgcgtgacggcaagctctgcctcatgtggcgtgtgggtaacctgcgcaag
agccacattgtggaggcccatgtgcgcgcgcagctcatcaagccgcgggtcaccgaggag
ggcgagtacatcccgctggaccagatcgacatcgatgtgggcttcgacaagggcctggac
cgcatctttctggtgtcgcccatcaccatcttgcatgagattgacgaggccagcccgctc
ttcggcatcagccggcaggacctggagacggacgactttgagatcgtggtcatcctggaa
ggcatggtggaggccacagccatgaccacccaggcccgcagctcctacctggccaatgag
atcctgtggggtcaccgctttgagcccgtgctcttcgaggagaagaaccagtacaagatt
gactactcgcacttccacaagacctatgaggtgccctctacgccccgctgcagtgcgaag
gatctggtagagaacaagttcctgctgcccagcgccaactccttctgctacgagaacgag
ctggccttcctgagccgtgacgaggaggatgaggcggacggagaccaggacggccgaagc
cgggacggcctcagcccccaggccaggcatgactttgacagactccaggctggcggcggg
gtcctggagcagcggccctacagacgggagtcagagatctga

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (3)   
   Pfam (3)   
All databases (49)   

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